A presença de patógenos respiratórios no biofilme bucal de pacientes com pneumonia nosocomial

Abstract

0,05). CONCLUSÕES: Os resultados deste estudo sugeriram que a presença de patógenos respiratórios no biofilme bucal de pacientes internados em UTI pode servir de reservatório para micro-organismos associados com pneumonia nosocomial.]]>

Impactos e fatores determinantes no bundle de pneumonia associada à ventilação mecânica

“…An inadequate oral hygiene along with the use of drugs will alter the salivation ability, as well as its pH, promoting an increase in the amount of bacteria in the oral biofilm, which -along with procedures such as aspiration, feeding, or any other form of manipulation of the patient -can facilitate contamination of the lower respiratory tract and the development of pneumonia (17) .…”

“…In another study, it was observed that when Pseudomonas aeruginosa and Klebsiella pneumoniae were identified as etiological agents, they were located beyond the tracheal aspirate, in the humidifier tube and/or dental and tongue biofilm, highlighting the importance of oral hygiene and replacement of devices in the prevention of ventilator-associated pneumonia (17) .…”

Pneumonia nosocomial: importância do microambiente oral

“…(8) Nosocomial pneumonia is defined as an infection of the lower respiratory tract that is diagnosed at least 48 h after the patient has been admitted to hospital, which is not present or incubating at the time of hospital admission. (2,6,9,10) There is also the healthcareassociated pneumonia category, which refers to pneumonia associated with patients residing in nursing homes or receiving home care, with patients who received i.v. antimicrobial agents or chemotherapy within 30 days before the onset of the infection, with patients receiving renal replacement therapy or with patients who needed emergency treatment and were hospitalized for 2 or more days within the 90 days preceding the onset of the infection.…”

“…Because of etiological, therapeutic and prognostic implications, HAP has been classified, according to the time elapsed since hospital admission until its onset, as early (which develops within four days of (1,6,(13)(14)(15)19,22,32,34,35) , are not commonly observed in the oral and oropharyngeal microbiota, these organisms can colonize the oral cavity in certain situations, such as in cases of precarious sanitation, of institutionalized elderly and of ICU patients. (6,10,20,22) In such cases, the percentage of these bacteria in the mouth can be as high as 70% in the dental biofilm, 63% on the tongue and 73% on the ventilator tube. When these areas are analyzed as a single system, the population of these organisms might be up to 43% of the total percentage of oral bacteria in patients on MV.…”

“…(5)(6)(7)(8) The use of oral antiseptic and antimicrobial agents to prevent nosocomial pneumonia has been widely studied and, based on what has been reported, the present study aimed to review the literature focusing on how oral microorganisms can influence the development of nosocomial pneumonia and on how the frequency of nosocomial pneumonia can be reduced by changing the oral environment. …”