A New Depside Isolated from the Bark of Rauwolfia mattfeldiana

Vieira, Ivo José Curcino; Cecchi, Christian M.P.; Mathias, Lêda; Braz-Filho, Raimundo; Rodrigues‐Filho, Edson

doi:10.1590/s0103-50531998000100016

Cited by 4 publications

(2 citation statements)

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“…Lichexanthone can be obtained synthetically [8] or isolated from natural products [9] and lichens [10]. Kathirgamanathar et al [11] showed that lichexanthone has larvicidal activity against secondinstar larvae of the mosquito Aedes aegypti and that it enhances human sperm motility.…”

Section: Introductionmentioning

confidence: 99%

Electroreduction of lichexanthone

Carvalho

Alcantara

Oliveira

et al. 2009

Electrochimica Acta

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Section: Introductionmentioning

confidence: 99%

Electroreduction of lichexanthone

Carvalho

Alcantara

Oliveira

et al. 2009

Electrochimica Acta

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“…1. Based on all spectroscopic data, literature values (31) and melting point of the compound, it was confirmed that the compound AS-1 is 6-Hydroxy-1, 3-dimethoxy-7methyl-xanthen-9-one. Finally, the structure of the compound was confirmed by the fragment ions present in the mass spectrum.…”

Section: Discussionmentioning

confidence: 68%

Four bioactive compounds isolated from the stem of Anethum sowa L. and their bioactivities

2023

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Anethum sowa Roxb., (a well-known herb in folk medicine, has a greater medicinal significance due to its diversified activities such as antioxidant, antimicrobial and antispasmodic activity. Very few bioactive compounds have been reported from this species. Our study focused on the isolation, structure elucidation and bioactivity assay of the compounds. In the present work, 6-hydroxy-1, 3-dimethoxy-7-methyl-xanthen-9-one (AS-1) from dichloromethane extract and scopoletin (AS-2), 1, 3, 4-trimethoxy-xanthen-9-one (AS-3), graveolone (AS-4) from ethyl acetate extract of stem of A. sowa were isolated from the stem as well as the plant for the first time. All the characterizations and chemical structures of the compounds were determined by extensive modern spectroscopic techniques such as ultraviolet (UV), infrared (IR), mass, Nuclear Magnetic Resonance (NMR) spectrophotometer. Moreover, the cytotoxic, antimicrobial and antioxidant activity of AS-2, AS-3 and AS-4 were assessed. AS-2 exhibited significant activity against Salmonella typhi while mild antifungal activity against Aspergillus niger. Furthermore AS-3 revealed significant antifungal activity against Sacharomyces cerevacae as well as antibacterial activity against Salmonella typhi. Besides AS-4 exhibited moderate antibacterial activity against Bacillus megaterium. In addition AS-2, AS-3 and AS-4 presented mild cytotoxic with respect to positive control (Vincristine sulphate) while AS-3 exhibited moderate antioxidant activity as compared to positive control (Ascorbic acid).

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