Osteointegração de osso bovino desvitalizado, hidroxiapatita de coral, poliuretana de mamona e enxerto autógeno em coelhos

Abstract

RESUMOOBJETIVO: Estudar comparativamente implantes de osso bovino desvitalizado, hidroxiapatita porosa de coral, poliuretana de mamona e enxerto ósseo autógeno no reparo de defeito ósseo de 6x10mm em fêmur de coelhos. MÉTODOS: Noventa e seis coelhos Nova Zelândia distribuídos em 4 grupos conforme o material de preenchimento do defeito ósseo. Após seguimento de 4 e 12 semanas, as peças foram submetidas a análise macroscópica, microscópica, radiográfica, tomográfica e histométrica. Aos resultados aplicou-se testes estatísticos de Kruskal-Wallis, Mann-Whitney, Fisher, "t" de Student e quiquadrado. RESULTADOS : O enxerto ósseo autógeno mostrou maior potencial osteogênico; o osso bovino desvitalizado produz maior reação inflamatória, maior número de cavidades císticas e lentidão de integração; a hidroxiapatita porosa de coral mantém a radiodensidade inicial; os implantes de osso bovino desvitalizado e poliuretana de mamona mostraram radiodensidades aumentadas conforme foram invadidos pelo tecido ósseo neoformado. CONCLUSÃO: O implante de osso bovino desvitalizado induz reparação tecidual guiada mais lenta quando comparado ao enxerto ósseo autógeno e aos implantes de hidroxiapatita porosa de coral e poliuretana de mamona.Descritores: Osso bovino. Hidroxiapatita. Polímero. Transplante autógeno. Coelhos. ABSTRACT PURPOSE:To study comparatively devitalized bovine bone, porous coralline hydroxyapatite, castor beans polyurethane implants and autograft in the repair of 6x10mm bony defect in femur of rabbits.

Effect of 650 nm low-power laser on bone morphogenetic protein in bone defects induced in rat femors<A NAME="volta1"></A>

“…Nonetheless, Groups 2 and 3 also presented favorable results, with the presence of bone trabeculae and osteoblasts aligned within these, and the presence of a poorly defined medullary canal of small dimensions can be highlighted in Group 2. These results confirm other studies 7,8,[15][16][17] in which low-power laser in association with filling the bone defects with BMPs accelerated bone neoformation. Our study also corroborates studies 4,15 that presented favorable results from grafts using BMPs, in which bone incorporation occurred more rapidly and the repair took place with intense bone neoformation.…”

“…The same could be observed in the histopathological analysis, and these results are affirmed by similar studies. Another study comparing different biomaterials concluded that, although devitalized bovine bone presented greater inflammatory reaction with the presence of giant cells of foreign body type, formation of cystic cavities containing implant residues and slower pore invasion by bone tissue, in comparison with other implants, this bone material showed osteoconductive properties in bone defect repairs 17 . In the present study, the results indicate that there was an inflammatory reaction of lesser intensity and duration in the groups that were subjected to irradiation using low-power laser, and this is corroborated by the results achieved by other studies using laser.…”

Ricinus communis biocompatibility histological study in the nose of Cebus apella monkeys

“…Studies by Vilarinho et al 6 , Suguimoto 13 , Souza et al 16 , Cavalieri 17 used the castor bean polymer in the most bean polymer was biocompatible, there was biomaterial persistence 270 days after surgery and the implant did not induce bone neoformation.…”

Absence of the right forelimb in Corythomantis greeningi Boulenger, 1896: case report

“…The application of the X-ray is a diagnostic method for the bone tissue (FIGUEIREDO et al, 2004;OLIVEIRA et al, 2006), providing important information regarding fractures, tumors, degenerative conditions and osteomyelitis, also providing valuable information about the ossification process (CRUZ et al, 2007). In our study the radiographic characteristics were indicative of the presence of humerus, with an irregular but well-calcified morphology.…”