Minisuíno (minipig) na pesquisa biomédica experimental: o Minipig br1

Mariano, Mário

doi:10.1590/s0102-86502003000500003

Cited by 33 publications

(33 citation statements)

References 1 publication

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“…The "Minipig br" has been bred in Brazil. 16 Whatever the experimental model chosen, a critical analysis must be made of the limitations imposed by the physical and anatomical differences from humans and of the diseases that can potentially be contextualized.…”

Section: Choice Of Experimental Model and Genetic Standardizationmentioning

confidence: 99%

Aspectos fundamentais da experimentação animal - aplicações em cirurgia experimental

Damy¹,

Camargo²,

Chammas³

et al. 2010

Rev. Assoc. Med. Bras.

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With the objective of contributing to research in experimental surgery, this article presents an analysis of the principal parameters laid down by Brazilian and international ethics and animal welfare committees and which must be adhered to for publication in international peer-reviewed journals. Standardization of the genetics, sanitary status and environment of the species Mus musculus (mice), Rattus norvegicus (rats), Oryctolagus cuniculus (rabbits) and Sus scropha domesticus (pigs), appropriate transportation, acclimatization, enrichment of the environment, training of animal science technicians, information management, biosafety, diet, anesthesia, postoperative care, analgesia and euthanasia, in combination with well-planned research protocols are presented as the basic elements for achieving results with a high degree of acuity, reproducibility and precision.

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Section: Choice Of Experimental Model and Genetic Standardizationmentioning

confidence: 99%

Aspectos fundamentais da experimentação animal - aplicações em cirurgia experimental

Damy¹,

Camargo²,

Chammas³

et al. 2010

Rev. Assoc. Med. Bras.

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“…The use of swine as experimental model is referred in Medicine since 1540 (10) . Swine are used in research based on application or improvement of ophthalmic surgical techniques as well as experi mental models of ocular diseases.…”

Section: Discussionmentioning

confidence: 99%

Composition of intraocular foreign bodies: experimental study of ultrasonographic presentation

Costa

Garcia

Barroso

et al. 2013

Arq. Bras. Oftalmol.

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Purpose: To investigate the reliability of ultrasound in determining the size and identify the sonographic features and artifacts generated by intraocular foreign bodies of different materials. Methods: Experimental study using 36 enucleated porcine eyes. Fragments of nine different compositions (wood, glass, plastic, cardboard, iron, aluminum, lead, powder and concrete) and similar dimensions (4 mm) were implanted via scleral incision into the vitreous cavity of 36 porcine eyes, four eyes were used for each material. Ultrasound examination was performed in all eyes using the contact technique, conductive gel and 10MHz transducer (EZScan, Sonomed). Results: Considering the material fragments of gunpowder, lead, concrete, alu minum, wood and glass, the size determined by ultrasound was considered statistically similar to the actual size. The material iron presented ultrasoundde termined dimension statistically smaller than its actual size. Cardboard and plastic materials showed ultrasounddetermined measurements far greater than the actual. All fragments of intraocular foreign bodies demonstrated hyperreflective interfaces, irrespective of their composition. Whereas the artifacts generated by different materials, it was found that the materials iron, aluminum and lead showed reverberation of great extent. The material wood showed no reverberation. The length of the reverberation artifact for the materials iron, glass, aluminum and cardboard was lower when compared to other materials. All materials presented posterior shadowing artifact, with the exception of aluminum. Conclusion: Ultrasonography was considered a reliable technique to determine the size of intraocular foreign bodies in pigs, with little influence caused by its composition. Ultrasound artifacts generated were considered materialdependent and can assist the examiner to identify the nature of a foreign body of unknown etiology. Ultrasonography aided the surgeon to identify, locate and measure the intraocular foreign body, directing appropriate surgical planning.

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“…Este material foi selecionado de acordo com a realização de estudos anteriores na Odontologia, que utilizaram o osso suíno como substituto do osso da mandíbula e maxila humana, devido a sua similaridade nas trabéculas ósseas e osso cortical (Rocha, 2010;Buser et al, 1998;Mariano et al, 2003;Nkenke et al, 2003).…”

Section: Corpos-de-prova De Costela Suínaunclassified

“…O osso de costela suíno foi utilizado com um grupo controle, substituto do osso humano, por apresentar anisotropia e um arranjo trabecular similar ao osso de maxila e mandíbula humana (Mariano, 2003;Nkenke et al, 2003).…”

Section: Substrato Para Inserção Dos Implantesunclassified

Influência do desing, tratamento de superfície e densidade do substrato na estabilidade primária de implantes odontológicos. Análise por meio de torque de inserção, resistência ao arrancamento e freqüência de ressonância

Oliscovicz¹

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Minisuíno (minipig) na pesquisa biomédica experimental: o Minipig br1

Cited by 33 publications

References 1 publication

Aspectos fundamentais da experimentação animal - aplicações em cirurgia experimental

Aspectos fundamentais da experimentação animal - aplicações em cirurgia experimental

Composition of intraocular foreign bodies: experimental study of ultrasonographic presentation

Influência do desing, tratamento de superfície e densidade do substrato na estabilidade primária de implantes odontológicos. Análise por meio de torque de inserção, resistência ao arrancamento e freqüência de ressonância

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