Efeitos Do Extrato Aquoso Da Hyptis Pectinata Sobre a Regeneração Hepática Após Hepatectomia Parcial De 70%: Resultados Preliminares

Melo, Gustavo Barreto; Silva, R. L.; Antoniolli, Ângelo Roberto; Melo, Valdinaldo Aragão de; Lima, Sônia Oliveira; Silva, P. M. da; Silva, O. de C.

doi:10.1590/s0102-86502001000500005

Cited by 4 publications

(2 citation statements)

References 3 publications

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“…The results obtained in this research indicated that women continue to be the holders of this folk knowledge which corroborate with results from previous research, where the highest number interviewees are females. Another possible explanation for this is that men were absent from home or the healthcare units for work reasons (Melo et al 2001;Arnous et al 2005;Marinho et al, 2011). The interviewed women were mostly housewives, which explains their in-person availability to participate in the research.…”

Section: Discussionmentioning

confidence: 99%

Ethnodirigid study of Medicinal plants used by the population assisted by the “Programa de Saúde da Família” (Family Health Program) in Marechal Deodoro - AL, Brazil

et al. 2020

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Abstract This study aimed to assess diagnosis of Unique Health System (SUS) users profile with regard to herbal medicine. This is a cross-sectional study with observational data collection conducted in the city of Marechal Deodoro, through a semi-structured questionnaire with questions related to socioeconomic data, use, and knowledge of medicinal plants and herbal medicines and satisfaction with the use of medicinal herbs (MH) and interactions of phytotherapeutic drugs (PD). Among the topics, 86.89% of users used herbal medicines often, especially lemon balm (Melissa officinalis L.). It was also observed that the plants are generally used as a sedative (21.74%) and as tea (87.84%). 82.32% of respondents claim to have acquired the knowledge of herbal medicine through a family member and 85.36% make use of medicinal plants without having received any information on the use of MH and PD. 61% of the plants described that coincided with the form of use and therapeutic properties found in the literature. With regard to satisfaction by treatment with MH and PD, it was found that 56.67% are satisfied. Therefore, it is necessary to pay attention to this aspect of usage, in order to avoid possible drug interactions or adverse reactions resulting from the incorrect use.

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Section: Discussionmentioning

confidence: 99%

Ethnodirigid study of Medicinal plants used by the population assisted by the “Programa de Saúde da Família” (Family Health Program) in Marechal Deodoro - AL, Brazil

et al. 2020

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“…Os efeitos antiedematogênico e antinociceptivo foram comprovados a partir de seu extrato aquoso 8 . Também foi comprovado seu efeito hepatoprotetor após hepatectomia parcial 9 . O óleo essencial da Hyptis pectinata contém 33 compostos, com predominância de monoterpenos (95,8%).…”

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Efeito do extrato aquoso da Hyptis pectinata sobre a proliferação de hepatócitos após hepatectomia parcial

Silva¹,

Melo²,

Antoniolli³

et al. 2002

Acta Cir. Bras.

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OBJETIVO: O uso de plantas medicinais tem aumentado mundialmente. Então, é necessário saber seus possíveis efeitos a fim de estabelecer seu uso correto em seres humanos. Dessa forma, neste trabalho se propôs a estudar os efeitos do extrato aquoso das folhas da Hyptis pectinata, popularmente conhecida como "sambacaitá" ou "canudinho", sobre a regeneração hepática após hepatectomia parcial em ratos. MÉTODOS: Dez ratos foram divididos em 2 grupos: grupos HP, que foi submetido à hepatectomia de 67% após 4 dias de administração de água destilada; e o grupo HP100, que foi submetido à hepatectomia parcial e administração oral de 100 mg/kg do extrato aquoso da Hyptis pectinata pelo mesmo período de tempo. Todos os animais foram sacrificados 24 horas após o procedimento cirúrgico. A regeneração foi analisada através do método de imuno-histoquímica PCNA, usando o anticorpo monoclonal PC-10. RESULTADOS: O índice de regeneração hepática estava significativamente elevado no grupo HP100 (p<0,05). CONCLUSÕES: O presente estudo mostra que o extrato aquoso das folhas da Hyptis pectinata pode estimular a regeneração hepática na concentração de 100 mg/kg.

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Enhancement of Liver Regeneration by the Association of Hyptis pectinata with Laser Therapy

et al. 2005

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Since new molecules that normally would accelerate regeneration can also be potentialized by light, the use of new substances combined with laser therapy seems to be a natural type of experiment. Therefore, the purpose of this study was to assess the effects of Hyptis pectinata leaves on liver regeneration after partial hepatectomy (PH) associated with laser therapy. Twenty-four rats were divided into four groups--PH(control), PHL (laser therapy), PH200 (200 mg/kg of Hyptispectinata), and PHL200 (200 mg/kg of the plant and laser)--which were submitted to 67% hepatectomy. Laser treatment consisted of focusing the light on the remaining liver after hepatectomy. The data analyzed were serum levels of aminotransferases, liver regeneration, and mitochondrial function. Group PH200 showed a statistically significant decrease in AST levels, and PHL200 disclosed an augmentation in ALT levels. The liver regeneration index was significantly increased in group PHL200. Concerning liver mitochondrial respiratory assay, groups PH200 and PHL200 showed lower state 3 levels than groups PH and PHL. Group PHL showed an increase in state 4 levels and a reduction in membrane potential and RCR. The present study shows that the association of the aqueous extract of Hyptis pectinata leaves at 200 mg/kg with intraoperative laser therapy can stimulate liver regeneration and cause a reduction in liver mitochondrial respiratory function without altering its phosphorylative activity.

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Efeitos Do Extrato Aquoso Da Hyptis Pectinata Sobre a Regeneração Hepática Após Hepatectomia Parcial De 70%: Resultados Preliminares

Cited by 4 publications

References 3 publications

Ethnodirigid study of Medicinal plants used by the population assisted by the “Programa de Saúde da Família” (Family Health Program) in Marechal Deodoro - AL, Brazil

Ethnodirigid study of Medicinal plants used by the population assisted by the “Programa de Saúde da Família” (Family Health Program) in Marechal Deodoro - AL, Brazil

Efeito do extrato aquoso da Hyptis pectinata sobre a proliferação de hepatócitos após hepatectomia parcial

Enhancement of Liver Regeneration by the Association of Hyptis pectinata with Laser Therapy

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