Marine natural products: chemical and biological potential of seaweeds and their endophytic fungi

Oliveira, Ana Lígia Leandrini de; Felício, Rafael de; Debonsi, Hosana Maria

doi:10.1590/s0102-695x2012005000083

Cited by 30 publications

(16 citation statements)

References 99 publications

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“…Bromophenols (C 6 H 5 BrO) are present as impurities in synthetic chemicals 54 and are produced by marine algae 26 and bacteria 55 . They have been detected in a variety of marine organisms, including polychaetes, sponges, bryozoans, and fishes 26,56 , and are of interest due to their antioxidant and anticancer properties 57 . Tribromophenol and 2,4,6tribromo anisole (p. 98 and 96), a closely related structural homolog, were also detected in our samples (Table 2).…”

Section: Resultsmentioning

confidence: 99%

Nontargeted Screening of Halogenated Organic Compounds in Bottlenose Dolphins (Tursiops truncatus) from Rio de Janeiro, Brazil

Alonso

Maruya

Dodder

et al. 2017

Environ. Sci. Technol.

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To catalog the diversity and abundance of halogenated organic compounds (HOCs) accumulating in high trophic marine species from the southwestern Atlantic Ocean, tissue from bottlenose dolphins (Tursiops truncatus) stranded or incidentally captured along the coast of Rio de Janeiro, Brazil, were analyzed by a non-targeted approach based on GC×GC/TOF-MS. A total of 158 individual HOCs from 32 different structural classes were detected in the blubber of 4 adult male T. truncatus. Nearly 90 percent of the detected compounds are not routinely monitored in the environment. DDT-related and mirex/dechlorane-related compounds were the most abundant classes of anthropogenic origin. Methoxy-brominated diphenyl ethers and chlorinated methyl- and dimethyl bipyrroles (MBPs and DMBPs) were the most abundant natural products. Reported for the first time in southwestern Atlantic cetaceans and in contrast to North American marine mammals, chlorinated MBPs and DMBPs were more diverse and abundant than their brominated and/or mixed halogenated counterparts. HOC profiles in coastal T. tursiops from Brazil and California revealed a distinct difference, with a higher abundance of mirex/dechloranes and chlorinated bipyrroles in the Brazilian dolphins. Thirty-six percent of the detected HOCs had an unknown structure. These results suggest broad geographical differences in the patterns of bioaccumulative chemicals found in the marine environment, and indicate the need to develop more complete catalogs of HOCs from various marine environments.

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Section: Resultsmentioning

confidence: 99%

Nontargeted Screening of Halogenated Organic Compounds in Bottlenose Dolphins (Tursiops truncatus) from Rio de Janeiro, Brazil

Alonso

Maruya

Dodder

et al. 2017

Environ. Sci. Technol.

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“…Combining the particulars of the marine environment and microbial versatility, marine microorganisms have been considered as a new frontier for finding novel pharmaceutical candidates [40]. According to the "one strain, many compounds" concept, different culture conditions result in the chemical diversity of the compounds [41].…”

Section: Extraction and Characterization Of Bioactive Compounds From mentioning

confidence: 99%

Marine Algicolous Endophytic Fungi - A Promising Drug Resource of the Era

Sarasan

Puthumana

Job

et al. 2017

Journal of Microbiology and Biotechnology

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Endophytic fungi have currently been acknowledged as the most promising source of bioactive compounds for drug discovery, and considerable progress has been made in exploring their diversity, species richness, and bioprospecting. Fungal endophytes from unique environmental settings offer a pool of potentially useful medicinal entities. Owing to the constant stresses imposed on macroalgae by marine environments, it is believed that algae and their associated endophytic symbionts represent a good source of structurally diverse bioactive secondary metabolites. Despite the proven significance of active metabolites of algal endophytes, little have been exploited. This review highlights the latest discoveries in algicolous endophytic research, with particular focus on the bioactive metabolites from algal endophytes. Compounds are classified according to their reported biological activities, like anticancer, antibacterial, antifungal, and antioxidant properties. Present experimental evidence suggests that a majority of the bioactive metabolites were reported from Phaeophyceae followed by Rhodophyceae and Chlorophyceae. An intensive search for newer and more effective bioactive metabolites has generated a treasure trove of publications, and this review partially covers the literature published up to 2016.

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“…grow in the lower subtidal zone, attached to the sand substrate or broken rock or on mangrove roots or mangrove branches that are broken and stuck in the mud. The percentage of the existence of this algae is only around 13% of all types of algae that grow naturally [2]. Caulerpa lentillifera has advantages as a functional food because of its high nutritional composition [3].…”

Section: Introductionmentioning

confidence: 99%

Comparative Analysis of The Two Sites of Lahe (Caulerpa sp.) Growth for Determine The Range of Atmospheric, Physical and Chemical Water Conditions

Medellu

Suriani

Komansilan

2020

Preprint

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Background Ecological conditions determine the growth and productivity of lahe (Caulerpa Sp.). We conduct a comparative study of ecological conditions that affected differences in growth and productivity of lahe in two locations, in the Batunderang village area and the Lapango village area, Sangihe Regency. The ecological factors that we examined include atmospheric, chemical and physical factors. Atmospheric variables include radiation intensity, duration of irradiation, the air temperature above sea level. The physical and chemical parameters of water studied include current velocity, seawater temperature, salinity, current strength, pH, dissolved oxygen, and nitrate concentrations. Results The indicator of lahe growth are: chain length, stem diameter, meristem diameter. The productivity indicator is the wet weight of the lahe harvested by farmers within 90 days. Comparative analysis between locations and measurement positions summarizes the range of ecological conditions for natural growth. The seabed for lahe is 0.8 m − 1.4 m lower than the surface of a coral reef and is not exposed at the lowest tide. The air temperature range at position 20 cm above sea level is 250C − 31.60C, while the temperature of seawater varies between 250C to 28.40C. Daily fluctuations in current velocity at high tides range from 0.09 cm/sec to 2 cm/sec. The salinity range between 27.8 ppt to 28.6 ppt. The pH range of seawater for natural growth is 7.6–8.12, while the dissolved oxygen range is 6 ppm to 6.25 ppm. Nitrate concentrations in lahe growth positions vary between 1.8 ppm − 1.96 ppm. Conclusion This ecological condition guarantees that the productivity of lahe varies between 20–30 kg/m2 for a 90-day harvest period.

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Marine natural products: chemical and biological potential of seaweeds and their endophytic fungi

Cited by 30 publications

References 99 publications

Nontargeted Screening of Halogenated Organic Compounds in Bottlenose Dolphins (Tursiops truncatus) from Rio de Janeiro, Brazil

Nontargeted Screening of Halogenated Organic Compounds in Bottlenose Dolphins (Tursiops truncatus) from Rio de Janeiro, Brazil

Marine Algicolous Endophytic Fungi - A Promising Drug Resource of the Era

Comparative Analysis of The Two Sites of Lahe (Caulerpa sp.) Growth for Determine The Range of Atmospheric, Physical and Chemical Water Conditions

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