Teor de bixina em quatro variedades de Bixa orellana L. cultivadas na Paraíba

Barbosa-Filho, José Maria; Silva-Filho, Raimundo Nonato da; Lira, Bruno Freitas; Macêdo, Rui Oliveira; Silva, Marcelo Sobral da; Chaves, María Célia de Oliveira; Souza, María de Fátima Vanderlei de; Cunha, Emídio Vasconcelos Leitão da; Athayde-Filho, Petrônio Filgueiras de

doi:10.1590/s0102-695x1998000100005

Cited by 10 publications

(7 citation statements)

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“…The Bixin powder was extracted from seeds according to the methodology established by Barbosa et al (1998); polycaprolactone (PCL), with a molecular weight of 43,000–50,000 kDa, was purchased from Polyscience, Inc. (Warrington); dichlorometane (DCM), methanol (MeOH), and ammonium acetate were purchased from Sigma Aldrich. All reagents were of analytical grade.…”

Section: Methodsmentioning

confidence: 99%

Efficient cutaneous wound healing using bixin-loaded PCL nanofibers in diabetic mice

Pinzón-García

Cassini‐Vieira

Ribeiro

et al. 2016

J. Biomed. Mater. Res.

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The present work demonstrated an efficient cutaneous wound healing using Bixin-loaded polycaprolactone (PCL) nanofibers as a controlled delivery system. The influence of Bixin (Bix) content on PCL nanofiber, Bix-PCL1(2.5% w/w bix) and Bix-PCL2 (12.5% w/w bix) formation was investigated using electrical conductivity, attenuated total reflectance infrared spectroscopy, X-ray diffraction, thermal analysis, and scanning electronic microscopy. The results showed that a greater bixin concentration resulted in higher polymeric solution electrical conductivity. Moreover, higher polymeric solution electrical conductivity provides lower nanofibers in terms of average diameter than pure PCL nanofibers. In vitro release was largely governed by a diffusion-controlled mechanism. The initial Bixin release domain showed a burst release over the first 10 hours where approximately 30% and 40% of Bixin was released from Bix-PCL1 and Bix-PCL2 nanofibers, respectively. The second kinetic domain was comprised of a continuous and slow Bixin release that led to almost 100% of the Bixin being released within 14 days. The results on excisional wound model in induced diabetic mice indicated that the low concentration of Bixin released from loaded Bix-PCL nanofibers maintain the biological activity of Bixin and is efficient in accelerating the wound healing as well as in reducing the scar tissue area compared with pure PCL nanofibers. Therefore, soft material Bixin-loaded PCL nanofibers are a promising candidate for use in wound dressing. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 1938-1949, 2017.

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Section: Methodsmentioning

confidence: 99%

Efficient cutaneous wound healing using bixin-loaded PCL nanofibers in diabetic mice

Pinzón-García

Cassini‐Vieira

Ribeiro

et al. 2016

J. Biomed. Mater. Res.

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“…Many Aborigines use annatto for dyeing, where the dye is naturally obtained as a mixture and used to color ceramics and other vases for domestic use. In addition, most endogenous people use this dye on their skin to beautify themselves during religious rituals and mainly to protect themselves from ultraviolet radiation and from mosquitoes that infest forests [ 49 ]. The bast provides fibers for rough cordage, and the powder resulting from grinding the seeds has been used as an aphrodisiac.…”

Section: Use In Traditional Medicinementioning

confidence: 99%

“…Barbosa-Filho et al [ 49 ] studied the seeds of four types of annatto cultivated in Paraíba State, Brazil, namely, “cascaverde” (“green peel”), “cascavermelha” (“red bark”), “bico de calango” (“lizard beak”), and “grãopreto”(“black grain”), with respect to their oil (material extracted with hexane) and solid (material extracted with chloroform) contents, and also pure bixin, which was obtained by successive recrystallization from the chloroform fraction. Pure bixin appears as red-purple crystals with a melting point of 196–198°C.…”

Section: Chemical Compoundsmentioning

confidence: 99%

Traditional Uses, Chemical Constituents, and Biological Activities ofBixa orellanaL.: A Review

Vilar

Moura

et al. 2014

The Scientific World Journal

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118

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Bixa orellana L., popularly known as “urucum,” has been used by indigenous communities in Brazil and other tropical countries for several biological applications, which indicates its potential use as an active ingredient in pharmaceutical products. The aim of this work was to report the main evidence found in the literature, concerning the ethnopharmacology, the biological activity, and the phytochemistry studies related to Bixa orellana L. Therefore, this work comprises a systematic review about the use of Bixa orellana in the American continent and analysis of the data collected. This study shows the well-characterized pharmacological actions that may be considered relevant for the future development of an innovative therapeutic agent.

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“…De nombreux groupes socio-culturels utilisent le colorant naturel des graines pour colorer les céramiques et d'autres ustensiles pour des usages domestiques. Ils l'utilisent aussi pour se colorer la peau pendant des rituels religieux et pour se protéger contre la lumière solaire et contre des moustiques (Barbosa-Filho et al, 1988). Les graines sont données aux taureaux pour les rendre agressifs pour des combats de taureaux et sont aussi utilisées comme laxatif, hypotensif, fluidifiant, et antimicrobien.…”

Section: Principales Voies De Valorisation De Bixa Orellanaunclassified

Le rocouyer (<i>Bixa orellana</i>), une source de biocolorant pour les industries alimentaires: revue analytique

Akakpo¹,

Badoussi²,

Gnacadja³

et al. 2019

Int. J. Bio. Chem. Sci

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Bixa orellana est une espèce végétale pourvoyeuse de biocolorant utilisé traditionnellement aussi bien en Asie, en Amérique qu'en Afrique. Cette revue vise à faire un récapitulatif des travaux antérieurs sur le colorant des graines de Bixa orellana afin de définir de nouveaux objectifs de recherche pour sa valorisation. La méthodologie adoptée est basée sur une documentation axée sur la pertinence et la qualité des articles. Une centaine d'articles scientifiques ont été exploités et les informations capitalisées font état de ce que Bixa orellana a une grande importance socioéconomique et alimentaire. Ses graines, fournissent un colorant ayant deux fractions; la norbixine (hydrosoluble) et la bixine (liposoluble), stables surtout aux températures inférieures à 180 °C et, constituent ainsi, la seule source naturelle de bixine, un caroténoïde très utilisé dans l'industrie alimentaire comme colorant. Les potentialités nutritionnelles et thérapeutiques des graines font de l'espèce, un important patrimoine agricole capable de faire face aux défis de substitution de certains colorants de synthèse par ceux de ces graines. Son exploitation permettrait de pallier aux pathologies liées à l'utilisation des colorants de synthèse, d'améliorer le revenu agricole des populations pratiquant sa culture et d'offrir à l'espèce, une visibilité pour sa valorisation en Afrique et principalement au Bénin..

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Teor de bixina em quatro variedades de Bixa orellana L. cultivadas na Paraíba

Cited by 10 publications

References 0 publications

Efficient cutaneous wound healing using bixin-loaded PCL nanofibers in diabetic mice

Efficient cutaneous wound healing using bixin-loaded PCL nanofibers in diabetic mice

Traditional Uses, Chemical Constituents, and Biological Activities ofBixa orellanaL.: A Review

Le rocouyer (<i>Bixa orellana</i>), une source de biocolorant pour les industries alimentaires: revue analytique

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