Adenocarcinoma gástrico T4b: experiência de 12 anos em Hospital Universitário

Favacho, Bernard; Costa, Carleno da Silva; Magalhães, Thamer Costa; Assumpção, Paulo Pimentel de; Ishak, Geraldo

doi:10.1590/s0102-67202013000400004

Cited by 4 publications

(4 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…They conclude that the adjuvant protocol used reduced the risk of death and relapse to three years, especially in patients with positive N1-N2 lymph nodes who underwent curative resection with D2 lymphadenectomy, but recurrence was more frequent in positive N3 lymph nodes and suggest employ new adjuvant protocols in this group of patients to decrease relapse rates. Favacho et al 12 analyzed 27 patients with staging T4b advanced gastric cancer who were only submitted to surgical treatment without adjuvant therapy and reported a 6-month survival of 63.27%.…”

Section: Discussionmentioning

confidence: 99%

Adjuvant Chemoradiotherapy After Subtotal or Total Gastrectomy and D2 Limphadenectomy Increases Survival in Advanced Gastric Cancer?

Andreollo¹,

Drizlionoks²,

Tercioti-Júnior³

et al. 2019

ABCD, arq. bras. cir. dig.

View full text Add to dashboard Cite

Background:The treatment of advanced gastric cancer with curative intent is essentially surgical and chemoradiotherapy is indicated as neo or adjuvant to control the disease and prolong survival. Aim:To assess the survival of patients undergoing subtotal or total gastrectomy with D2 lymphadenectomy followed by adjuvant chemoradiotherapy. Methods:Were retrospectively analyzed 87 gastrectomized patients with advanced gastric adenocarcinoma, considered stages IB to IIIC and submitted to adjuvant chemoradiotherapy (protocol INT 0116). Tumors of the esophagogastric junction, with peritoneal implants, distant metastases, and those that had a compromised surgical margin or early death after surgery were excluded. They were separated according to the extention of the gastrectomy and analyzed for tumor site and histopathology, lymph node invasion, staging, morbidity and survival. Results: The total number of patients who successfully completed the adjuvant treatment was 45 (51.7%). Those who started treatment and discontinued due to toxicity, tumor-related worsening, or loss of follow-up were 10 (11.5%) and reported as incomplete adjuvant. The number of patients who refused or did not start adjuvant treatment was 33 (48.3%). Subtotal gastrectomy was indicated in 60 (68.9%) and total in 27 (31.1%) and this had a shorter survival. The mean resected lymph nodes was 30.8. Staging and number of lymph nodes affected were predictors of worse survival and the more advanced the tumor. Patients undergoing adjuvant therapy with complete chemoradiotherapy showed a longer survival when compared to those who did it incompletely or underwent exclusive surgery. On the other hand, comparing the T4b (IIIB + IIIC) staging patients who had complete adjuvance with those who underwent the exclusive operation or who did not complete the adjuvant, there was a significant difference in survival. Conclusion:Adjuvant chemoradiotherapy presents survival gain for T4b patients undergoing surgical treatment with curative intent.

show abstract

Section: Discussionmentioning

confidence: 99%

Adjuvant Chemoradiotherapy After Subtotal or Total Gastrectomy and D2 Limphadenectomy Increases Survival in Advanced Gastric Cancer?

Andreollo¹,

Drizlionoks²,

Tercioti-Júnior³

et al. 2019

ABCD, arq. bras. cir. dig.

View full text Add to dashboard Cite

show abstract

“…Embora os procedimentos médicos e tecnológicos tenham avançado significativamente, somente uma taxa inferior a 30% dos indivíduos acometidos por câncer gástrico conseguem atingir um período de sobrevida superior a 5 anos 12 .…”

Section: Issn 2236-5834unclassified

Tendência de Mortalidade por Câncer Gástrico no Nordeste Brasileiro

2021

View full text Add to dashboard Cite

Objetivo: Este estudo tem como objetivo elucidar o perfil de mortalidade por câncer gástrico na região do Nordeste brasileiro, entre os anos de 2000 a 2018. Método: Trata-se de um estudo epidemiológico retrospectivo realizado por meio da recuperação de dados secundários de mortalidade por câncer gástrico na região Nordeste, disponíveis no Atlas On-line de Mortalidade, no site do Instituto Nacional de Câncer. Resultados: No período analisado, foram registrados 50.935 óbitos, sendo 2018 o ano com maior número de óbitos (6,9%). Os estados que apresentaram mais óbitos foram Ceará (24,7%), Bahia (23,4%) e Pernambuco (17,5%). O perfil foi composto predominantemente por indivíduos do sexo masculino (62%), com idades entre 70 a 79 anos (25,9%). Houve associação estatisticamente positiva entre homens e as faixas etárias de 20 a 29 anos, 30 a 39 anos, 40 a 49 anos e acima de 80 anos e entre mulheres e as faixas etárias de 50 a 59 anos de idade, 60 a 69 anos e 70 a 79 anos (p 0,001). Conclusão: Mediante ao exposto, verifica-se que as taxas de mortalidade por câncer gástrico nesta região são consideravelmente elevadas e estão associadas, principalmente, ao diagnóstico tardio da doença. Assim, destaca-se a importância da realização de ações de rastreamento e diagnóstico precoce e a necessidade de avanço dos tratamentos, visando proporcionar melhores prognósticos e atenuação da mortalidade.

show abstract

“…On the low family income found, studies based on data from educational, family income or occupation census data have consistently shown the association between stomach cancer and low socioeconomic status, where the rate in low--level individuals may be two to three times higher than in the higher classes. 10 In the low socioeconomic groups, the incidence of gastric cancer and the mortality rate are three times higher than in the high socioeconomic level due to eating habits, environmental and social factors, and clinics. 4 Regarding the caregivers' knowledge, it is noticed that there is a great stigma applied to cancer, as a disease usually associated with death.…”

Section: Health Promotion Actions For the Prevention Of Gastric Cancementioning

confidence: 99%

“…12 On the other hand, the socioeconomic level by itself should not increase the risk of stomach cancer, however, it should be associated with several risk factors, such as salt consumption and H. pylori infection. 10 H. pylori infection is considered the main risk factor for gastric adenocarcinoma. 17 Consuming fruits daily has seen a 75% reduction in the risk of gastric cancer, and fruit has a favorable effect against gastric cancer.…”

Section: Health Promotion Actions For the Prevention Of Gastric Cancementioning

confidence: 99%

Caregivers’ Knowledge Concerning The Gastric Cancer Prevention / Conhecimento de Cuidadores Sobre Prevenção do Câncer Gástrico

Mendes

Santana

2019

R. pesq. cuid. fundam. online

View full text Add to dashboard Cite

Objective:The study's purpose has been to scrutinize the knowledge of caregivers of patients bearing gastric cancer, to identify the main risk factors in caregivers and to propose actions of health education among caregivers regarding the gastric cancer. Methods: It is a descriptive study with a qualitative approach. Data collection was carried out through a semi-structured interview with caregivers of patients with gastric cancer. Data analysis was performed according to Bardin's perspective. Results: The interviewees had insufficient knowledge about the prevention of gastric cancer, then leading to unhealthy habits that compromise their health. Conclusion: It is necessary to implement educational engagement at all levels of health care, furthermore, it is the responsibility of professionals to disseminate knowledge about the subject, as well as it is up to users to choose behaviors that produce health rather than habits that lead to illnesses.

show abstract

Adenocarcinoma gástrico T4b: experiência de 12 anos em Hospital Universitário

Cited by 4 publications

References 16 publications

Adjuvant Chemoradiotherapy After Subtotal or Total Gastrectomy and D2 Limphadenectomy Increases Survival in Advanced Gastric Cancer?

Adjuvant Chemoradiotherapy After Subtotal or Total Gastrectomy and D2 Limphadenectomy Increases Survival in Advanced Gastric Cancer?

Tendência de Mortalidade por Câncer Gástrico no Nordeste Brasileiro

Caregivers’ Knowledge Concerning The Gastric Cancer Prevention / Conhecimento de Cuidadores Sobre Prevenção do Câncer Gástrico

Contact Info

Product

Resources

About