Estudo comparativo das alterações jejunais e colônicas com a interposição gastrojejunoduodenal e gastrocoloduodenal em cães

Abstract

-Background -The intestinal interpositions are important in various operations of the digestive tract. However, they are capable to produce serious immediate and late complications. Aim -To compare clinical and surgical outcomes, as well as intestinal pathological findings, in dogs submitted to jejunum and colon interposition. Methods -Forty male mongreal dogs were immunized and dewormed, between 36 and 72 months old and weighting from 6 to 16 kg divided into two groups of 20 (G1=gastrojejunoduodenal and G2=gastrocoloduodenal). They were anesthetized and submitted to laparotomy with jejunum and colon interposition between the gastric antrum and the duodenum. On the 120 th postoperative day, a relaparotomy was performed with removal of the jejunun/colon segments for evaluation. The segments were processed using Bouin and tissue were stained with H&E for histological analysis. Clinical and surgical outcomes analyzed were weight, diarrhea, fistula, infection, suture dehiscence and incisional hernia. The pathological analysis involved neutrophilic infiltration, increase in number of goblet cells and villous and crypts hypotrophy. Mann-Whitney and Fisher Exact tests were used for groups comparisons. Results -Dogs that underwent gastrocoloduodenal interposition had a higher weight loss (p<0.05) and more diarrhea (p<0.001). Clinically, controlled fistula rates were 20% in G1 and 100% in G2. Complications occurred in 20% in G1 and in all animals in G2 (p<0.001). Pathological alterations were also more prevalent in G2 (p<0.001). Conclusion -There is a high morbidity and complication rates involving intestine interposition and higher in G2 where colon segments were used. RESUMO -Racional -As interposições intestinais são importantes em diversasoperações do tubo digestivo. Contudo, são passíveis de complicações imediatas e tardias. Objetivo -Comparar as interposições com segmentos de jejuno e de colo em cães, quanto à evolução clínica e cirúrgica e aspecto anatomopatológico dos segmentos interpostos. Métodos -Foram utilizados 40 cães sem raça definida, imunizados e vermifugados, machos, idade entre 36 e 72 meses, peso entre 6 e 16 kg distribuídos em dois grupos de 20 (G1=gastrojejunoduodenal e G2=gastrocoloduodenal). Submeteram-se à lapatoromia para interposição de jejuno e de colo entre o antro gástrico e o duodeno. Após 120 dias, foi realizada relaparotomia para remoção dos segmentos de jejuno e de colo e analisados pelo método Bouin e cortes histológicos corados por H&E para estudo anatomopatológico. Os resultados clínicos e cirúrgicos analisados foram peso, diarréia, fístulas, infecção, deiscência de sutura e hérnia incisional. A análise patológica envolveu infiltração de neutrófilos, aumento do número de células caliciformes e das vilosidades e hipotrofia de criptas. Os testes de Mann-Whitney e Exato de Fisher foram utilizados na comparação entre os grupos. Resultados -Os cães submetidos à interposição gastrocoloduodenal produziram mais perda de peso (p<0,05) e diarreia (p<0,001). A taxa de fístula clínica fo...

The effect of cashew leaf extract on small intestine morphology and growth performance of Jawa Super chicken

“…The length of the intestine was measured, and the duodenum, ileum, and jejunum of the small intestine were then separated. Each organ was inserted into Bouin’s solution for histological preparation [ 8 , 9 ].…”