A doença meningocócica em São Paulo, Brasil, no século XX: características epidemiológicas

Moraes, José Cássio de; Barata, Rita Barradas

doi:10.1590/s0102-311x2005000500019

Cited by 32 publications

(45 citation statements)

References 11 publications

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“…Therefore, any delay in reaching diagnosis and in receiving medical attention may be crucial and may lead to an unfavorable outcome. Furthermore, it should be emphasized that it is in the most underprivileged sectors of society that the majority of deaths occur, strengthening the hypothesis that the difficulty experienced by these populations in receiving prompt medical attention constitutes an important factor for this outcome, since fatality is a valuable indicator of medical care in meningococcal disease 24 .…”

Section: Conflict Of Interest Referencesmentioning

confidence: 96%

“…Although meningococcal meningitis affects all social classes, its intensity varies according to the different socioeconomic strata of the population, with some authors reporting higher rates associated with precarious living conditions 24 . In practice, living conditions represent a valuable criterion for identifying determinants of epidemiological differences related to the occupation of a geographical social space 25 , since the spatial pattern of a city is also defined by social relationships 26 .…”

Section: Souza Sf Et Al -Bacterial Meningitismentioning

confidence: 99%

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Bacterial meningitis and living conditions

Souza

Costa

Paim

et al. 2012

Rev. Soc. Bras. Med. Trop.

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Introduction: Bacterial meningitis has great social relevance due to its ability to produce sequelae and cause death. It is most frequently found in developing countries, especially among children. Meningococcal meningitis occurs at a high frequency in populations with poor living conditions. This study describes the temporal evolution of bacterial meningitis in Salvador, Brazil, 1995, and verifies the association between its spatial variation and the living conditions of the population. Methods: This was an ecological study in which the areas of information were classified by an index of living conditions. It examined fluctuations using a trend curve, and the relationship between this index and the spatial distribution of meningitis was verified using simple linear regression. Results: From 1995-2009, there were 3,456 confirmed cases of bacterial meningitis in Salvador. We observed a downward trend during this period, with a yearly incidence of 9.1 cases/100,000 population and fatality of 16.7%. Children aged <5 years old and male were more affected. There was no significant spatial autocorrelation or pattern in the spatial distribution of the disease. The areas with the worst living conditions had higher fatality from meningococcal disease (β = 0.0078117, p < 0.005). Conclusions: Bacterial meningitis reaches all social strata; however, areas with poor living conditions have a greater proportion of cases that progress to death. This finding reflects the difficulties for ready access and poor quality of medical care faced by these populations.

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Section: Conflict Of Interest Referencesmentioning

confidence: 96%

Section: Souza Sf Et Al -Bacterial Meningitismentioning

confidence: 99%

Bacterial meningitis and living conditions

Souza

Costa

Paim

et al. 2012

Rev. Soc. Bras. Med. Trop.

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“…As sequelas acometem de 11% a 19% dos sobreviventes 3 . As crianças menores de cinco anos apresentam maior risco de óbito, enquanto a letalidade se mostra mais elevada nas faixas etárias extremas 1,4,5 .…”

Section: Introductionunclassified

“…A doença meningocócica é endêmica nas grandes metrópoles brasileiras 2,4,13 . O Municí-pio de São Paulo sofre frequentes ondas epidê-micas, não raramente é observada a sobreposição de epidemias de dois sorogrupos.…”

Section: Introductionunclassified

“…O Municí-pio de São Paulo sofre frequentes ondas epidê-micas, não raramente é observada a sobreposição de epidemias de dois sorogrupos. Na década de 1970, por exemplo, o Município de São Paulo vivenciou epidemias simultâneas pelos sorogrupos A e C 14 , e na de 1990, pelos sorogrupos B e C, atingindo taxas de incidência de 8 e de mortalidade de 1,5/100 mil habitantes/ano 4 .…”

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Mortalidade por doença meningocócica no Município de São Paulo, Brasil: características e preditores

et al. 2015

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O estudo objetiva descrever a magnitude, as características da mortalidade e da letalidade por doença meningocócica e investigar preditores de óbito por essa causa, no Município de São Paulo, Brasil, de 1986 a 2004. Utilizou-se a regressão logística múltipla não condicional para a investigação dos preditores de óbitos. Foram estudados 10.087 casos de doença meningocócica no município. A taxa anual média de mortalidade foi de 1,0/100 mil habitantes/ano, variando de 0,2 a 1,8; a letalidade foi de 20,5% com grandes diferenças segundo idade, sorogrupo e tipo de hospital. Os preditores de óbito por doença meningocócica foram idade, especialmente as faixas etárias de um a dois anos e de 40 anos ou mais e o sorogrupo W. Os resultados obtidos podem contribuir para a elaboração de políticas públicas com foco na organização da assistência hospitalar e elaboração de protocolos que promovam a maior efetividade do tratamento e a aplicação de estratégias de vacinação que diminuam a incidência nos grupos de maior risco para óbito por doença meningocócica.

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Meningococcal disease before and after the introduction of meningococcal serogroup C conjugate vaccine. Federal District, Brazil

Tauil

Carvalho

Vieira

et al. 2014

The Brazilian Journal of Infectious Diseases

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A doença meningocócica em São Paulo, Brasil, no século XX: características epidemiológicas

Abstract: This study analyzes the epidemiological behavior of meningococcal disease in the city of São Paulo, Brazil, over the course of the 20 th century. Applying data from patient records, death cer

Cited by 32 publications

References 11 publications

Bacterial meningitis and living conditions

Bacterial meningitis and living conditions

Mortalidade por doença meningocócica no Município de São Paulo, Brasil: características e preditores

Meningococcal disease before and after the introduction of meningococcal serogroup C conjugate vaccine. Federal District, Brazil

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