Fifty years in the blink of an eye: a retrospective study of ocular and periocular lesions in domestic animals

Abstract

Pesq. Vet. Bras. 34(12):1215-1222, dezembro 2014 1215 RESUMO.-[Cinquenta anos num piscar de olhos: um estudo retrospectivo sobre lesões oculares e perioculares em animais domésticos.] Foi realizada uma investigação para obter-se uma visão geral das lesões oculares e perioculares de mamíferos domésticos diagnosticadas ao longo de um período de 50 anos num laboratório de diagnóstico de patologia veterinária da Região Central do Rio Grande do Sul. Nesse laboratório, durante o período pesquisado foram realizados 33.075 exames histopatológicos, 540 dos quais (1,6%) eram de lesões oculares e perioculares. Por várias razões, 90 espécimes foram excluídos do estudo. As 450 amostras restantes consistiam espécimes de cães (53,5%), bovinos (28,2%), gatos (11,1%), cavalos (5,1%), ovelhas (1,3%), coelhos (0,4%), e porco (0,2% A survey was undertaken aiming to obtain an overview of ocular and periocular lesions diagnosed in domestic mammals over a period of 50 years in a veterinary pathology diagnostic laboratory in the Central Region of the State of Rio Grande do Sul, Brazil. In this lab, 33,075 histophatological exams had been performed over the period surveyed, of which 540 (1.6%) concerned ocular and periocular lesions. For various reasons ninety specimens were excluded from the study and the remaining 450 consisted of samples from dogs (53.5%), cattle (28.2%), cats (11.1%), horses (5.1%) sheep (1.3%), rabbits (0.4%), and pig (0.2%). The eyelids were the most prevalent (248/450) site of lesions in each of the species studied, followed by third eyelid (73/450), and conjunctiva (27/450). In dogs (241 samples) lesions in sebaceous glands (including Meibomian glands) were the most common findings (75/241), followed by melanocytic tumors (52/241) and nonspecific conjunctivitis (13/241). Squamous cell neoplasms, both benign and malignant, were relatively common. In cattle, anatomical sites affected by ocular and periocular lesions, in decreasing order of frequency, were eyelid, cornea and third eyelid. Squamous cell carcinoma (SCC) alone accounted for 80.3% of all diagnoses, while all neoplastic lesions made up for 85.0% of the lesions diagnosed in cattle. Neoplasia accounted for most of the lesions diagnosed in cats (39/50 cases); all of these were malignant, and SCC, hemangiosarcoma and fibrosarcoma were the most common types diagnosed. In horses, 19 out of 23 submissions were neoplasms and most were sarcoid (8/23) and SCC (8/23). There were six submissions from sheep with unpigmented skin, all of which represented SCC of the eyelids (5) and third eyelid (1).

Retrobulbar Fibrosarcoma in a Sheep

“…Ocular pathology is a new area of veterinary medicine that studies pathological processes that affect the eye bulb and its adnexal structures [5]. One of the most common pathologies of the eyes tumors and they are generally seen in cats and dogs [10].…”

“…One of the most common pathologies of the eyes tumors and they are generally seen in cats and dogs [10]. Ovine ocular neoplasms are in general quite uncommon [1,5]. The most common ocular tumor reported in sheep is squamous cell carcinoma [1,2].…”

“…Squamous cell carcinoma was the predominant type of eyelid neoplasm in cattle, cats and sheep while melanocytic tumors are commonly seen in dogs [1][2][3][4][5][6][7]. Ocular fi brosarcomas may develop in the orbit of cats with pthysis bulbi, ocular trauma or ocular foreign bodies [8].…”

Prospective study of ocular and periocular diseases in animals: 188 cases

“…Thus, frequency studies of ocular pathology alterations are rare in Brazil. Of 33,075 histopathologic evaluations in a 50-year retrospective study conducted in Southern Brazil, only 1,63% were of ocular or periocular lesions (Martins & Barros 2014). Another study was also conducted in Southern Brazil, focused mainly on ocular and periocular neoplastic diseases of cats and dogs (Hesse et al 2015).…”

Caracterização clínica e histopatológica de bulbos oculares de cães e gatos (2005-2015)

“…Este estudo relacionou os diagnósticos clínicos dos animais submetidos à remoção cirúrgica do bulbo diretamente com seus respectivos diagnósticos histopatológicos; os bulbos analisados foram exclusivamente provenientes de enucleações e exenterações realizadas pelo serviço supracitado. Em alguns estudos no Brasil foi realizada a análise patológica de afecções oculares em animais domésticos (cães, gatos, ruminantes e equinos), tais como neoplasias oculares e glaucoma (Martins & Barros 2014, Hesse et al 2015, no entanto, em um dos estudos foram avaliadas afecções perioculares e intraoculares, na outra pesquisa as amos- …”