Doença das mucosas associada à dermatite generalizada em bovinos, Mato Grosso do Sul

Ferreira, Luiz C.L.; Flores, Eduardo Furtado; Driemeier, David; Melo, Orivaldo; Lemos, Ricardo A.A.

doi:10.1590/s0100-736x2008000600005

Cited by 7 publications

(9 citation statements)

References 24 publications

(25 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Generalized dermatitis has been observed in cattle infected by BVDV (Ferreira et al 2008), yet teat lesions have not been described. Infection by BoHV-2 causes herpes mammilitis and lesions affect frequently the teats of lactating cows and include swollen and painful lesions, 1-2cm diameter plaques, ulcers and crusts.…”

Section: Discussionmentioning

confidence: 99%

Outbreaks of vesicular disease caused by Vaccinia virus in dairy cattle from Goiás State, Brazil (2010-2012)

Sant’Ana

Leal²,

Rabelo³

et al. 2013

Pesq. Vet. Bras.

View full text Add to dashboard Cite

Pesq. Vet. Bras. 33 (7) Midwestern Brazil (2010, involving a total of 122 cows, 12 calves and 11 people. Dairy cows (3 to 9 years old) were affected in all cases and calves (2 to 9 months old) were affected in five outbreaks, presenting oral lesions. The morbidity ranged between 8 and 100% in cows, and 1.5 to 31% in calves. In the cows, the clinical signs started with vesicles (2-7mm), painful and coalescent papules (3-8 mm), which resulted in ulcers (5-25mm) and scabs in teats, and, occasionally, in the muzzle. The clinical course lasted from 16 to 26 days. The histopathology of bovine skin samples revealed superficial perivascular inflammatory infiltrate of lymphocytes, plasma cells, neutrophils, macrophages and multifocal areas of acanthosis, spongiosis, hipergranulosis and parakeratotic or orthokeratotic hyperkeratosis with adjacent focally extensive ulcers. Eosinophilic inclusion bodies were noted in the cytoplasm of the keratinocytes. PCR to vgf gene of Orthopoxvirus was positive in samples collected from all outbreaks, and in some cases, genomic VACV sequences were identified by nucleotide sequencing of the PCR amplicons. Infectious virus was isolated in cell culture from scabs from one outbreak. Antibodies to Orthopoxvirus were detected in at least 3 or 4 animals in most outbreaks, by ELISA (outbreaks 1, 2, 3, 4, 5 and 7) or virus-neutralization (outbreak 6). Neutralizing titers ranging from 8 to 64 in outbreak 6. In all outbreaks, VACV infection was suspected based on the clinical and pathological findings and it was confirmed by laboratory tests. Upon the etiological confirmation, other agents associated with vesicular disease were discarded. In all outbreaks, at least one milker who handled the affected cows developed malaise, headache, fever, painful vesico-pustular lesions mainly in the hands, but also in the neck and nose. These results confirm the circulation of VACV in the region and call attention for a correct diagnosis and the adoption of prophylactic and control measures.

show abstract

Section: Discussionmentioning

confidence: 99%

Outbreaks of vesicular disease caused by Vaccinia virus in dairy cattle from Goiás State, Brazil (2010-2012)

Sant’Ana

Leal²,

Rabelo³

et al. 2013

Pesq. Vet. Bras.

View full text Add to dashboard Cite

show abstract

“…Gross skin lesions associated with BVDV are described as localized lesions in chronically affected MD animals with ulceration of the interdigital cleft and coronary band [11] but might also present as generalized dermatitis in cattle with a clinical course of 30 to 45 days [13,14]. However, all of the cattle included in the present study presented an acute clinical course, with a maximum of 20 days, similar to the findings observed in a similar MD animal infected with BHoBi^-like Pestivirus, which showed a clinical course of 15 to 20 days [20].…”

Section: Discussionmentioning

confidence: 99%

“…BVDV lesions may occur with BVDV infection depending on host factors, such as the immune competence and immune status, and viral factors, such as the genotype/subgenotype, biotype, and virulence of the infecting strain [7]. Dermatitis is frequently present in mucosal disease (MD) [10] and might present as localized lesions in chronically affected MD animals with ulceration of the interdigital cleft and coronary band [11] or as generalized acute or chronic dermatitis [12,13]. Additionally, generalized dermatitis might be observed in PI animals infected with ncp-BVDV [14].…”

Section: Introductionmentioning

confidence: 99%

Pathological and virological features of skin lesions caused by BVDV in cattle

et al. 2018

Self Cite

View full text Add to dashboard Cite

Dermatitis might occur in mucosal disease (MD) caused by bovine viral diarrhea virus (BVDV). This study describes the pathological and virological features of skin lesions associated with BVDV infection in four persistently infected (PI) cattle. Skin samples were reprocessed for histopathology and IHC. BVDV isolates were obtained and were genetically characterized. In addition to upper alimentary system ulcerative lesions, all cattle (one outbreak and three individual cases) presented focal crusty and ulcerative lesions affecting the mucocutaneous and skin-horn junctions, interdigital clefts, pastern, and areas surrounding the dewclaws and diffuse thickened skin within 7-20 days of infection. Microscopic analysis revealed parakeratotic hyperkeratosis and single-cell keratinocyte death, accompanied by ballooning degeneration and spongiosis in the epidermis, as well as intraepithelial and subcorneal pustules. IHC showed BVDV antigen in the cytoplasm of keratinocytes undergoing individual cell death. Phylogenetic analysis revealed that the isolates from cattle #1, #2, and #4 belonged to BVDV-1a, whereas that from cattle #3 belonged to BVDV-1d. Cytopathic BVDV was isolated from cattle #2 and #3 (MD), and non-cytopathic BVDV was isolated from cattle #1 and #4. Thus, BVDV infection might cause acute disease, characterized by skin and upper alimentary system ulcerative lesions, in both MD and PI cattle.

show abstract

“…In pregnant animals the disease causes various reproductive disorders: early embryonic death, abortions, mummified foetuses, foetal malformations, stillbirths, birth of weak and nonvital calves (34). Embryos infected between the 60 th and 90 th gestational days are born as immunotolerant and persistently infected (PI) calves (35).…”

Section: Bovine Viral Diarrhoea -Mucosal Diseasementioning

confidence: 99%

Pathomorphological Aspects of Relevant Gastrointestinal Diseases in Newborn and Growing Calves

Kalkanov¹,

Dinev²

2019

TJS

View full text Add to dashboard Cite

The emphasis of this literature overview is placed on the etiology, epidemiology, specific gross and microscopic pathological changes of the commonest gastrointestinal diseases in newborn and growing calves in dairy and beef farms. Neonatal diarrhea in calves is a multifactorial disease accompanied with high morbidity and mortality rates. It incurs considerable economic losses for cattle industry worldwide. The gastroenteritis in calves is most commonly of infectious or parasitic etiology and the most frequently involved enteropathogens are Cryptosporidium parvum, bovine rotaviruses (GRA BRV), bovine coronaviruses (BCoV), mucosal disease virus - bovine viral diarrhoea (BVDV) and Escherichia coli K99 (F5). Affected calves are from 24th hours to 30 days of age, and the appearance of the disease is largely dependent on the immunological status of newborn calves, the amount of ingested colostrum, whether dams are vaccinated or not during the dry period, and the conditions of housing of newborns. The specific gross and microscopic lesions of the gastrointestinal tract and of some parenchymal organs are essential for the diagnostics and differential diagnostics of reviewed diseases.

show abstract

Doença das mucosas associada à dermatite generalizada em bovinos, Mato Grosso do Sul

Cited by 7 publications

References 24 publications

Outbreaks of vesicular disease caused by Vaccinia virus in dairy cattle from Goiás State, Brazil (2010-2012)

Outbreaks of vesicular disease caused by Vaccinia virus in dairy cattle from Goiás State, Brazil (2010-2012)

Pathological and virological features of skin lesions caused by BVDV in cattle

Pathomorphological Aspects of Relevant Gastrointestinal Diseases in Newborn and Growing Calves

Contact Info

Product

Resources

About