Constituintes químicos de Solanum buddleifolium Sendtn

Pinto, Francisco das Chagas L.; Torres, Maria da Conceição M.; Silveira, Edilberto R.; Pessoa, Otília Deusdênia Loiola; Braz‐Filho, Raimundo; Guédès, Michel

doi:10.1590/s0100-40422013000800006

Cited by 11 publications

(7 citation statements)

References 13 publications

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“…Lignans are rare in the genus Solanum [ 79 ], with only 31 compounds ( 414 – 444 ) having been isolated (Fig. 9 ).…”

Section: Chemical Constituents and Their Biological Propertiesmentioning

confidence: 99%

“…9 ). Compounds 414 – 419 were obtained from the stems of S. buddleifolium [ 79 ], while 424 – 432 , 434 and 442 were isolated from the roots of S. melongena [ 208 – 210 ]. Several neo-lignans, sisymbrifolin ( 433 ) from the fruits of S. sisimbriifolium [ 519 ], ficusal ( 442 ) from the roots of S. melongena [ 209 ], glycosmisic acid ( 439 ), simulanol ( 440 ) and balanophonin ( 443 ) from the whole plant of S. surattense [ 518 ] were identified.…”

Section: Chemical Constituents and Their Biological Propertiesmentioning

confidence: 99%

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The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review

Kaunda

Zhang

2019

Nat. Prod. Bioprospect.

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Over the past 30 years, the genus Solanum has received considerable attention in chemical and biological studies. Solanum is the largest genus in the family Solanaceae, comprising of about 2000 species distributed in the subtropical and tropical regions of Africa, Australia, and parts of Asia, e.g., China, India and Japan. Many of them are economically significant species. Previous phytochemical investigations on Solanum species led to the identification of steroidal saponins, steroidal alkaloids, terpenes, flavonoids, lignans, sterols, phenolic comopunds, coumarins, amongst other compounds. Many species belonging to this genus present huge range of pharmacological activities such as cytotoxicity to different tumors as breast cancer (4T1 and EMT), colorectal cancer (HCT116, HT29, and SW480), and prostate cancer (DU145) cell lines. The biological activities have been attributed to a number of steroidal saponins, steroidal alkaloids and phenols. This review features 65 phytochemically studied species of Solanum between 1990 and 2018, fetched from SciFinder, Pubmed, ScienceDirect, Wikipedia and Baidu, using “Solanum” and the species’ names as search terms (“all fields”).

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“…Lignans are rare in the genus Solanum [ 79 ], with only 31 compounds ( 414 – 444 ) having been isolated (Fig. 9 ).…”

Section: Chemical Constituents and Their Biological Propertiesmentioning

confidence: 99%

Section: Chemical Constituents and Their Biological Propertiesmentioning

confidence: 99%

The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review

Kaunda

Zhang

2019

Nat. Prod. Bioprospect.

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“…Known compounds isolated from P. puberulum include semiimmersumine B ( 12 ), liriodenine ( 13 ), norcepharadione B ( 14 ), piperolactam A ( 15 ), piperolactam C ( 16 ), aristololactam II ( 17 ), aduncamide ( 18 ), houttuynamide A ( 19 ), N - cis -feruloytyramine ( 20 ), N - trans -feruloyltyramine ( 21 ), paprazine ( 22 ), deca-2 E ,4 E -dienoic acid isobutylamide ( 23 ) semiimmersumine A ( 24 ), piperolactam B ( 25 ), cepharanone ( 26 ), N - cis -sinapoyltyramine ( 27 ), N - trans -sinapoyltyramine ( 28 ), N - trans -feruloil-3′- O -metoxidopamina ( 29 ), 1,2-dihydro-6,8-dimethoxy-7-hydroxy-1-(3,5-dimethoxy-4-hydroxyphenyl)- N l , N 2 -bis-[2-(4-hydroxyphenyl)ethyl]-2,3-naphthalene dicarboxamide ( 30 ), and 1-( m -methoxycinnamoyl)pyrrolidine ( 31 ), identified by comparison with literature data.…”

Section: Results and Discussionmentioning

confidence: 99%

New Tyramine- and Aporphine-Type Alkamides with NO Release Inhibitory Activities from Piper puberulum

Zheng

Wang

et al. 2021

J. Nat. Prod.

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Three new tyramine-type alkamides (1–3), three new natural products (4–6), five new N-acylated/formylated aporphine alkamides with different ratios of rotational isomers (7–11), and 20 known alkamides (12–31) were isolated from an EtOH extract of the stems and leaves of Piper puberulum. The absolute configurations of compounds 7, 8, and 10 were determined by single-crystal X-ray diffraction analysis. In the biological activity assay, compounds 3, 5, and 10–23 displayed inhibitory effects against lipopolysaccharide-induced NO release in BV-2 microglial cells, exhibiting IC50 values of 0.93–45 μM.

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“…From the group of lignans, two isomers of alangilignoside C were identified (63 and 64). Alangilignoside C was a common compound in the genus Solanum, and it was detected in the EtOH stem extract of Solanum buddleifolium [48]. Additionally, pinoresinol (67) and its hexosyl derivatives (66), isolariciresinol-3-O-hexoside (65), and syringaresinol (68) were found.…”

Section: Tissue-specific Distribution Of Polyphenolics In Mg and Rr B...mentioning

confidence: 99%

Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening

et al. 2023

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The present study provides, for the first time, a physicochemical and biochemical characterization of the redox processes associated with the ripening of Solanum dulcamara L. (bittersweet) berries. Electron Paramagnetic Resonance Spectroscopy (EPRS) and Imaging (EPRI) measurements of reactive oxygen species (ROS) were performed in parallel with the tissue-specific metabolic profiling of major antioxidants and assessment of antioxidant enzymes activity. Fruit transition from the mature green (MG) to ripe red (RR) stage involved changes in the qualitative and quantitative content of antioxidants and the associated cellular oxidation and peroxidation processes. The skin of bittersweet berries, which was the major source of antioxidants, exhibited the highest antioxidant potential against DPPH radicals and nitroxyl spin probe 3CP. The efficient enzymatic antioxidant system played a critical protective role against the deleterious effects of progressive oxidative stress during ripening. Here, we present the EPRI methodology to assess the redox status of fruits and to discriminate between the redox states of different tissues. Interestingly, the intracellular reoxidation of cell-permeable nitroxide probe 3CP was observed for the first time in fruits or any other plant tissue, and its intensity is herein proposed as a reliable indicator of oxidative stress during ripening. The described noninvasive EPRI technique has the potential to have broader application in the study of redox processes associated with the development, senescence, and postharvest storage of fruits, as well as other circumstances in which oxidative stress is implicated.

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Constituintes químicos de Solanum buddleifolium Sendtn

Cited by 11 publications

References 13 publications

The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review

The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review

New Tyramine- and Aporphine-Type Alkamides with NO Release Inhibitory Activities from Piper puberulum

Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening

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