Ésteres triterpênicos de Himatanthus sucuuba (Spruce) Woodson

Silva, Jefferson Rocha de Andrade; Rezende, Cláudia M.; Pinto, Ângelo C.; Pinheiro, Maria Lúcia B.; Cordeiro, M. C.; Tamborini, E.; Young, Cláudia M.; Bolzani, Vanderlan da Silva

doi:10.1590/s0100-40421998000600005

Cited by 32 publications

(26 citation statements)

References 19 publications

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“…The triterpenes 1-6 were identified by comparison of their NMR data with the literature (Fulgentius et al, 1990;Klass & Tinto, 1992;Silva et al, 2000;Souza et al, 2001;Saraiva et al, 2006). Biological activities were previously reported for the isolated triterpenes: anti-AIDS for betulinic acid, herbicid for lupenone and fibrinolytic for betulin (Connolly & Hill, 2010).…”

Section: Resultsmentioning

confidence: 99%

Triterpenes and flavonoids from the roots of Mauritia flexuosa

Koolen¹,

Soares²,

Silva³

et al. 2012

Rev. bras. farmacogn.

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Mauritia flexuosa L. f., Arecaceae, is an endemic species of South America. This species was studied with the intent to isolate the constituents of its roots. After the fractionation of the n-hexane and methanolic extracts from the roots of M. flexuosa, six triterpenes were obtained: friedelin, taraxerone, lupenyl acetate, lupenone, betulin and betulinic acid, along with three flavonoids: rutin, quercitrin and quercetin. All the compounds were identified by analysis of NMR and MS data and comparison with the literature. All those compounds are been reported for the first time in Mauritia, and the chemosystematic significance of the flavonoids isolated in this genus is discussed.

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Section: Resultsmentioning

confidence: 99%

Triterpenes and flavonoids from the roots of Mauritia flexuosa

Koolen¹,

Soares²,

Silva³

et al. 2012

Rev. bras. farmacogn.

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“…Os alcaloides indólicos dos representantes do gênero apresentam diversas atividades farmacológicas, entre elas antimicrobiana (Silva et al, 1998;Neto et al, 2002;Morel et al, 2006), antitumoral (Wood et al, 2001), antiprotozoária (Deharo et al, 2001;Mesquita et al, 2005;Castillo et al, 2007) e anti-inflamatória (Miranda et al, 2000). Himatanthus lancifolius (Müll.…”

Section: Introductionunclassified

Himatanthus lancifolius (Müll. Arg.) Woodson, Apocynaceae: estudo farmacobotânico de uma planta medicinal da Farmacopeia brasileira 1ª edição

Baratto¹,

Hohlemwerger²,

Guédès³

et al. 2010

Rev. bras. farmacogn.

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RESUMO:Himatanthus lancifolius (Müll. Arg.) Woodson é um arbusto nativo do Brasil, latescente, popularmente conhecido como agoniada e utilizado principalmente para distúrbios menstruais. O presente trabalho teve como objetivo caracterizar morfoanatomicamente a folha, o caule e a casca caulinar dessa planta medicinal, a fim de contribuir para o controle de qualidade e a autenticidade dessa espécie. O material vegetal foi fixado e submetido às microtécnicas usuais. A folha é simples, glabra e obovado-lanceolada. A epiderme é uniestratificada, revestida por cutícula estriada e possui estômatos anisocíticos na face abaxial. O mesofilo é dorsiventral. A nervura central é biconvexa e o pecíolo é circular, ambos apresentando feixes vasculares bicolaterais. Laticíferos, amiloplastos e idioblastos fenólicos estão presentes no parênquima fundamental da nervura central e do pecíolo. O sistema vascular do caule é tipicamente bicolateral. Laticíferos e idioblastos fenólicos ocorrem no córtex, no floema e na medula. Esses caracteres morfoanatômicos, em conjunto, podem ser utilizados como parâmetros para o controle de qualidade dessa espécie.Unitermos: Apocynaceae, floema interno, Himatanthus lancifolius, laticíferos, morfoanatomia.ABSTRACT: "Himatanthus lancifolius (Müll. Arg.) Woodson, Apocynaceae: morphoanatomical study of a medicinal plant described in the Brazilian Pharmacopoeia 1st edition". Himatanthus lancifolius (Müll. Arg.) Woodson is a Brazilian native shrub, laticiferous, popularly known as "agoniada". It is mainly used for uterine disorders. The present work aimed to study the leaf, stem and stem bark morpho-anatomy of this medicinal plant, in order to contribute to its quality control and identification. The plant material was fixed and submitted to standard microtechniques. The leaf is simple, glabrous and obovate-lanceolate. The epidermis is uniseriate, coated with striated cuticle and it has anysocitic stomata on the abaxial surface. The mesophyll is dorsiventral. The midrib is biconvex and the petiole is circular, both present bicollateral vascular bundles. Laticiferous ducts, amyloplasts and phenolic idioblasts are found in ground parenchyma of the midrib and petiole. The vascular system of the stem is tipically bicollateral. Laticiferous ducts and phenolic idioblasts are present in the cortex, phloem and pith. These morpho-anatomical characters, all together, can be used as quality control parameters of this species.

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“…In Brazil, the latex and bark have been used as an antitumor agent and for their antiulcer and anti-inflammatory activities (Schultes, 1979;van den Berg, 1982;Di Stasi et al, 1989;Silva et al, 1998). However there is limited pharmacology reported to justify, in terms of existing legal requirements, the wide use of the plant by the population.…”

Section: Introductionmentioning

confidence: 99%

Quantitative determination by HPLC of iridoids in the bark and latex of himatanthus sucuuba

et al. 2007

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The main iridoids from the bark and latex of Himatanthus sucuuba were isolated and characterised by spectroscopic methods. HPLC was used for the quantitative analyses of these iridoids and the chromatograms of bark and latex showed a similar iridoid composition. Both parts of the plant are used in folk medicine for the treatment of various ailments. KEY-WORDSApocynaceae, HPLC, Himatanthus sucuuba, iridoids, quantitative determination. Determinação quantitativa por CLAE de iridóides nas cascas e látex de Himatanthus sucuuba RESUMO Os iridóides principais das cascas e látex de Himatanthus sucuuba foram isolados e caracterizados por métodos espectroscópicos. CLAE foi utilizada para a análise quantitativa desses iridóides e os cromatogramas da casca e do látex apresentaram uma composição semelhante de iridóides. Ambas as partes da planta são utilizadas na medicina popular para o tratamento de várias doenças. PALAVRAS-CHAVEApocynaceae, CLAE, Himatanthus sucuuba, iridóides, determinação quantitativa.

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Ésteres triterpênicos de Himatanthus sucuuba (Spruce) Woodson

Cited by 32 publications

References 19 publications

Triterpenes and flavonoids from the roots of Mauritia flexuosa

Triterpenes and flavonoids from the roots of Mauritia flexuosa

Himatanthus lancifolius (Müll. Arg.) Woodson, Apocynaceae: estudo farmacobotânico de uma planta medicinal da Farmacopeia brasileira 1ª edição

Quantitative determination by HPLC of iridoids in the bark and latex of himatanthus sucuuba

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