Triterpenes and flavonoids from the roots of Mauritia flexuosa

Koolen, Héctor H. F.; Soares, Elzalina Ribeiro; Silva, Felipe M. A. da; Souza, Antônia Queiroz Lima de; Filho, Édson Rodrigues; Souza, Afonso Duarte Leão de

doi:10.1590/s0102-695x2011005000201

Cited by 29 publications

(20 citation statements)

References 21 publications

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“…Os resultados mostraram um padrão de fragmentação característico para as duas substâncias, com perda das unidades de açúcar (m/z 609/301 e m/z 463/301) e a fragmentação das respectivas agliconas gerando o íon 1,2 A -(m/z 301/179), ambas em concordância com a literatura [37][38][39][40][41][42][43] (Material suplementar).…”

Section: Detecção De Flavonoides Por Ccd Clae-dad E Ies-emunclassified

Perfil de flavonoides e avaliação do potencial antioxidante e citotóxico de Bauhinia purpurea (Fabaceae) da região amazônica

Santos¹,

Almeida²,

Lima³

et al. 2014

Quím. Nova

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FLAVONOID PROFILES AND EVALUATION OF ANTIOXIDANT POTENTIAL AND CYTOTOXICITY OF AMAZONIANBauhinia purpurea (Fabaceae). Plants of the Bauhinia species (Fabaceae) are used in the treatment of several infections and diseases, especially diabetes. In this paper, with an aim to contribute to the knowledge of the chemistry and therapeutic potential of the Amazonian species of the genus Bauhinia, flavonoid profiles in the leaves and branches of Bauhinia purpurea collected in Manaus and São Gabriel da Cachoeira/AM were analyzed by HPLC-DAD and ESIMS. Differences in the flavonoid profiles were detected along with the presence of rutin and isoquercitrin in the leaves collected in Manaus. All samples showed antioxidant activity, however, no cytotoxic activity against cell lines MDA-MB435 (breast), , and SF-295 (glioblastoma) could be detected.Keywords: Bauhinia purpurea; rutin; isoquercitrin. INTRODUÇÃOO gênero Bauhinia pertencente à família Fabaceae (subfamília: Cercideae) contém cerca de 300 espécies que são conhecidas popularmente no Brasil como pata-de-vaca pelo formato bilobado de suas folhas. 1 Elas são usadas na medicina tradicional em diversas partes do mundo por suas propriedades analgésica, antidiabética, antiinflamatória, antimicrobiana, adstrigente, diurética no tratamento de inchaços e tumores estomacais, diarréia e úlcera. 2-5 O uso popular mais comumente relatado para esse gênero no Brasil está relacionado à atividade hipoglicemiante, com várias espécies usadas para esse fim, em especial Bauhinia forficata, que é amplamente comercializada em variadas formas farmacêuticas. 6,7 As espécies de Bauhinia contêm diversas substâncias, como flavonoides livres e glicosilados, terpenoides, esteroides, ácidos fenólicos e alcaloides. 6-9 De espécimes asiáticos de B. purpurea foram isolados além de flavonoides, como kaempferol-3-galactosídio, isoquercitrina, rutina e astragalina, compostos raros da classe oxepinos, bauhiniastatinas, alguns com atividade citotóxica. [10][11][12] De um modo geral, as propriedades terapêuticas das espécies, especialmente as atividades antioxidante e hipoglicemiante, têm sido correlacionadas à presença de compostos fenólicos, em especial de flavonoides glicosilados, como a kaempferitrina, vinculada à ação hipoglicemiante da espécie B. forficata. [13][14][15] O estudo da espécie B. purpurea frente à atividade antioxidante vem ganhando destaque no estudo do gênero, já que seus extratos têm exibido potencial intermediário ou equivalente aos padrões geralmente utilizados nos testes para esta atividade. As substâncias fenólicas, atribuídas como as principais responsáveis por essas atividades, tem sido investigadas por meios cromatográficos e espectrométricos, na busca para estabelecer um perfil cromatográfico dentro da espécie. [16][17][18][19] Na região amazônica, o uso de espécies desse gênero não é diferente, havendo relatos para o tratamento de diabetes nos estados do Acre, Amazonas e Pará. As espécies são encontradas em muitas feiras e comércios a céu aberto, especialmente folhas, para uso co...

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Section: Detecção De Flavonoides Por Ccd Clae-dad E Ies-emunclassified

Perfil de flavonoides e avaliação do potencial antioxidante e citotóxico de Bauhinia purpurea (Fabaceae) da região amazônica

Santos¹,

Almeida²,

Lima³

et al. 2014

Quím. Nova

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“…This dioecious tropical palm has high ecological, cultural and economic value, however destructive harvesting practices to obtain the fruits undermine the palm's potential in rural and regional economies (Koolen, Soares, et al, 2013). Swamps which are dominated by M. flexuosa are popularly known as buritizais in Brazil, occurring throughout the Amazon region and making its resources accessible to the harvesters in large quantities (Koolen, Soares, da Silva, de Souza, Rodrigues-Filho, et al, 2012). The antioxidant properties of Amazonian fruits have been known for a long time and have been the subject of many scientific studies (Morales-Soto et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Simultaneous quantification of phenolic compounds in buriti fruit (Mauritia flexuosa L.f.) by ultra-high performance liquid chromatography coupled to tandem mass spectrometry

Bataglion

Silva

Eberlin

et al. 2014

Food Research International

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“…23 In the pulp there are phenolic compounds, flavonoids and phytosteroids. 24 And in the roots there are flavonoids and triterpenes 25,26 (Table 2). Aldehydes were not detected as well as reducing sugars in both TLC and Fehling reactions.…”

Section: Resultsmentioning

confidence: 99%

Comparative Studies Between Mauritia flexuosa and Mauritiella armata

Royo¹,

Rocha²,

Santos³

et al. 2019

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Mauritia flexuosa and Mauritiella armata belong to the family Arecaceae and are widely found in Brazil. Aim: In this work were evaluated: the phytochemical profile of the secretion popularly known as M. flexuosa wine, antioxidant activity of leaf, root and petiole hydroethanolic extracts of the two species, as well as the quantification of flavonoids and the chromatographic profile by means of High Performance Liquid Chromatography. Materials and Methods: The chromatographic profile was determined by high performance liquid chromatography, quantification of flavonoids and antioxidant activity, were performed by spectrophotometric method. Results: Antioxidant activity and presence of flavonoids were observed in the extracts of all the analyzed structures of the two species. The phytochemical profile of the wine evidenced the presence of secondary metabolites reported in other structures of M. flexuosa. In the chromatographic analysis, it was observed that the extracts evaluated have between three and nine compounds. Conclusion: Further studies should be performed to identify the active compounds in the two species. Key Messages: In this work were evaluated: the phytochemical profile of the secretion popularly known as M. flexuosa wine, antioxidant activity of leaf, root and petiole hydroethanolic extracts of the two species Mauritia flexuosa and Mauritiella armata (Arecaceae), as well as the quantification of flavonoids and the chromatographic profile. GRAPHICAL ABSTRACT SUMMARY• The current work were evaluated: the phytochemical profile of the M. flexuosa wine, antioxidant activity of leaf, root and petiole hydroethanolic extracts of the two species, as well as the quantification of flavonoids and the chromatographic profile by means of high performance liquid chromatography. • Researchers have been stated the presence of flavonoids and antioxidant activity of were observed in the extracts of all the analyzed structures of the two species. • Researchers have been stated the presence of phytoconstituents in wine. • In the chromatographic analysis, it was observed that the extracts evaluated have between three and nine compounds.

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Triterpenes and flavonoids from the roots of Mauritia flexuosa

Cited by 29 publications

References 21 publications

Perfil de flavonoides e avaliação do potencial antioxidante e citotóxico de Bauhinia purpurea (Fabaceae) da região amazônica

Perfil de flavonoides e avaliação do potencial antioxidante e citotóxico de Bauhinia purpurea (Fabaceae) da região amazônica

Simultaneous quantification of phenolic compounds in buriti fruit (Mauritia flexuosa L.f.) by ultra-high performance liquid chromatography coupled to tandem mass spectrometry

Comparative Studies Between Mauritia flexuosa and Mauritiella armata

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