Anti-inflammatory and anti-nociceptive effects of Zeyheria montana (Bignoniaceae) ethanol extract

Abstract

In this work, the analgesic and anti-inflammatory activities of

Effects of the serjania erecta and zeyheria montana ethanol extracts in experimental pulpitis in rats: A histological study

“…The presence of naphthoquinones and flavonoids in the Zeyheria montana extract (7) probably contributed to diminishing the pulp inflammatory reaction, particularly when compared with the control group, since these substances, especially the flavonoids, have the capacity to reduce the inflammatory reaction and inhibit lipid peroxidation, thus acting as antioxidant (13). Guenka et al (8) observed that ethanol extract of Zeyheria montana presents antinociceptive and anti-inflammatory activities, which could be important for the pharmacological control of pain and inflammation.…”

“…In this study, the concentrations of the extracts and the intraperitoneal administration were chose because of the good an-ti-inflammatory effects obtained by Guenka et al (8). However, for use in humans, extensive pharmacological and toxicological studies are necessary to test the safe, half-life and effectiveness of these phytotherapic agents, mainly when orally administered.…”

“…Saline physiological solution that was used for preparing the solutions of the extracts was administered via IP in equal volume in the animals of Groups I and II. The concentrations of the extracts and the intraperitoneal administration were chose because of the good anti-inflammatory effects previously obtained by Guenka et al (8). …”

“…This species produces terpenes and flavonoids (7). Guenka et al (8) observed important antinociceptive and anti-inflammatory activity of the ethanol extract of Zeyheria montana, administered intraperitoneally.…”

<i>In Vitro</i> Propagation and Conservation of <i>Zeyheriamontana</i> Mart: An Endangered Medicinal Plant

“…Its leaves produce ursolic, oleanolic and betulic acids, pentacyclictriterpenoids, with validated biological properties, such as anticancer activity [1], inhibitory effects on NO production and iNOS induction [2], anti-inflammatory [3], antifungal [4], diuretic [5]. Ethanol extract from Z. montana leaf possesses anti-nociceptive [6] and anti-inflammatory [7] activities and flavanones showed cytotoxicity against human NCI-ADR/RES and K562 cell lines [8].…”