Experimental infection of canine peritoneal macrophages with visceral and dermotropic Leishmania strains

Use of Phage Display technology in development of canine visceral leishmaniasis vaccine using synthetic peptide trapped in sphingomyelin/cholesterol liposomes

“…Control of CVL is proposed to be central for limiting the endemic transmission cycle of this zoonotic disease [ 5 , 6 ]. There are evidences that Leishmania -infected dogs never achieve parasitological cure, and the widespread use of the available anti- Leishmania drugs for human and canine treatment may contribute to parasite drug resistance [ 7 , 8 ].…”

DH82 Canine and RAW264.7 Murine Macrophage Cell Lines Display Distinct Activation Profiles Upon Interaction With Leishmania infantum and Leishmania amazonensis

“…***p < 0.0001. (Madeira et al, 1999). Although L. infantum is implicated in canine leishmaniasis, the detection of other species of Leishmania in naturally infected dogs has been reported (Sanches et al, 2016;Valdivia et al, 2017;Alves Souza et al, 2019).…”

In vitro infection by Leishmania infantum in the peripheral blood mononuclear cell-derived macrophages from crab-eating foxes ( Cerdocyon thous )

“…We will consider subsets of cells cultivated and the evaluation of cytokine production. Madeira et al (1999) cultivated macrophages derived from peritoneal exudates of dogs to study the virulence of L. infantum, Leishmania braziliensis and Leishmania amazonensis. They observed that L. infantum has a greater affinity for the canine cells.…”