Chronic carriers of hepatitis B surface antigen in an endemic area for schistosomiasis mansoni in Brazil

Serufo, José Carlos; Antunes, Carlos Maurício de Figueiredo; Pinto-Silva, Rogério Augusto; Gerspacher-Lara, Rogério; Rayes, Abdunnabi Ahmed Mustafa; Drummond, Sandra; Reis, Christian-Santiago; Martins, M. J.; Mingoti, Sueli Aparecida; Lambertucci, José Roberto

doi:10.1590/s0074-02761998000700046

Cited by 17 publications

(7 citation statements)

References 20 publications

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“…The prevalence in Northern, Central and Southern governorates was more or less similar. It is common to find a heterogeneous pattern of HBV endemicity inside the same country [19], [20]. Similar to the pattern known worldwide [4], [8], males were at higher risk of contracting HBV infection compared to females.…”

Section: Discussionmentioning

confidence: 68%

Prevalence and Risk Factors of Hepatitis B Virus Infection in Bahrain, 2000 through 2010

Janahi

2014

PLoS ONE

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Hepatitis B infection is one of the world's major infectious diseases with about 350 million chronic carriers. Because no data is published on the prevalence and risk factors of this important disease in Bahrain, this article evaluates the available data from 2000 to 2010 to estimate the prevalence of the infection and to evaluate the risk factors. Epidemiologic data on HBV cases were collected from the major hospitals and health centers in Bahrain and statistically analyzed. Over this indicated decade, 877,892 individuals were screened for HBV infection and 5055 positive cases were reported in Bahrain. The prevalence of HBV infection during that period was 0.58%. Although there was no significant difference in the prevalence over the period of 10 years, the actual number of positive cases has almost doubled in the later years especially in 2007 and 2008. The prevalence was significantly higher among males (62.3%; P<0.01). Most cases were associated with non Bahrainis and the prevalence was significantly higher among them (68.3%; P<0.01) than it was among Bahrainis (31.7%). Seventy eight percent (2877/3690) of non Bahraini cases were for citizens of six countries which are highly endemic for HBV, namely India, Pakistan, Bangladesh, Philippines, Indonesia and Ethiopia. Dental procedures and surgical operations were the main risk factors of infection as 37.2% and 35.6% of the patients were probably infected through this route. The prevalence of hepatitis B virus infection in Bahrain indicates that Bahrain had low HBV endemicity for the last 10 years (2000–2010). Our study verifies the significant role played by expatriates/immigrants in the present epidemiology of hepatitis B in Bahrain. Increasing HBV vaccination of high risk groups, active educational and media campaign, screening HBV infection during pregnancy, and surveillance of hepatitis B infected individuals will further decrease the prevalence of the disease in Bahrain.

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Section: Discussionmentioning

confidence: 68%

Prevalence and Risk Factors of Hepatitis B Virus Infection in Bahrain, 2000 through 2010

Janahi

2014

PLoS ONE

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“…Hyams et al (1987) concluded that there was no correlation between S. mansoni infection, with or without hepatosplenomegaly and HBsAg positivity. The study of Serufo et al (1997) in endemic area from Minas Gerais also did not show association between schistosomiasis and HBV. In Brazil, Guimarães (1975) recorded 4.4% of patients infected with hepatitis B virus among patients with hepatosplenic schistosomiasis (as compared to 1.5% in the hepatointestinal form and 0.6% in controls); Lyra (1976) found 7.8% of HBV markers in the hepatosplenic form of schistosomiasis (as compared to 1.5% in the hepatointestinal form and 1.3% in controls).…”

Section: Discussionmentioning

confidence: 72%

Prognosis of schistosomiasis mansoni patients infected with hepatitis B virus

Conceição

Argento

Chagas

et al. 1998

Mem. Inst. Oswaldo Cruz

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“…The results were not uniform, some of them showing association between B virus and schistosomiasis 2,19,20,37,52,61 , while others did not demonstrated a higher prevalence 27,28,40,73 or a higher rate of chronification of hepatitis 69 .…”

Section: Introductionmentioning

confidence: 87%

Hepatitis B and C virus markers among patients with hepatosplenic mansonic schistosomiasis

Aquino¹,

Chieffi

Catunda³

et al. 2000

Rev. Inst. Med. trop. S. Paulo

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SUMMARYPurpose: To evaluate the frequency and the consequences of the co-infection of hepatitis B and C viruses in patients with hepatosplenic schistosomiasis (HSS).Methods: B and C serologic markers, exposure to risk factors, biochemical assays, upper gastrointestinal endoscopies, and abdominal ultrasonograms were evaluated in 101 patients with HSS from 1994 to 1997. Whenever possible, PCR was tested and histopathological studies were reviewed.Results: At least one HBV virus marker was found in 15.8%, and anti-HCV was detected in 12.9% of the subjects. The seropositive subjects tended to be older than the seronegative ones. A history of blood transfusion was significantly related to the presence of anti-HCV. Three (18.75%) out of 16 subjects exposed to B virus were HBsAg positive. Eleven (84.6%) out of thirteen patients who were anti-HCV positive demonstrated viral activity. Patients with ongoing viral infection presented a higher average level of liver aminotransferases, a higher frequency of cell decompensation and a higher rate of chronic hepatitis. Portal hypertension parameters were not influenced by viral exposure. Conclusions:The rate of hepatitis B and C viruses serologic markers observed in the patients with HSS was higher than the control group. The co-infection was responsible for a higher frequency of cell decompensation.

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Chronic carriers of hepatitis B surface antigen in an endemic area for schistosomiasis mansoni in Brazil

Abstract: Data on the association of schistosomiasis and hepatitis B in field-

Cited by 17 publications

References 20 publications

Prevalence and Risk Factors of Hepatitis B Virus Infection in Bahrain, 2000 through 2010

Prevalence and Risk Factors of Hepatitis B Virus Infection in Bahrain, 2000 through 2010

Prognosis of schistosomiasis mansoni patients infected with hepatitis B virus

Hepatitis B and C virus markers among patients with hepatosplenic mansonic schistosomiasis

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