Early sporogonic development in local vectors of Plasmodium falciparum in rural Cameroon

Abstract

In ongoing studies on experimental transmission of Plasmodium falciparum in the city of Yaounde gametocyte carriers are daily being identified among dispensary patients with malaria-like complaints. This species comprises 93% of all parasitemias and because of the selection criteria most patients have it as a recent infection. 17% of all P. falciparum-positives carry detectable gametocytes with little difference between youngsters and adults. Blood of adult carriers is taken and infection of Anopheles gambiae mosquitoes is attempted by membrane feeding; the establishment of infection is judged by the presence of oocysts.

A review of malaria transmission dynamics in forest ecosystems

“…pseudopunctipennis and fluctuating environmental conditions prevail and are compensated by the short extrinsic incubation period of P. vivax , long intrinsic incubation periods in the human liver [118], and by forest cover that increases the life expectancy of the vector [109]. Plasmodium species have evolved to fit local vectors, as observed in P. falciparum in rural Cameroon by shortening sporogony [119] as survival of the vector influences Plasmodium distribution [120]. An increase in vectorial capacity of An.…”