Doença de Chagas

Epidemiology, control and surveillance of Chagas disease: 100 years after its discovery

“…The other 47 species are wild and maintain a natural cycle only with wild mammals. T. infestans, which is the only strictly domesticated species, has been eliminated in Brazil, Chile and Uruguay, and its eradication or control in other South American countries is in progress (Lent & Wigodzinsky 1979, Forattini 1980, Dias & Coura 1997, WHO 2002, Dias & Macedo 2005, Coura 2008). …”

“…Other animals, such as pigs and caprines, have also been found to be infected. Birds, reptiles and fish do not become infected because they have "lysines" that destroy T. cruzi (Barretto 1964, Deane 1964, Dias & Macedo 2005, Coura 2008). …”

The evolution of Chagas disease (American Trypanosomiasis) control after 90 years since Carlos Chagas discovery

“…This method has been very widely used for many years, and the blue colouration imparted to the transfused blood generally disappears a few days after transfusion. In areas with lower seroprevalence of T. cruzi infection the recommended approach is to screen all potential blood donors using at least two serologi- cal tests (usually Indirect Haemaglutination and Indirect Fluorescent Antibody tests); at the same time the blood can also be screened for HIV, hepatitis and syphilis (Dias 1978, Schmunis 1991, WHO 1991. The third approach, used in non-endemic areas such as the USA, is based on a preliminary questionnaire to see if the donor has any history of possible contact with T. cruzi or infected Triatominae (eg.…”

Evolução clínica a longo prazo, correlacionando a presença de bloqueios da condução intraventricular em pacientes chagásicos e não chagásicos assintomáticos

“…O bloqueio completo do ramo direito (BCRD) é um achado freqüente 11 17 31 34 , sendo considerado alteração peculiar da cardiopatia chagásica quando associado ao desvio do ÂQRS para a esquerda 15 33 . O BCRD pode ser observado em 13 a 55% dos indivíduos soropositivos 11 31 33 34 , prevalência esta que varia segundo a população estudada. No caso do bloqueio completo do ramo esquerdo (BCRE), esses estudos apontaram que sua prevalência é menor, situando-se entre 2 a 5 %.…”