Epidemiological aspects of adherence to the treatment of hypertension

Andrade, Jadelson Pinheiro de; Vilas-Boas, Fábio; Chagas, Hildenizia; Andrade, Marianna

doi:10.1590/s0066-782x2002001300005

Cited by 26 publications

(21 citation statements)

References 11 publications

(9 reference statements)

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“…Medications play an important therapeutic role in hypertension care, both for their low cost in the early stages of the disease and for adherence to treatment, which, up to now, has been higher than adherence to lifestyle changes 12 . The global scenario of NCD led the World Health Organization to launch, in 2012, the challenge to reduce mortality from these diseases by 25.0% by 2052 2 . The WHO considered access to medicines an essential component in achieving this goal 2 , 6 .…”

Section: Introductionmentioning

confidence: 99%

Access to and use of high blood pressure medications in Brazil

et al. 2016

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OBJECTIVE To analyze the access to and use of medicines for high blood pressure among the Brazilian population according to social and demographic conditions.METHODS Analysis of data from Pesquisa Nacional Sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos (PNAUM – National Survey on Access, Use and Promotion of Rational Use of Medicines), a nationwide cross-sectional, population-based study, with probability sampling, carried out between September 2013 and February 2014 in urban households in the five Brazilian regions. The study evaluated the access and use of medicines to treat people with high blood pressure. The independent variables were gender, age, socioeconomic status and Brazilian region. The study also described the most commonly used drugs and the percentage of people treated with one, two, three or more drugs. Point estimations and confidence intervals were calculated considering the sample weights and sample complex plan.RESULTS Prevalence of high blood pressure was 23.7% (95%CI 22.8–24.6). Regarding people with this condition, 93.8% (95%CI 92.8–94.8) had indication for drug therapy and, of those, 94.6% (95%CI 93.5–95.5) were using the medication at the time of interview. Full access to medicines was 97.9% (95%CI 97.3–98.4); partial access, 1.9% (95%CI 1.4–2.4); and no access, 0.2% (95%CI 0.1–0.4). The medication used to treat high blood pressure, 56.0% (95%CI 52.6–59.2) were obtained from SUS (Brazilian Unified Health System), 16.0% (95%CI 14.3–17.9) from Popular Pharmacy Program, 25.7% (95%CI 23.4–28.2) were paid for by the patients themselves and 2.3% (95%CI 1.8–2.9) were obtained from other locations. The five most commonly used drugs were, in descending order, hydrochlorothiazide, losartan, captopril, enalapril and atenolol. Of the total number of patients on treatment, 36.1% (95%CI 34.1–37.1) were using two medicines and 13.5% (95%CI 12.3–14.9) used three or more.CONCLUSIONS Access to medicines for the treatment of high blood pressure may be considered high and many of them are available free of charge. The most commonly used drugs are among those recommended as first-line treatment for high blood pressure control. The percentage of people using more than one drug seems to follow the behavior observed in other countries.

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Section: Introductionmentioning

confidence: 99%

Access to and use of high blood pressure medications in Brazil

et al. 2016

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“…The reasons for drug nonadherence may be due to normalization of blood pressure, side effects of the medications, forgetting to use the medication, cost of medication, fear of mixing alcohol and medication, ignoring the need for continuing the treatment, use of an alternative treatment, fear of intoxication, fear of hypotension, and fear of mixing the medication with other drugs (Andrade, Vilas-Boas, Chagas, & Andrade, 2002).…”

Section: Discussionmentioning

confidence: 99%

Predicting risk factors of working aged hemorrhagic stroke patients in a tertiary teaching hospital in Chiang Mai

Triamvisit¹,

Chongruksut²,

Watcharasaksilp³

et al. 2018

Asian/Pacific Island Nursing Journal

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Stroke is the third leading cause of morbidity and mortality in Thailand accounting for a significant and increasing share of hospital costs. The purpose of this project is to study the epidemiology of the prevalence and its predicting factors of working aged hemorrhagic stroke (HS) patients admitted at a tertiary teaching hospital in Chiang Mai, Thailand.We conducted a five-year retrospective descriptive study. The subjects in this study were patients diagnosed with HS, between 15-59 years of age, and admitted to a tertiary teaching hospital in Chiang Mai, Thailand from January 2009 to December 2013. A total of 404 working aged adults who had HS were admitted to the hospital during this review period; 60.9% males and 39.1% females. Nearly 70% of patients were between 46-59 years of age (M = 47.5, SD = 9.8). Of the patients admitted to the hospital, 76.7% were transferred there from other hospitals. Intracerebral hemorrhage was present in 59.7% of patients. Severe HS occurred in 35.9% of the patients with a Glasgow Coma Score from 3-8. Approximately 69% of the working aged HS patients required surgery. The top five identified risk factors for HS were hypertension (83.4%), hyperlipidemia (38.9%), alcohol consumption (21.5%), smoking (15.3 %), and drug non-adherence (14.9%).We found significantly associated risk factors in working-aged HS by multivariate analysis among male gender (p < .001), drug non-adherence (p = .047), and hypertension (p = .048). Raising awareness to reduce risk behavior and health promotion in the community are the keynotes for health care providers in working-aged HS prevention.

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“…Identifying factors that determines non-compliance of hypertensive patients to treatment is, therefore, of vital importance in applying therapeutic strategy and in obtaining satisfactory results [28,29].…”

Section: Discussionmentioning

confidence: 99%