Urinary tract infection in full-term newborn infants: value of urine culture by bag specimen collection

Abstract

SUMMARY: Objective: to evaluate the efficacy of urine culture by bag specimen for the detection of neonatal urinary tract infection in full-term newborn infants. Retrospective study (1997) including full-term newborn infants having a positive urine culture (>100,000 CFU/ml) by bag specimen collection. The urinary tract infection diagnosis was confirmed by positive urine culture (suprapubic bladder aspiration method). The select cases were divided into three groups, according to newborn infant age at the bag specimen collection: GI (< 48 h, n = 17), GII (48 h to 7 d, n = 35) and GIII (> 7 d, n = 9). Sixty one full-term newborn infants were studied (5.1 % of total infants). The diagnosis was confirmed on 19/61 (31.1 %) of full-term infants born alive. Distribution among the groups was: GI = 2/17 (11.8 %), GII = 10//35 (28.6 %), and GIII = 7/9 (77.7 %). The most relevant clinical symptoms were: fever (GI -100 %, GII -91.4 %) and weight loss (GI -35.3 %, GII -45.7 %). Urine culture results for specimens collected by suprapubic aspiration were: E. coli GI (100 %), GII (40 %) and GIII (28.6 %), E. faecalis GI (30%), Staphylococcus coagulase-negative GII (20 %) and GIII (42.8 %), and Staphylococcus aureus GII (10 %). Correlation between positive urine culture collection (bag specimen method) and urinary tract infection diagnosis, using relative risk analysis, produced the following results: GI=0.30 (CI95% 0.08-1.15), GII=0.51 (CI 95% 0.25-1.06) and GIII=3.31 (CI95% 1.8-6.06) The most frequent urinary tract infection clinical signs in the first week were fever and weight loss, while non-specific symptomatology occurred later. E. coli was most frequent infectious agent, although from the 7th day of life, staphylococcus was noted. The urine culture (bag specimen method) was effective in detecting urinary tract infection only after the 7th day of life. DESCRIPTORS: Urine culture. Urinary tract infection. Newborn infant.

Epidemiology of urinary tract infection in neonatal intensive care unit: A single center study in Egypt

“…[8] UTI may have long-term consequences as they may produce kidney damage, which may lead later in life to hypertension, recurrent infections, and renal failure. [9] In our study we found incidence of proven UTI in NICU was 15.05% (33/206) and prevalence among clinically suspected cases of UTI in NICU was 41.3% (33/75), this matches what Jurczak, and his colleagues, [10] found in 2007, that the UTI represents 14.9% in NU and NICU. But lower percentage than our result was recorded by Garcia and his group, [11] in 2002, where they found the incidence of UTI of 160 participants enrolled was 7.5%.…”

“…In our study 79.5% of cases with neonates admitted because of sepsis have proven UTI (31/39). Our study coincides with that of Falcão et al [9] in 2000, which showed that the presence of infection was one of the most prevalent associated risk factors (63.2%), therefore, UTI should be considered in all infants who have signs of sepsis. A lower percentage of UTI associated with septicemia was recorded by Movahedian et al [13] where UTI associated with septicemia was observed in 10.5%.…”

“…In our study, premature rupture of membranes is present in 5 cases out of 31 with UTI, that is, 35.7% of our findings coincided with that of Falcão's, [9] in 2000, who showed that there was premature rupture of membranes in 26.3% of cases with UTI, but in contrast to our result a study done by Garcia, [11] in 2002, found that the premature rupture of membranes was 0 in cases with UTI. This difference can be explained by their selection of only afebrile jaundiced neonates.…”

The causative microorganisms and the underlying urological anomalies in children with urinary tract infection

“…11,16,17 However, many published studies have reported Klebsiella as the commonest organism isolated in urine cultures and very low incidence of Ecoli causing UTI. [18][19][20][21] This difference could be because of difference in demography and sampling techniques in different studies. In present study the associated urological anomalies were detected in 42.24% cases of symptomatic UTI.…”

Clinical and laboratory profiles of urinary tract infection among children at Prof. Dr. R. D. Kandou Hospital Manado

“…4 UTI is a common cause for a significant number of outpatient visits. 3,5,6 Recurrence is common and occurs in approximately 18% of male infants and 26% of female infants. 7 Fever remains a more common presentation in the neonates, infants, and younger children whereas older children present with other symptoms.…”