2004
DOI: 10.1590/s0037-86822004000300011
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Abstract: In order to verify the viability of platelet concentrate during its preservation period when added with two trypanosomicidal chemical substances, gentian violet and quinoline WR6026, we tested these concentrates and verified the following parameters: number of platelets, pH and platelet aggregation test with a pair of agonists. Significant alterations were observed in the platelet concentrate treated with gentian violet suggesting important damage to the platelet viability. With WR6026 similar values to the co… Show more

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Cited by 6 publications
(2 citation statements)
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“…GV presence in blood decreases its quality slightly yet it is not significant enough to cause any clinical symptoms (48). This efficiency together with the low price of GV makes it an extremely economical prophylactic element (48,49). In studies by R.C.…”
Section: Anti-parasitic Effectmentioning
confidence: 99%
“…GV presence in blood decreases its quality slightly yet it is not significant enough to cause any clinical symptoms (48). This efficiency together with the low price of GV makes it an extremely economical prophylactic element (48,49). In studies by R.C.…”
Section: Anti-parasitic Effectmentioning
confidence: 99%
“…A violeta genciana tem sido usada com a finalidade quimioprofilática, mas, embora seja eficaz na eliminação dos parasitas, restrições impedem que seja administrada. Essas restrições são prejudiciais ao organismo, pois interferem na preservação plaquetária, induzindo lise ou formação de grumos (FERREIRA et al, 2010a;SOARES et al, 2004).…”
Section: Desenvolvimento De Novas Terapiasunclassified