Rastreamento sorológico para hepatite B em profissionais de saúde na cidade de Goiânia - Goiás

Abstract

Markers for hepatitis B virus in health care workers were analysed in 625 employees of three institutions in Goiânia city. The virus prevalence was 23.4% related to different markers (AgHBs, anit-HBs and anti-HBc). Among the positive individuals, 1.3% presented acute infection, 1.0% were virus carriers and 21.1% presented only anti-HBs and 32.6% only anti-HBc as markers. There were 19 reports of virus vaccination. Eight of them seroconverted for anti-HBs and 6 were positive for both anti-HBc and anti-HBs. Higher prevalence rates were found above 30 year of age (p < 0.05). The male and female prevalence rates were 29.5% and 21.1% (p < 0.05) respectively. The virus prevalence rates among blood and patient contacts were 25.9% (p < 0.05) and the highest prevalence was found in persons followed up for at least ten years (p < 0.05). The greatest risk section has shown to be hemodialysis unit personnel with a percentual of 77% (p < 0.05).

Serological markers and risk factors related to hepatitis B virus in dentists in the Central West region of Brazil

“…In addition, HCW studies usually show that the number of years in the profession can be a risk factor (1,10,13,15,20), * p value from χ 2 test; ** Needlestick exposure -ever had in dental practice; *** Oral Surgery Specialties -periodontics, endodontics and implantology were included in it; ****NO or Inc -No vaccination or incomplete schedule (less then three doses); *****NR -not realized (more than two exposure variables); ****** PPE -Personal protective equipment (masks, gloves, protective eyewear, protective clothing and hair protection) including dentists (3,7,16,17) as observed in the present study.…”

“…Considering an expected HBV infection rate for HCWs in region of 23.5% (1,20) it was estimated that 673 dentists would be representative, with 3% margin of error, 95% of confidence level and a 10% safety margin.…”

“…The occupational risk for HBV acquisition varies according to the work place in the health care setting and the HCW's time of exposure to the agent (1,6,10).…”

Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiânia, Goiás: detection of viral DNA and determination of subtypes

“…From the subtyped samples, 32 (62.7%) were adw 2 , 12 (23.5%) ayw 3 and the remaining samples were ayw 2 (9.8%) and adw 4 (3.9%). The analysis in relation to the year shows that the subtype adw 2 occurred throughout the years of study, while the subtypes ayw 3 and adw 4 occurred only during the year of 1996 and the ayw 2 in 1995 and in 1996 (Table 3).…”

“…In Goiânia-Goiás, studies about HBV seroprevalence have been developed and the important spreading of the agent in this region has been demonstrated 3,4,6,7,32,39 . However, there is no data regarding this virus in population that presents clinical suspect of hepatitis.…”