Hepatitis C virus infection in hemodialysis patients and workers. A case-control study in Santa Catarina State dialysis units

Moraes, C. R.

doi:10.1590/s0036-46652001000200015

Cited by 3 publications

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“…In our country, HCV prevalence rates of 20.3%, 23.8%, 33.4% and 39% were recently found in Santa Catarina (Moraes 2001), Bahia (Santana et al 2001), Minas Gerais (Busek et al 2002), and Goiás (Carneiro et al 2001), respectively.…”

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confidence: 61%

[No Title Available]

Souza

Luz²,

Teles

et al. 2003

Mem. Inst. Oswaldo Cruz

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confidence: 61%

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Souza

Luz²,

Teles

et al. 2003

Mem. Inst. Oswaldo Cruz

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“…Noteworthy, however, is the high prevalence of genotype 2b among the patients treated in the hemodialysis units enrolled here, especially from one of the units studied. This is a unique characteristic, considering the low prevalence of this genotype in Brazil [15,21,33,39,40]. These findings suggest a potential role of nosocomial transmission among the patients involved.…”

Section: Discussionmentioning

confidence: 89%

Evidence of association between hepatitis C virus genotype 2b and nosocomial transmissions in hemodialysis centers from southern Brazil

Silva

Germano

Mendoza-Sassi

et al. 2013

Virol J

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BackgroundHepatitis C virus infection is a serious public health problem. Hemodialysis is considered one of the main risk factors of HCV infection, due to several invasive medical procedures and potential nosocomial transmission that patients with chronic renal failure (CRF) are continuously submitted. The aims of this study were to determine the prevalence of HCV and its genotypes in patients with CRF in hemodialysis units in southern Brazil.MethodsDemographic data and risk factors for HCV transmission were collected and analyzed. These data were obtained from patients undergoing hemodialysis treatment from January 2009 to August 2010, on two dialysis units of Rio Grande, southern Brazil. Genotyping was carried out by sequencing analysis of HCV NS5b, core-E1 junction and 5′UTR genomic regions.ResultsOne hundred fifty-nine patients under regular hemodialysis treatment were studied. HCV prevalence was 23.3%. HCV-infected patients had been on dialysis treatment for 91.9 months, a more prolonged period compared to HCV-negative patients (p = 0.001). While HCV genotypes 1b and 3a were identified as the most frequent strains, a surprisingly high proportion of genotype 2b was observed among patients in one of the dialysis centers compared to the general HCV-infected population of the same area. Hemodialysis treatment exposure time and healthcare working were associated with HCV infection.ConclusionsBesides the efforts to minimize nosocomial transmission of HCV, some events of transmission are still evidenced in dialysis units.

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Hepatitis C risk factor for patients submitted to dialysis

Baldessar¹,

Bettiol²,

Foppa³

et al. 2007

Braz J Infect Dis

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This article reports the results of the research which has evaluated the prevalence and factors associated to the presence of Hepatitis C in patients submitted to dialysis at the Clinica de Doenças Renais (Clinic of Renal Diseases) in Tubarao city (CRDT), Santa Catarina State, Brazil, in the period between January 1 st , 2004 to December 31 st in the same year. The prevalence of 16.8% of Hepatitis C in the studied population and the time-length of dialysis as significative risk factor have become evident. The non-correlation of seropositivity of the followings factors is also indicated: age, gender, base diseases, infrastructures, the type of clinic machines, the type of dialyser, used membranes, the machine sterilisation and substances for this process as well as the number of times of the dialyser reutilization. The data represented in this project suggest that the Hepatitis C presents high prevalence in patients in dialysis and the time-length of the treatment is a risky factor to acquire the infection.

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Hepatitis C virus infection in hemodialysis patients and workers. A case-control study in Santa Catarina State dialysis units

Abstract: de-Estudo epidemiológico caso-controle da infecção pelo vírus da hepatite C em pacientes e funcionários das unidades de hemodiálise do Estado de Santa Catarina. São Paulo, 1998.

Cited by 3 publications

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Evidence of association between hepatitis C virus genotype 2b and nosocomial transmissions in hemodialysis centers from southern Brazil

Hepatitis C risk factor for patients submitted to dialysis

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