[No Title Available]

Souza, Karla Prado de; Luz, Jônio Arruda; Teles, Sheila Araújo; Carneiro, Megmar Aparecida dos Santos; Oliveira, Luciana Alves de; Gomes, Adriane S.; Dias, Miguel Joaquim; Gomes, Saint Clair; Yoshida, Clara Fumiko Tachibana; Martins, Regina Maria Bringel

doi:10.1590/s0074-02762003000500003

Cited by 29 publications

(2 citation statements)

References 37 publications

(51 reference statements)

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“…This is lower than studies conducted by Rawat 3,7,[9][10][11] Worldwide prevalence rate ranging from 4-15% for HBsAg in HD patients has been reported, whereas, in India it ranges from 3.4% to 45%. 4,12 We report 14.8% HBV positivity among HD patients which in agreement with the study conducted by Mittal et al (10.2%), Bhaumika et al (12.1%). 7,13 However, Rawat et al reported 7% HBV positivity and Saravanan et al reported 33.5% positivity in their studies.…”

Section: Discussionsupporting

confidence: 92%

Prevalence of asymptomatic hepatitis B virus and hepatitis C virus infections in patients with maintenance hemodialysis of a tertiary care hospital in western Maharashtra

Patil¹,

Munjappa²,

Gadgil³

et al. 2020

IJMR

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Introduction: Patients on Maintenance Hemodialysis (HD) are at high risk of viral hepatitis due to blood transfusion, prolonged vascular access, exposure to infected patients and contaminated equipments etc. Knowledge of the prevalence of such infections is very important to access magnitude of the problem because these infections play important role in the morbidity and mortality of hemodialysis (HD) patients. Aim and Objectives: This study was done to determine the prevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections in patients on hemodialysis at our tertiary care hospital of Western Maharashtra. Materials and Methods: Settings and Design: Hospital based cross sectional study was conducted for six months in HD unit at our tertiary care hospital. All patients (n=135) were screened for Hepatitis B surface antigen and antibodies to HCV (anti-HCV). Prevalence, age and sex wise distribution as well as risk factors for transmission of these infections were observed. Results: Total 135 HD patients were screened for presence of HBV and HCV infections. Of these, 39 (28.9%), 20 (14.8%), 6 (4.4%) were found to be having HCV, HBV and Dual HBV and HCV infection respectively. Conclusions: HCV was the most prevalent among HD patients than HBV. History of multiple blood transfusions, HD outside center or longer duration of HD were all important risk factor noted for high prevalence of sero-positivity for HBV and/or HCV. Strict adherence to universal precautions careful attention to hygiene and strict sterilization of dialysis machines are important to prevent further transmission of these viruses.

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Section: Discussionsupporting

confidence: 92%

Prevalence of asymptomatic hepatitis B virus and hepatitis C virus infections in patients with maintenance hemodialysis of a tertiary care hospital in western Maharashtra

Patil¹,

Munjappa²,

Gadgil³

et al. 2020

IJMR

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show abstract

“…The prevalence of HCV infection in patients undergoing dialysis is persistently greater than that in the general population being endemic in haemodialysis (HD) units around the world, predominantly in Mediterranean and developing countries of the Middle and Far East. Nosocomial transmission of HCV infection has been reported to be a considerable route in modern hospital dialysis units, particularly during the outbreaks of infection [1][2][3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Risk Factors of HCV Infection among Haemodialysis Patients at Dialysis Centers in Khartoum State - Sudan

Abdalla¹,

Shaaban²,

Elkhidir³

2017

IOSR JDMS

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Hepatitis C virus share razors. P values = (0.0001, 0.0031, 0.0001, 0.0018, 0.0005 and 0.0002) Results: Field workers interviewed ten dialysis centers with a total of 287 study subjects. Sixty out of 287 (20.9%) was found to be anti-HC reactive. The multivariate analysis indicated as risk factors associated to anti-HCV positivity the number of blood transfusion received, duration of dialysis treatment, number of units of treatment, history of surgeries, multiple injections and using

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Hepatitis C virus screening and clinical monitoring of biomarkers in patients undergoing hemodialysis

Maia

Martins‐Filho

Teixeira-Carvalho

et al. 2009

Journal of Medical Virology

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In this study, 395 volunteers were enrolled to investigate the seroprevalence of hepatitis C virus, the immunological and the alanine aminotransferase (ALT) biomarkers amongst hemodialysis patients, living in Manaus, Brazil. An overall seroprevalence of 13.9% was found in the hemodialysis patients. Analysis of seroconversion patterns demonstrated that most patients with HCV seroconverted up to 10 years following the first hemodialysis session. Anti-NS5 antibody was detectable in 60.4% of patients with HCV. A lower percentage of circulating CD3(+) and CD4(+) T-cells was found in patients seronegative for HCV, whereas a higher frequency of CD8(+) T-cells was the hallmark of patients with HCV. An overall low activation state of monocytes and eosinophils were observed in hemodialysis patients. In contrast, a higher frequency of activated neutrophils was observed in patients with HCV, selectively in the NS5+ subgroup. All hemodialysis patients had a higher percentage of activated lymphocytes, with the higher activation state in patients with NS5- reactivity. Higher ALT levels were observed in patients with HCV, especially in the NS5+ subgroup. Interestingly, the ALT levels were correlated negatively with the lymphocyte activation state, selectively in the NS5- subgroup, suggesting a protective role of these activated lymphocytes in patients with HCV. These findings reinforce the importance of the transmission of HCV among hemodialysis patients, suggesting that apart from the HCV screening, the serological and ALT biomarkers may represent important predictors of morbidity and/or mortality among patients undergoing hemodialysis.

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[No Title Available]

Abstract: A survey was conducted in the hemodialysis population of the state of Tocantins, Brazil, aiming

Cited by 29 publications

References 37 publications

Prevalence of asymptomatic hepatitis B virus and hepatitis C virus infections in patients with maintenance hemodialysis of a tertiary care hospital in western Maharashtra

Prevalence of asymptomatic hepatitis B virus and hepatitis C virus infections in patients with maintenance hemodialysis of a tertiary care hospital in western Maharashtra

Prevalence and Risk Factors of HCV Infection among Haemodialysis Patients at Dialysis Centers in Khartoum State - Sudan

Hepatitis C virus screening and clinical monitoring of biomarkers in patients undergoing hemodialysis

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