[No Title Available]

Souza, Karla Prado de; Luz, Jônio Arruda; Teles, Sheila Araújo; Carneiro, Megmar Aparecida dos Santos; Oliveira, Luciana Alves de; Gomes, Adriane S.; Dias, Miguel Joaquim; Gomes, Saint Clair; Yoshida, Clara Fumiko Tachibana; Martins, Regina Maria Bringel

doi:10.1590/s0074-02762003000500003

Cited by 30 publications

(3 citation statements)

References 37 publications

(51 reference statements)

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“…This is lower than studies conducted by Rawat 3,7,[9][10][11] Worldwide prevalence rate ranging from 4-15% for HBsAg in HD patients has been reported, whereas, in India it ranges from 3.4% to 45%. 4,12 We report 14.8% HBV positivity among HD patients which in agreement with the study conducted by Mittal et al (10.2%), Bhaumika et al (12.1%). 7,13 However, Rawat et al reported 7% HBV positivity and Saravanan et al reported 33.5% positivity in their studies.…”

Section: Discussionsupporting

confidence: 92%

Prevalence of asymptomatic hepatitis B virus and hepatitis C virus infections in patients with maintenance hemodialysis of a tertiary care hospital in western Maharashtra

Patil¹,

Munjappa²,

Gadgil³

et al. 2020

IJMR

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Introduction: Patients on Maintenance Hemodialysis (HD) are at high risk of viral hepatitis due to blood transfusion, prolonged vascular access, exposure to infected patients and contaminated equipments etc. Knowledge of the prevalence of such infections is very important to access magnitude of the problem because these infections play important role in the morbidity and mortality of hemodialysis (HD) patients. Aim and Objectives: This study was done to determine the prevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections in patients on hemodialysis at our tertiary care hospital of Western Maharashtra. Materials and Methods: Settings and Design: Hospital based cross sectional study was conducted for six months in HD unit at our tertiary care hospital. All patients (n=135) were screened for Hepatitis B surface antigen and antibodies to HCV (anti-HCV). Prevalence, age and sex wise distribution as well as risk factors for transmission of these infections were observed. Results: Total 135 HD patients were screened for presence of HBV and HCV infections. Of these, 39 (28.9%), 20 (14.8%), 6 (4.4%) were found to be having HCV, HBV and Dual HBV and HCV infection respectively. Conclusions: HCV was the most prevalent among HD patients than HBV. History of multiple blood transfusions, HD outside center or longer duration of HD were all important risk factor noted for high prevalence of sero-positivity for HBV and/or HCV. Strict adherence to universal precautions careful attention to hygiene and strict sterilization of dialysis machines are important to prevent further transmission of these viruses.

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Section: Discussionsupporting

confidence: 92%

Prevalence of asymptomatic hepatitis B virus and hepatitis C virus infections in patients with maintenance hemodialysis of a tertiary care hospital in western Maharashtra

Patil¹,

Munjappa²,

Gadgil³

et al. 2020

IJMR

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“…The prevalence of HCV infection in patients undergoing dialysis is persistently greater than that in the general population being endemic in haemodialysis (HD) units around the world, predominantly in Mediterranean and developing countries of the Middle and Far East. Nosocomial transmission of HCV infection has been reported to be a considerable route in modern hospital dialysis units, particularly during the outbreaks of infection [1][2][3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Risk Factors of HCV Infection among Haemodialysis Patients at Dialysis Centers in Khartoum State - Sudan

Abdalla¹,

Shaaban²,

Elkhidir³

2017

IOSR JDMS

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Hepatitis C virus share razors. P values = (0.0001, 0.0031, 0.0001, 0.0018, 0.0005 and 0.0002) Results: Field workers interviewed ten dialysis centers with a total of 287 study subjects. Sixty out of 287 (20.9%) was found to be anti-HC reactive. The multivariate analysis indicated as risk factors associated to anti-HCV positivity the number of blood transfusion received, duration of dialysis treatment, number of units of treatment, history of surgeries, multiple injections and using

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“…Nosocomial transmission of HCV and HBV is an important contributing factor to the spread of these viruses [97,98]. Despite various infection control procedures in HD patients' prevalence and incidence rates of HBV and HCV are still significant [99,100]. Studies have shown that strict aseptic measures can virtually eliminate HCV contamination, even in units with a high prevalence of HCV infection [101].…”

Section: Discussionmentioning

confidence: 99%

Hepatitis C Infection in Hemodialysis Patients, Makkah, Saudi Arabia

Ghanim Hamid Al-Khattabi

2024

ARASET

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Hepatitis C virus (HCV) infection is the most common cause of chronic liver disease in the world and evaluation of the epidemiology of HCV infection was made possible by the development of a serological assay to detect antibodies to epitopes of HCV. Hemodialysis (HD) is considered to be one of the main risk factors of HCV transmission. The prevalence of antibodies to HCV (anti-HCV) in patients undergoing maintenance dialysis therapy (MDT) was found to be one of the highest among different risk groups and there is wide variation in the prevalence of HCV infection among different dialysis units and countries. Therefore, the prevalence of anti-HCV was studied in patients undergoing MDT. The current study is a cross section one, where a sample of 361 HD patients were selected randomly from HD centres in three governmental hospitals in Makkah city and they were subjected to assessment for the prevalence of anti-HCV by using questionnaires in addition to clinical measurements. The overall prevalence of anti-HCV among HD patients was 49.9% according to clinical measurements and questionnaires. The overall prevalence of anti-HCV among HD patients in Makkah city (49.9%) was comparable to that reported from other parts of the Kingdom of Saudi Arabia (KSA) and it is almost similar to the already reported positivity rate of (43.2%) from the eastern region of KSA and southern regions of KSA (45.5%). However, Strict adherence to universal precautions as recommended by the Centre for Diseases Control (CDC), meticulous regular disinfection of HD machines, Strict isolation of HCV-positive patients, dedicated dialysis machines and nursing staff at new dialysis set-up could possibly be the reasons of relatively low anti-HCV positivity at the current study than that reported by Shaheen et al., from four centres in the western region of KSA, (72.3%) and that by Huraib et al., in their multi-centre study in KSA, (68%) as well as the mean national rate. On the other hand, the use of more sensitive third generation enzyme - linked immunosorbent assay (ELISA) technique, long duration on HD, multiple blood transfusions, patients with dialysis treatment in multi-centres, factors related to infrastructure, environment and operational system might be responsible for the high prevalence of anti-HCV found in this study than that reported by Saeed et al., from Riyadh and those observed in the central region of KSA. Although routes of transmission are still unclear, early detection of all infected patients is mandatory for HCV prophylaxis in HD patients. Furthermore, an intensive educational program for staff members, HD patients and proper evaluation of the HD situation are needed. Thus, observation of appropriate preventive measures by all HD-centres is paramount.

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[No Title Available]

Abstract: A survey was conducted in the hemodialysis population of the state of Tocantins, Brazil, aiming

Cited by 30 publications

References 37 publications

Prevalence of asymptomatic hepatitis B virus and hepatitis C virus infections in patients with maintenance hemodialysis of a tertiary care hospital in western Maharashtra

Prevalence of asymptomatic hepatitis B virus and hepatitis C virus infections in patients with maintenance hemodialysis of a tertiary care hospital in western Maharashtra

Prevalence and Risk Factors of HCV Infection among Haemodialysis Patients at Dialysis Centers in Khartoum State - Sudan

Hepatitis C Infection in Hemodialysis Patients, Makkah, Saudi Arabia

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