Comparação da espessura da perimatriz, de colesteatomas adquiridos, entre pacientes pediátricos e adultos

Dornelles, Cristina; Costa, Sady Selaimen da; Meurer, Luíse; Schweiger, Cláudia

doi:10.1590/s0034-72992005000600017

Cited by 6 publications

(9 citation statements)

References 20 publications

(18 reference statements)

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“…When looking at the hematoxylin-eosin stained specimens in an optical microscope, it was clear that cholesteatomas consist of keratinized squamous stratified epithelium, with four layers identical to those of thin skin (basal, squamous, granulous, and stratum corneum), lying on a bed of connective tissue that contains fibroblasts, lymphocytes, plasmacytes, and e macrophages. These findings were compatible with those of other authors that looked into cholesteatoma histopathology 1 , 4 , 6 . There is some divergence as to the best nomenclature for cholesteatoma epithelium and the connective tissue it lies on.…”

Section: Discussionsupporting

confidence: 93%

“…This study included 50 cholesteatoma fragments. Other authors that analyzed a similar case base were Pereira 4 and Dornelles 6 , with 31 and 74 cholesteatomas respectively.…”

Section: Discussionmentioning

confidence: 98%

“…The following histopathologic patterns were assessed: perimatrix inflammatory process, atrophy, acanthosis, basal layer hyperplasia, and formation of epithelial cones in the matrix. These patterns were assessed qualitatively (absent and present) and, when present, were analyzed semi-quantitatively and graded in mild, moderate, and severe depending on their intensity 4 , 6 .…”

Section: Discussionmentioning

confidence: 99%

“…Cholesteatomas may present various histological patterns such as atrophy, acanthosis, basal layer hyperplasia, and presence of epithelial cones 4 , 6 , 7 .…”

Section: Introductionmentioning

confidence: 99%

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Analysis of histopathological aspects in acquired middle ear cholesteatoma

Alves

Pereira

Ribeiro

et al. 2008

Brazilian Journal of Otorhinolaryngology

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Section: Discussionsupporting

confidence: 93%

“…This study included 50 cholesteatoma fragments. Other authors that analyzed a similar case base were Pereira 4 and Dornelles 6 , with 31 and 74 cholesteatomas respectively.…”

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

“…Cholesteatomas may present various histological patterns such as atrophy, acanthosis, basal layer hyperplasia, and presence of epithelial cones 4 , 6 , 7 .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Analysis of histopathological aspects in acquired middle ear cholesteatoma

Alves

Pereira

Ribeiro

et al. 2008

Brazilian Journal of Otorhinolaryngology

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“…Cholesteatomas may present various histological patterns such as atrophy, acanthosis, basal layer hyperplasia, and presence of epithelial cones 4,6,7 .…”

Section: Introductionmentioning

confidence: 99%

Análise dos padrões histopatológicos do colesteatoma adquirido da orelha média

Alves¹,

Pereira²,

Ribeiro

et al. 2008

Rev. Bras. Otorrinolaringol.

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Mi ddle ear cholesteatomas are characterized by the presence of stratified squamous epithelium in this cavity with highly invasive properties causing bone destruction and it may lead to complications. Aim: To study the histopathological features in acquired cholesteatomas of the middle ear, correlating this data with patient age. Study design:clinical and experimental cross-sectional study. Material and Methods: Samples were obtained from 50 patients submitted to otologic surgery for the removal of middle ear cholesteatomas from 2006 to 2007. Thirty four patients were adults and 16 were children. Samples were studied by histological analysis. Results: we found the presence of epithelial atrophy (78%), epithelial acanthosis (88%), hyperplasia of the basal layer (88%) and formation of epithelial cones (62%). There was a positive and significant correlation between histopathological variables (such as epithelial acanthosis, hyperplasia of the basal layer and formation of epithelial cones). Histopathological variables presented no statistical significant difference in both age groups (p>0,05). Conclusion: Cholesteatomas have hyperproliferating characteristics with epithelial acanthosis, hyperplasia of the basal layer and the presence of epithelial cones in the matrix.

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Tympanomastoidectomy for cholesteatoma among Nigerians

Olusesi

Opaluwah

2013

Eur Arch Otorhinolaryngol

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The incidence of cholesteatoma among Nigerians is not well documented, as is the outcome of surgical treatment. A descriptive analysis of prospectively collected data of cases of cholesteatoma managed with tympanomastoidectomy at National Hospital Abuja between September 2005 and April 2012 is presented. Cases were analyzed for age, sex, type of cholesteatoma, intra-operative findings, and post-operative outcome after 6 months of follow up. A total of 28 ears from 25 cases of cholesteatoma had tympanomastoidectomy. Age range was 6-73 years (mean = 34.4, SD = 18.67). There were 13 females and 12 males. Primary acquired cholesteatoma was seen in 18 cases (20 ears), secondary acquired in 5 cases (six ears), and external auditory canal cholesteatoma was seen in 2 cases (two ears). The sites involved in middle ear cholesteatoma was attic, sinus and mesotympanum pars tensa (16/26), attic, sinus, antrum and mastoid cavity (5/26), attic, sinus, mesotympanum and mastoid antrum (4/26), and attic only (3/26).21/25 of cases (24 ears) managed had single stage intact canal wall (ICW) tympanomastoidectomy, while 4/25 (4 ears) had two-stage surgery with canal wall down tympanomastoidectomy in two of these, and revision surgery done within 12 months of first surgeries. 2/25 cases (in the two stage revision group) had postoperative persistent mastoid cutaneous fistula and were treated with post-auricular advancement flap. The commonest cholesteatoma type seen at National Hospital Abuja, Nigeria was primary acquired type, and involved the attic, sinus and mesotympanum pars tensa mainly, and most can be managed by single stage tympanomastoidectomy.

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Comparação da espessura da perimatriz, de colesteatomas adquiridos, entre pacientes pediátricos e adultos

Cited by 6 publications

References 20 publications

Analysis of histopathological aspects in acquired middle ear cholesteatoma

Analysis of histopathological aspects in acquired middle ear cholesteatoma

Análise dos padrões histopatológicos do colesteatoma adquirido da orelha média

Tympanomastoidectomy for cholesteatoma among Nigerians

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