Restless legs syndrome associated with cardiac failure and aggravated after valvular replacement: Vesper's curse?

Rodrigues, Raimundo Nonato; Rodrigues, Aída Alexandra Alvim de Abreu e Silva; Corso, Jeana Torres; Peixoto, Thaisa Fabiana

doi:10.1590/s0004-282x2008000400019

Cited by 3 publications

(3 citation statements)

References 11 publications

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“…Men with RLS, compared to individuals without RLS, have higher mortality independent to other known risk factors such as cancer, cardiovascular disease and hypertension 23 . 24,25,26,27,28 In a recent review of drug induced RLS, all studies that evaluated induction or exacerbation of RLS were considered as level IV evidence 29 . The vast majority of studies did not control additional risk factors, eg, concomitant use of alcohol, tobacco or caffeine.…”

Section: Epidemiologymentioning

confidence: 99%

Brazilian consensus on guidelines for diagnosis and treatment for restless legs syndrome

Fröhlich

Éckeli

Bacelar³

et al. 2015

Arq. Neuro-Psiquiatr.

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Section: Epidemiologymentioning

confidence: 99%

Brazilian consensus on guidelines for diagnosis and treatment for restless legs syndrome

Fröhlich

Éckeli

Bacelar³

et al. 2015

Arq. Neuro-Psiquiatr.

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“…[7][8][9] Alternately, recent studies suggest that RLS is associated with the risk of cardiovascular diseases, musculoskeletal pain, osteoporosis, and ultimately increased mortality in hemodialysis patients. [10][11][12][13][14] Regarding RLS treatment, two therapeutic approaches can be suggested including pharmacological and non-pharmacological therapies. 2 Common pharmacological agents for the treatment of RLS include levodopa, opioids, anticoagulants, benzodiazepines, and drugs such as clonidine.…”

mentioning

confidence: 99%

Investigating the Effect of Temperature Therapy on the Severity of Restless Legs Syndrome: Systematic Review and Meta-Analysis

MOHAMMADI,

VAISI RAYGANI

2023

Clin Med Res

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Background: Restless legs syndrome (RLS) is a sensorimotor disorder leading to disturbance of resting, discomfort, stress, and impaired daytime activity in the sufferers. The present systematic review and meta-analysis was conducted to determine the effect of temperature therapy on the severity of RLS. Methods:The electronic databases of Google Scholar, ProQuest, Scopus, PubMed, Web of Science, and State Inpatient Databases (SID) were searched from inception to August 2022. The Cochrane Collaboration's Risk of Bias Tool was used to check the quality of included studies. Meta-analysis was performed by calculating standardized mean differences (SMDs), using random effects model, and running Comprehensive Meta-Analysis (CMA) software version 2. Results:The included studies (n=6) comprised 177 participants, whose mean age was 49.85 years old. The results of the meta-analysis showed temperature therapy could reduce the severity of RLS (SMD=-1.520, 95% CI: -2.122 to -0.918). Regarding the source of heterogeneity, meta-regression results indicated the efficacy of the intervention in reducing the severity of RLS enhanced significantly by increasing the duration of the intervention in each session (β=-0.039, 95% CI -0.076 to -0.002, P<0.001). The results also showed increasing the duration (β=-0.039, 95% CI -0.076 to -0.002, P<0.001) and the temperature of the intervention in each session (β=-0.016, 95% CI -0.028 to -0.003, P<0.05) significantly enhanced the efficacy of the intervention in reducing the severity of RLS. The results also indicated that, among patients with underlying clinical conditions, the effectiveness of temperature therapy was higher in hemodialysis patients (β=-2.006, 95% CI -2.736 to -1.276, P<0.05). Conclusion:The present study findings suggested temperature therapy could mildly reduce the severity of RLS symptoms. It was also found that the highest efficacy of this intervention could be achieved when the higher temperature was used in fewer treatment sessions in hemodialysis patients. Based on our findings, this intervention can be included in the care plan of patients with RLS considering the settings described to achieve the highest efficacy.

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“…1 Evidence suggests that RLS in hemodialysis patients is associated with a risk of cardiovascular disease, osteoporosis, musculoskeletal pain, and increased mortality. [4][5][6][7][8] In the general population and in patients with end-stage renal disease (ESRD), the potential causes of RLS include anemia, pregnancy, iron deficiency, the dysfunction of dopamine within the central nervous system, a family history of RLS, and peripheral neuropathy. 9,10 In patients with ESRD, iron deficiency, anemia, and dialysis are predisposing factors that can lead to RLS.…”

mentioning

confidence: 99%

Effect of Near-Infrared Light Therapy Based on Acupoints on the Severity of Restless Legs Syndrome in Patients Undergoing Hemodialysis: A Single-Blind, Randomized Controlled Trial

Mohammadi¹,

Raygani²,

Ghobadi³

et al. 2018

Clin Med Res

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Restless legs syndrome associated with cardiac failure and aggravated after valvular replacement: Vesper's curse?

Cited by 3 publications

References 11 publications

Brazilian consensus on guidelines for diagnosis and treatment for restless legs syndrome

Brazilian consensus on guidelines for diagnosis and treatment for restless legs syndrome

Investigating the Effect of Temperature Therapy on the Severity of Restless Legs Syndrome: Systematic Review and Meta-Analysis

Effect of Near-Infrared Light Therapy Based on Acupoints on the Severity of Restless Legs Syndrome in Patients Undergoing Hemodialysis: A Single-Blind, Randomized Controlled Trial

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