Effect of Near-Infrared Light Therapy Based on Acupoints on the Severity of Restless Legs Syndrome in Patients Undergoing Hemodialysis: A Single-Blind, Randomized Controlled Trial

Mohammadi, Mohammad Mehdi; Raygani, Ali Akbar Vaisi; Ghobadi, Akram; Samadzadeh, Soheila; Salari, Nader

doi:10.3121/cmr.2018.1389

Cited by 14 publications

(10 citation statements)

References 34 publications

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“…In a single-blind, randomized controlled trial, 60 hemodialysis patients with RLS received 12 sessions of near infrared (940 nm) treatment to acupoints in the lower limb 3 times a week. In this study, clinically significant improvement was observed, but upon discontinuation the effect was diminished (35). Describing 2 cases with RLS who were treated with acupuncture, Fukutome (36) reported that 4W-acuinjection in Zulinqi (GB41), Kunlun (BL60), Zusanli (ST36), and Sanyinjiao (SP6) acupoints led to immediate relief in the form of a calm sensation and cessation of involuntary movements in legs.…”

Section: Ying Deficiency and Yang Stagnation Leads To Symptomsmentioning

confidence: 65%

Effectiveness of acupuncture in the management of restless leg syndrome: a systematic review and meta-analysis

Huang¹,

Tang²,

Sun³

et al. 2021

Ann Palliat Med

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Section: Ying Deficiency and Yang Stagnation Leads To Symptomsmentioning

confidence: 65%

Effectiveness of acupuncture in the management of restless leg syndrome: a systematic review and meta-analysis

Huang¹,

Tang²,

Sun³

et al. 2021

Ann Palliat Med

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“…Non-pharmacologic treatment by pneumatic-compression devices or near-infrared light therapy can improve microvascular circulation during the night to relieve RLS symptoms (58,84,85). Standard acupuncture may be another safe alternative treatment (86).…”

Section: Treatmentmentioning

confidence: 99%

Circadian rhythm in restless legs syndrome

Tang

Sun²,

Zhang³

et al. 2023

Front. Neurol.

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Restless legs syndrome (RLS) is a sensorimotor disorder with a obvious circadian rhythm, as its symptoms often occur or worsen only in the evening or at night. The mechanisms behind the rhythms of RLS have not yet been fully elucidated. This review explores possible causes for the circadian fluctuations of the symptomatology, including the levels of iron, dopamine, melatonin, melanocortin, and thyroid-stimulating hormone in the brain, as well as conditions such as peripheral hypoxia and microvascular function disorders. The metabolic disturbances of the substances above can create a pathological imbalance, which is further aggravated by physiological fluctuations of circadian rhythms, and results in the worsening of RLS symptoms at night. The review concludes with the suggestions for RLS treatment and research directions in the future.

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“…Song et al conducted a metanalysis on the effect of exercise on RLS, fatigue, depression and sleeping quality in hemodialysis patients, and he reported that exercise can be effective in improving symptoms of RLS (P < 0.001), fatigue (P < 0.001) and depression (P < 0.001) [ 36 ]. Mohammadi et al performed a single-blind, randomized controlled trial, and he found that near-infrared light can decrease symptoms of RLS in hemodialysis patients [ 37 ]. Kahvecioglu et al declared that there is an improvement of RLS in hemodialysis patients after renal transplantation and normalization of the kidney functions [ 38 ].…”

Section: Reviewmentioning

confidence: 99%

Dialysis Patients With Restless Leg Syndrome: Can We Relieve Their Suffering?

Salib¹,

Memon²,

Gowda³

et al. 2020

Cureus

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Restless leg syndrome (RLS), also called Willis Ekbom disease, can be described as an unpleasant feeling that intensely urges the patients to move their lower limbs. RLS is classified into primary and secondary. It is one of the common complications in hemodialysis patients, and it impairs patients' quality of life. Unfortunately, it is an underdiagnosed and undertreated disorder. In this review article, we performed a literature search using the PubMed database to compare different treatment modalities for RLS in patients with end-stage renal disease (ESRD) on regular hemodialysis. Many of the non-pharmacologic modalities of treatment are cost-effective and safer than pharmacologic therapy. Given the small sample size of the studies and short follow up duration, we should consider conducting studies on a larger number of patients and for longer periods of time to assess the efficacy and safety of different treatment patterns for RLS in hemodialysis patients. We hope to raise awareness about this neurologic condition in hemodialysis patients.

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Effect of Near-Infrared Light Therapy Based on Acupoints on the Severity of Restless Legs Syndrome in Patients Undergoing Hemodialysis: A Single-Blind, Randomized Controlled Trial

Abstract: The present study showed that the application of NIR light to acupoints in the legs and feet was as an effective treatment for attenuating the symptoms of RLS in hemodialysis patients.

Cited by 14 publications

References 34 publications

Effectiveness of acupuncture in the management of restless leg syndrome: a systematic review and meta-analysis

Effectiveness of acupuncture in the management of restless leg syndrome: a systematic review and meta-analysis

Circadian rhythm in restless legs syndrome

Dialysis Patients With Restless Leg Syndrome: Can We Relieve Their Suffering?

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