Neuropatia periférica e miosite na síndrome hipereosinofílica idiopática: relato de caso

Scola, Rosana Hermínia; Trentin, Ana Paula; Fabiani, G; Mücke, D; Werneck, Lineü Cesar

doi:10.1590/s0004-282x2004000100027

Cited by 3 publications

(1 citation statement)

References 12 publications

(29 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Eosinophilia is a rare finding in neuromuscular disorders (NMDs) but has occasionally been reported in some of them [1, 2, 3, 4]. Excellent overviews of NMDs with eosinophilia have been provided by Schröder et al [5] and Pellissier et al [6].…”

Section: Introductionmentioning

confidence: 99%

Multisystem Disease, Including Eosinophilia and Progressive Hyper-Creatine-Kinase-emia over 10 Years, Suggests Mitochondrial Disorder

Finsterer

Huber

2017

Case Rep Neurol

View full text Add to dashboard Cite

Background: Eosinophilia has not been reported as a manifestation of a mitochondrial disorder (MID). Here, we report a patient with clinical features suggesting a MID and permanent eosinophilia, multisystem disease, and progressive hyper-creatine-kinase (CK)-emia for at least 10 years. Materials and Methods: Methods applied included a clinical exam, blood chemical investigations, electrophysiological investigations, imaging, and invasive cardiological investigations. The patient was repeatedly followed up over several years. He required replacement cardiac surgery. Results: In a 57-year-old male, eosinophilia was first detected at the age of 44 years and has remained almost constantly present until today. In addition to eosinophilia, he developed progressive hyper-CK-emia at the age of 47 years. His history was further positive for hepatopathy, hyperlipidemia, hypothyroidism, renal insufficiency, spontaneous Achilles tendon rupture, double vision, exercise intolerance, muscle aching, mild hypoacusis, sensory neuropathy, seizures, and mitral insufficiency/stenosis requiring valve replacement therapy, oral anticoagulation, and pacemaker implantation. Based on the multisystem nature of his abnormalities and permanent hyper-CK-emia, a MID was suspected. Conclusion: Eosinophilia can be associated with a MID with myopathy, possibly as a reaction to myofiber necrosis. If eosinophilia is associated with progressive hyper-CK-emia and multisystem disease, a MID should be suspected.

show abstract

Section: Introductionmentioning

confidence: 99%

Multisystem Disease, Including Eosinophilia and Progressive Hyper-Creatine-Kinase-emia over 10 Years, Suggests Mitochondrial Disorder

Finsterer

Huber

2017

Case Rep Neurol

View full text Add to dashboard Cite

show abstract

Eosinophilia-associated muscle disorders: an immunohistological study with tissue localisation of major basic protein in distinct clinicopathological forms

et al. 2009

View full text Add to dashboard Cite

MBP immunohistology on skeletal muscle, previously performed only for acute eosinophilic polymyositis, suggests that eosinophil-mediated injury of muscle cells may occur in a wider spectrum of less aggressive eosinophilia-associated myopathies than previously thought. As conventional histology is likely to underestimate this leucocyte subset, MBP staining may be a useful tool in the analysis of tissue infiltration of eosinophils as a possible treatment target.

show abstract

Ulnar mononeuropathy associated with eosinophilia

Kumar

Sodhi

2012

Paediatrics and International Child Health

View full text Add to dashboard Cite

Neuropatia periférica e miosite na síndrome hipereosinofílica idiopática: relato de caso

Cited by 3 publications

References 12 publications

Multisystem Disease, Including Eosinophilia and Progressive Hyper-Creatine-Kinase-emia over 10 Years, Suggests Mitochondrial Disorder

Multisystem Disease, Including Eosinophilia and Progressive Hyper-Creatine-Kinase-emia over 10 Years, Suggests Mitochondrial Disorder

Eosinophilia-associated muscle disorders: an immunohistological study with tissue localisation of major basic protein in distinct clinicopathological forms

Ulnar mononeuropathy associated with eosinophilia

Contact Info

Product

Resources

About