Incidence of endophthalmitis after cataract surgery (2002-2008) at a Brazilian university-hospital

Melo, Gustavo Barreto; Bispo, Paulo José Martins; Regatieri, Caio V.; Yu, Maria Cecília Zorat; Pignatari, Antônio Carlos Campos; Hofling-Lima, Ana Luísa

doi:10.1590/s0004-27492010000600007

Cited by 23 publications

(19 citation statements)

References 11 publications

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“…This may also account for the large number of patients who had already undergone some treatment, either clinical or surgical, which in turn may explain the large number of patients who did not have material collected for culture when getting to the our service, or who presented a negative result of culture. Among the positive cultures, there was a predominance of gram positive microorganisms, as in other studies 1,2,4,6 . The delay in the diagnosis and appropriate treatment can also justify the long hospitalization and the poor visual outcome found in our study.…”

Section: Discussionsupporting

confidence: 78%

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Endophthalmitis prevalence in an university hospital

Coelho¹,

Souza²,

Tanure³

2015

Revista Brasileira De Oftalmologia

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Section: Discussionsupporting

confidence: 78%

“…As it is a devastating condition 6 , the rapid and accurate diagnosis is essential for a proper and early treatment, which is initially established empirically, until there are the culture results and the necessary adjustments 2 .…”

mentioning

confidence: 99%

Endophthalmitis prevalence in an university hospital

Coelho¹,

Souza²,

Tanure³

2015

Revista Brasileira De Oftalmologia

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“…An incidence of 1.11 per 1,000 surgeries in the USA has been reported [6], 0.48 per 1,000 surgeries in Sweeden [7], 1.4 per 1,000 surgeries in Canada [8], and 0.49 per 1,000 surgeries in Brazil [9]. Visual outcome after endophthalmitis is generally poor; half the patients of the Endophthalmitis Vitrectomy Study achieved a visual acuity of 20/40 or better by 9 months after treatment [10].…”

Section: Discussionmentioning

confidence: 99%

The effect of ketorolac on biofilm of Staphylococcus epidermidis isolated from post-cataract endophthalmitis

Rossetti¹,

D’Alessandro²,

Pellegrino

et al. 2012

J Ophthal Inflamm Infect

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Purpose The purpose of this study is to investigate the effect of ketorolac on biofilm formation of Staphylococcus epidermidis isolated from patients with post-cataract endophthalmitis. Methods Forty S. epidermidis strains isolated from postoperative endophthalmitis were used for this study. Biofilms were grown on microtitre plates for 24 h, dyed, and stained with crystal violet. The mean optical density (OD) and the OD ratio (ODr = OD of the treated biofilm/OD of the untreated biofilm) were used for quantification. The biofilms were incubated with 13 mM ketorolac and without ketorolac for controls. Results The biofilm ODs of the S. epidermidis isolates untreated and treated with ketorolac were significantly different (0.335 ± 0.06 versus 0.158 ± 0.03, respectively; mean ± SD; P < 0.001). Ketorolac reduced S. epidermidis biofilm formation by 47.6 %. Conclusions Ketorolac, at a concentration of 13 mM, significantly reduces the formation of biofilm by strains of S. epidermidis that caused endophthalmitis.

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“…Most series report on an incidence rate ranging from 0.05% to 0.4% in different studies worldwide (Melo et al, 2010;Taban et al, 2005). Infectious endophthalmitis is defined as infection causing severe inflammation involving both the anterior and posterior segments of the eye after intraocular surgery.…”

Section: Endophthalmitismentioning

confidence: 99%