Fatores relacionados à fidelidade ao tratamento do glaucoma: opiniões de pacientes de um hospital universitário

Silva, Lucas Ravagnani; Paula, Jayter Silva; Rocha, Eduardo Melani; Rodrigues, Maria de Lourdes Veronese

doi:10.1590/s0004-27492010000200003

Cited by 20 publications

(14 citation statements)

References 19 publications

(23 reference statements)

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“…It is reasonable to suggest that patients may be more inclined to comply with an agent with a favorable tolerability profile than with one that causes discomfort. In fact, a positive relationship between tolerability and patient adherence has been suggested in several glaucoma publications 8–11. This hypothesis, however, remains to be tested in a rigorous manner.…”

Section: Discussionmentioning

confidence: 98%

Efficacy and tolerability of the fixed combination of brinzolamide 1% and timolol 0.5% in daily practice

Lanzl¹,

Raber²

2011

OPTH

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Introduction:The purpose of this study was to document the efficacy and tolerability of the new fixed-combination (FC) brinzolamide 1%/timolol 0.5% as used in daily practice throughout Germany.Methods:An open-label, multicenter, observational study of patients was performed that evaluated the transition from prior medication to brinzolamide/timolol FC for the reduction of intraocular pressure (IOP). Ophthalmologists measured IOP at baseline and 4–6 weeks after transition and assessed their satisfaction with brinzolamide/timolol FC. Patients assessed the tolerability of both their previous and new regimens, judged their satisfaction with brinzolamide/timolol, and reported their preference between their previous and new regimens. Patients transitioning from other FC products to brinzolamide/timolol FC were analyzed separately.Results:Data from 14,025 patients from 1161 centers were analyzed. Four to 6 weeks after transition to brinzolamide/timolol, patients experienced a mean IOP decrease of 3.9 ± 4.3 mm Hg (P < 0.0001). All of the predefined patient subgroups (grouped by previous therapy) demonstrated a significant mean IOP reduction following transition to brinzolamide/timolol (P < 0.0001). Patients judged brinzolamide/timolol tolerability more positively than they did their previous therapies (87.2% vs 53.7% favorable assessments) and reported a high satisfaction rating with brinzolamide/timolol (93.4%). Brinzolamide/timolol was preferred over previous therapy at a ratio of almost 9:1. Patients who transitioned from dorzolamide/timolol to brinzolamide/timolol (n = 2937) demonstrated a significant decrease in mean IOP (P < 0.0001), rated brinzolamide/timolol more tolerable than dorzolamide/timolol (88.9% vs 28.9%), and preferred brinzolamide/timolol at a ratio of more than 9:1. Patients who transitioned from brimonidine/timolol (n = 209) demonstrated a significant decrease in mean IOP (P < 0.0001), rated brinzolamide/timolol more tolerable (86.5% vs 32.1%), and preferred brinzolamide/timolol at a ratio of 11.5:1.Conclusions:The FC brinzolamide 1%/timolol 0.5% produced better IOP control than all previous therapies analyzed and demonstrated favorable tolerability and a high satisfaction rating, resulting in a strong patient preference for brinzolamide/timolol over previous therapies.

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Section: Discussionmentioning

confidence: 98%

Efficacy and tolerability of the fixed combination of brinzolamide 1% and timolol 0.5% in daily practice

Lanzl¹,

Raber²

2011

OPTH

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“…Questions associated with the collective can be more appropriately explored by using qualitative or qualitative and quantitative methodologies, such as CSD; this is required mainly to study the perceptions of people in general about a certain subject and more particularly about the control group, that is, the group of patients, in order to assess their perspectives about their disease (10)(11)(12) . This type of methodology has more often been used in ophthalmology (13)(14)(15) and in speech therapy (8,16,17) .…”

Section: Methodsmentioning

confidence: 99%

Comunicação em adultos surdocegos com síndrome de Usher: estudo observacional retrospectivo

Figueiredo

Chiari

Goulart

2013

CoDAS

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OBJETIVO: Conhecer as características e desafios enfrentados por surdocegos para comunicar-se e locomover-se; avaliar as repercussões da surdocegueira na vida dos sujeitos, especialmente em relação à comunicação e locomoção. MÉTODOS: Relato de série de casos realizado a partir de entrevistas semiestruturadas com questões relativas à funcionalidade da comunicação, com indivíduos com diagnóstico clínico de síndrome de Usher que frequentaram um ambulatório especializado em um serviço universitário, durante o ano de 2007. A amostra foi composta por 11 sujeitos surdocegos portadores da síndrome de Usher, com idades entre 20 e 57 anos (média de 43 anos e DP=12,27), dos quais 7 (63,6%) eram do gênero feminino. As respostas foram analisadas qualiquantitativamente pela técnica do Discurso do Sujeito Coletivo (DSC). RESULTADOS: Todos os entrevistados referiram que os sintomas visuais e auditivos tiveram início na infância. Dos 11 entrevistados, 6 sentiram que a doença afetou negativamente suas atividades cotidianas, 6 sentiram dificuldade no trabalho, 2 no lazer. Quatro relataram que houve mudança no relacionamento familiar e 5 relataram que não houve mudança na interação com a família e com os amigos. Na análise do discurso, quase 30% dos entrevistados relataram utilizar-se de formas alternativas de comunicação; 40% afirmaram deslocar-se sozinho se o trajeto for previamente conhecido. CONCLUSÃO: Os indivíduos com síndrome de Usher enfrentam situações desafiadoras nas atividades cotidianas, nos relacionamentos pessoais, no trabalho e no lazer. Formas alternativas de comunicação são muito utilizadas quando a comunicação oral não é possível. A maioria dos entrevistados referiu independência de locomoção, ou procurava alcançá-la.

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“…This study reveals evident lack of involvement of the community and unawa reness with regards to the importance of visual examination. It's a behavioral problem as observed previously in Brazil, for cataract and glaucoma treatment (29,30) . Given the parents' behavior towards free examinations and suitable health care services, it can be assumed that parents' initiative to spontaneously bring their children to be exa mined is less probable.…”

Section: Discussionmentioning

confidence: 66%

Validity of recall absent schoolchildren to free eye health projects

Noma

Carvalho

Kara‐José

2012

Arq. Bras. Oftalmol.

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Purpose: To analyze the results of recall absent schoolchildren to eye health projects. Methods: Crosssectional study. Visual screening was performed in schoolchildren attending 1 st to 4 th grades at public schools, from 7 to 10 yearsold, to select and forward to complete ophthalmic evaluation. The projects were performed during weekends, at a public school, in the same municipality. Free transportation, food and eyeglasses were offered. A second opportunity of examination was offered to the students who were absent from the first call, with the same facilities. Results: 51,509 schoolchildren had their vision tested, 14,651 (28.4%) were referred for ophthalmic examination. Of these, 8,683 (59.3%) attended the first call, 2,228 (37.3%) attended the recall and 25.5% of parents did not take their children to oph thalmic examination. The need for eyeglasses for children who attended the examination was 23.8% and 32.0% in the first opportunity and recall, respectively. The recall increased the coverage in 15.2% (59.3% to 74.5%). Conclusion: An expressive number of parents (25.5%) did not bring their children to be examined, even at a second opportunity of exam. The facilities offered: access, free examination, transportation and glasses. Children who were absent in the first opportunity and appeared at recall had a greater need for eyeglasses. Recall increa sed the coverage in 15.2% (59.3% to 74.5%) and it is not recommended when financial resources are limited.

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Fatores relacionados à fidelidade ao tratamento do glaucoma: opiniões de pacientes de um hospital universitário

Cited by 20 publications

References 19 publications

Efficacy and tolerability of the fixed combination of brinzolamide 1% and timolol 0.5% in daily practice

Efficacy and tolerability of the fixed combination of brinzolamide 1% and timolol 0.5% in daily practice

Comunicação em adultos surdocegos com síndrome de Usher: estudo observacional retrospectivo

Validity of recall absent schoolchildren to free eye health projects

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