Reproducibility of water drinking test performed at different times of the day

Section: Discussionsupporting

confidence: 93%

Reproducibility of the water drinking test in treated glaucomatous patients

Babić

Moraes

Hatanaka

et al. 2014

“…Peak IOP values (change of approximately 3 mmHg from baseline) were not significantly different before and after the LPI. These values were comparable to previous reports of peak IOP in normal eyes, and lower than those of patients with medically‐treated glaucoma (change of >5 mmHg) …”

Section: Discussionsupporting

confidence: 90%

“…These values were comparable to previous reports of peak IOP in normal eyes, 20 and lower than those of patients with medically-treated glaucoma (change of >5 mmHg). 20,21 The WDT is a stress test, which results in transient IOP increase following ingestion of 1000 mL of water (or 10 ml/kg water) during 5-15 min. One theory suggests that acute water intake results in a decrease in blood colloid osmotic pressure and subsequently shifts fluid into the choroidal space, as a result of an osmotic gradient.…”

Section: Discussionsupporting

confidence: 89%

Water‐drinking test in primary angle‐closure suspect before and after laser peripheral iridotomy

Waisbourd

Savant

Sun

et al. 2015

Background: This study aimed to investigate whether performing a laser peripheral iridotomy in primary angle-closure suspects had an effect on the intraocular pressure response during the water-drinking test.Design: Prospective study in a hospital setting.Participants: Primary angle-closure suspects scheduled for a laser peripheral iridotomy.Methods: Primary angle-closure suspects were evaluated before the laser peripheral iridotomy and 2 weeks after. On each visit, subjects underwent the waterdrinking test. Intraocular pressure was measured every 15 min within a 1-h period.Main Outcome Measures: Intraocular pressure fluctuations during the water drinking test.Results: Twenty patients were enrolled. The mean age was 58.1 years (±10.2 SD), predominantly female (n = 14, 70%). Average intraocular pressure range (maximum-minimum) during the waterdrinking test increased significantly from 2.6 ± 1.1 mmHg before the laser peripheral iridotomy to 3.5 ± 1.5 mmHg after (P = 0.04). The mean difference between peak and last intraocular pressure measurements increased after the laser peripheral iridotomy was performed, from 2.5 mmHg (±1.27 SD) to 3.3 mmHg (±1.66 SD), (P = 0.057). There was no change in mean peak intraocular pressure (maximum-baseline) before and after the laser peripheral iridotomy (P = 0.87).Conclusions: Primary angle-closure suspects who underwent the water-drinking test had a slightly more pronounced recovery of intraocular pressure after the laser peripheral iridotomy was performed, which may be attributed to increase in the area of exposed trabecular meshwork following treatment. Differences in intraocular pressure curves before and after laser peripheral iridotomy were minimal, and therefore, the water-drinking test had limited value as a provocative test in this patient population.

“…Medina et al 54 evaluated the reproducibility of WDT performed at different times of the day in POAG and normal individuals. The authors, based on levels of agreement, state a poor reproducibility of IOP peaks detected by the test, because 20% of glaucoma patients presented differences higher or equal to 3 mmHg among IOP peaks at different tests.…”

Section: Treatmentmentioning

confidence: 99%

Applications of the water drinking test in glaucoma management

Susanna

Clement

Goldberg

et al. 2017

Intraocular pressure (IOP) peaks and means have been considered important factors for glaucoma onset and progression. However, peak IOP detection depends only on appropriated IOP checks at office visits, whereas the mean IOP requires longitudinal IOP data collection and may be affected by the interval between visits. Also, IOP peak assessment is necessary to verify if the peak pressure of a given patient is in target range, to evaluate glaucoma suspect risk, the efficacy of hypotensive drugs and to detect early loss of IOP control. The water-drinking test has gained significant attention in recent years as an important tool to evaluate IOP peaks and instability. The main objective of this review was to present new findings and to discuss the applicability of the water-drinking test in glaucoma management.