Atuação do fisioterapeuta em unidades de terapia intensiva no contexto da pandemia de COVID-19

Guimarães, Fernando Silva

doi:10.1590/1980-5918.033.ed01

Cited by 23 publications

(21 citation statements)

References 2 publications

(6 reference statements)

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“…Abnormal chest X-rays are detected in roughly 60% of patients infected with SARS-CoV. It was reported that 20–30% of patients infected with SARS-COV require intensive care and mechanical ventilation [ [59] , [60] , [61] ]. In addition, at that time, it was noticed the SARS-CoV had developed high stability in aerosol and other surfaces, which had improved its transmissibility [ 62 , 63 ].…”

Section: The Pandemic Coronavirusesmentioning

confidence: 99%

The human pandemic coronaviruses on the show: The spike glycoprotein as the main actor in the coronaviruses play

Souza

Mesquita

Amaral

et al. 2021

International Journal of Biological Macromolecules

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Three coronaviruses (CoVs) have threatened the world population by causing outbreaks in the last two decades. In late 2019, the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged and caused the coronaviruses to disease 2019 (COVID-19), leading to the ongoing global outbreak. The other pandemic coronaviruses, SARS-CoV and Middle East respiratory syndrome CoV (MERS-CoV), share a considerable level of similarities at genomic and protein levels. However, the differences between them lead to distinct behaviors. These differences result from the accumulation of mutations in the sequence and structure of spike (S) glycoprotein, which plays an essential role in coronavirus infection, pathogenicity, transmission, and evolution. In this review, we brought together many studies narrating a sequence of events and highlighting the differences among S proteins from SARS-CoV, MERS-CoV, and SARS-CoV-2. It was performed here, analysis of S protein sequences and structures from the three pandemic coronaviruses pointing out the mutations among them and what they come through. Additionally, we investigated the receptor-binding domain (RBD) from all S proteins explaining the mutation and biological importance of all of them. Finally, we discuss the mutation in the S protein from several new isolates of SARS-CoV-2, reporting their difference and importance. This review brings into detail how the variations in S protein that make SARS-CoV-2 more aggressive than its relatives coronaviruses and other differences between coronaviruses.

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Section: The Pandemic Coronavirusesmentioning

confidence: 99%

The human pandemic coronaviruses on the show: The spike glycoprotein as the main actor in the coronaviruses play

Souza

Mesquita

Amaral

et al. 2021

International Journal of Biological Macromolecules

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“…Their role extends from the early stages of preparation and adjustment of the ventilator, until intubation, weaning, and extubation. 59 , 60 Physical therapists also develop procedures to prevent and/or treat common complications observed in ICU patients, such as neuropathy, myopathy, contractures, thrombosis, and postural instability. 10 , 11 …”

Section: Resultsmentioning

confidence: 99%

“…Therefore, most if not all patients with severe cases of COVID-19 require oxygen therapy or invasive mechanical ventilation (IMV), which in turn demands intensive physical therapy. 59 …”

Section: Resultsmentioning

confidence: 99%

COVID-19: the importance of physical therapy in the recovery of workers’ health

Paz¹,

Bezerra²,

Pereira³

et al. 2021

Rev Bras Med Trab

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Coronavirus disease 2019 (COVID-19) is likely to have a major impact on society and the economy since the illness is currently infecting a significant number of active workers in the industry and service sectors. The illness can have long-term consequences for patients, affecting their functional capacity and, consequently, their occupational performance. This study analyzed the effects of COVID-19 on occupational health, with a focus on the importance of physical therapy in rehabilitation. An integrative literature review was conducted based on articles retrieved from the PubMed, SciELO, and LILACS databases using the following keywords: COVID-19, physical therapy, rehabilitation, and occupational health. The search retrieved 1,308 studies, 15 of which met inclusion criteria for the review. A thorough assessment of the articles revealed four topics that corresponded to the results of this study: 1) effects of COVID-19 on occupational health; 2) physical therapy in mild and moderate cases without hospitalization; 3) physical therapy in hospitalized patients with COVID-19; 4) physical therapy in post-intensive care unit (ICU) recovery and after hospital discharge. The findings showed that COVID-19 can affect several physiological systems and have both short- and long-term effects on patients, including physical and psychological impairments. Physical therapists must be involved in the battle against this illness to help patients recover their physical function and return to work as quickly, safely, and effectively as possible.

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“…Daily monitoring of ventilatory parameters and respiratory mechanics recommended to avoid injury associated with MV. By calculating the predicted weight, it was possible to ventilate the patient safely, performing a VT of 6 to 8 ml/kg, low PAP in order to maintain P plato up to 28 cm H 2 O, and control of pulmonary distention pressure (drive pressure) below 15 cmH 2 O (13)(14)(15)(16).…”

Section: Discussionmentioning

confidence: 99%

COVID-19 and Sickle Cell Disease in PICU: Case Report

Tonial¹,

Miranda²,

Silva³

et al. 2020

Med Clin Res Open Access

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Sars-Cov 2 viral infection can cause an intense inflammatory reaction, hypoxemia and acute respiratory failure. The disease spreads more easily in chronic comorbidities, such as sickle cell anemia and overweight. Among the various professionals involved in the recovery of patients with Covid-19, the role of the physiotherapist stands out, not only for acting in the management of the disease but also for preventing and rehabilitating the respiratory deficiencies and the functional limitations caused by it. The present report aims to elucidate the multidisciplinary work carried out in the patient with overweight and sickle cell anemia during the period of hospitalization in the Pediatric Intensive Care Unit by Covid-19. This is an observational, longitudinal single-arm case report. The patient’s medical data collection was carried out retrospectively through record, including anamnesis reports, physical examination, and multi-professional procedures used from admission to discharge, including anamnesis reports, physical examination, and multi-professional procedures used from admission to discharge. The present study is a rare case of pediatric Covid-19 with severe signs and symptoms. The treatment performed by the multidisciplinary team resulted in a favorable outcome since the beginning of hospitalization. Physiotherapy, including early mobilization and rehabilitation may help prevent or mitigate sequelae related to bed rest, thus improving physical function and outcomes and reducing length of stay by increasing ventilator free-days.

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Atuação do fisioterapeuta em unidades de terapia intensiva no contexto da pandemia de COVID-19

Cited by 23 publications

References 2 publications

The human pandemic coronaviruses on the show: The spike glycoprotein as the main actor in the coronaviruses play

The human pandemic coronaviruses on the show: The spike glycoprotein as the main actor in the coronaviruses play

COVID-19: the importance of physical therapy in the recovery of workers’ health

COVID-19 and Sickle Cell Disease in PICU: Case Report

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