“…These protocols include several techniques such as manual dynamic activation (Virdee et al ), passive ultrasonic irrigation (Plotino et al , van der Sluis et al ), sonic irrigation (Karade et al , Zeng et al ), apical negative pressure irrigation (Gu et al , Tomson & Simon ), reciprocating activation (Kato et al ), laser activation with photon‐induced photo‐acoustic streaming (PIPS) (Arslan et al ), and irrigant activation using either XP‐endo finisher (FKG Dentaire, La Chaux de Fonds, Switzerland), self‐adjusting file system (SAF; ReDent Nova, Ra'anana, Israel), TRUShape (Dentsply Sirona, Ballaigues, Switzerland) or XP‐endo shaper (FKG Dentaire) (Siqueira et al ). In the literature, there is no consensus on the best irrigation protocol necessary for effective activation of the irrigant and the removal of smear layer and debris from the root canal (Rodrigues et al , Nakamura et al ).…”