2019
DOI: 10.1590/1806-9282.65.12.1433
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Elderly patients with glioblastoma: the impact of the surgical resection extent on survival

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Cited by 4 publications
(3 citation statements)
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“…Still, caution is advised in interpreting this finding owing to the high complication rate. 32 Despite these concerns, our retrospective data showed that decreased performance status or serious complications such as hemiparesis, aphasia, and declined mentality did not increase according to the EOR. This is evident because, in addition to GTR, a lobectomy was performed only in the noneloquent area in the nondominant lobe.…”
Section: Discussionmentioning
confidence: 64%
“…Still, caution is advised in interpreting this finding owing to the high complication rate. 32 Despite these concerns, our retrospective data showed that decreased performance status or serious complications such as hemiparesis, aphasia, and declined mentality did not increase according to the EOR. This is evident because, in addition to GTR, a lobectomy was performed only in the noneloquent area in the nondominant lobe.…”
Section: Discussionmentioning
confidence: 64%
“…Median OS was significantly longer in patients with GTR (10.8 months) compared with partial resection (PR) (8.1 months) or biopsy (3.0 months). A systematic review between 2005 and 2018 demonstrated that total resection was associated with longer postoperative OS (13.13 months) when compared with PR (7.52 months) or biopsy (2.56 months) in seven clinical studies ( 28 ). In an Italian cohort of 178 elderly patients, CR was seen in 8 patients (4.5%), GTR in 63 (35.4%), subtotal resection (STR) in 46 (25.8%), PR in 16 (9.0%) and biopsy in 45 (25.3%).…”
Section: Surgical Resectionmentioning
confidence: 99%
“…It is important to highlight that the EOR was the most robust influencing factor in the algorithm hierarchy, while age appeared at the third node of the CART algorithm, thus strengthening the role of surgery also in EGBM and performing patients (who have a high preoperative KPS score), when surgical planning allowed us to preoperatively estimate an EOR > 80%. 6,17,42 In a previous investigation, Flanigan et al elaborated a risk prognostic score in EGBM patients based on variables identified using the multivariate stepwise analysis (age, EOR, preoperative weakness, tumor size, and CCI). 1 A point designation was then given to each factor and points were totaled for each patient, considering only the presence of the variables and ruling out their interactions.…”
Section: Cart Analysismentioning
confidence: 99%