Retinol, β-carotene and oxidative stress in systemic inflammatory response syndrome

Abstract

Objective: patients suffering systemic inflammatory response syndrome (SIRS) constitute a group susceptible to elevated levels of oxidative stress. This study's aim is to evaluate the state of oxidative stress and levels of serum retinol and β-carotene in these patients. Methods: forty-six patients were divided into 2 groups: those those without diet (G1; n=18) and those with enteral nutritional support (G2; n=28). Serum levels of retinol and total carotenoids were measured. C-reactive protein (CRP) levels and Apache scores were also calculated. Oxidative stress was estimated by measuring thiobarbituric acid reactive substance (TBARS) levels. Results: the patients' median age was 66.9 (SD=19.3) years. Lower concentrations of retinol and carotenoids were found in 68.6 and 66.7% of G1, respectively. In G2, despite average vitamin A levels being 8078 + 4035, retinol and β-carotene were considered insufficient (31.2 and 33.4%, respectively). No difference was noted between the 2 groups, according to the variables studied, with the exception being PCR and β-carotene (p=0.002; p=0.01).

Periplaneta americana extract used in patients with systemic inflammatory response syndrome

“…The pathophysiological changes of SIRS have been clarifi ed in recent years. [9][10][11] Patients with SIRS are usually in a pathological state such as gastrointestinal mucosal ischemia and hypoxia, which lead to the appearance of mucosal lesions or mucosal barrier damage. At the same time, patient's body is in a high catabolic state and energy consumption is significantly increased; therefore nutritional support is particularly important in the treatment.…”

Oxygenic metabolism in nutritional obesity induced by olive oil. The influence of vitamin C

“…[46][47][48][49] Other substances, such as vitamin C in fruits and vegetables, have a positive effect on the protection against lipoperoxidation. 50,51 The aim of the present study is to analyze the situation of oxygenic metabolism in obesity and the endogenous and exogenous cytotoxicity induced by ROS in Wistar rats fed with liquid diets based on olive oil and supplemented with vitamin C for 30 days.…”