Repercussion of thyroid dysfunctions in thyroidology on the reproductive system: Conditio sine qua non?

Şengül, Demet; Şengül, İlker; Soares-Jr, José Maria

doi:10.1590/1806-9282.20220255

Cited by 10 publications

(2 citation statements)

References 13 publications

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“…Additionally, some data show that the pathogenic process might originate in the first trimester and that LMWH treatment can have benefits during implantation and placental development. This is why it may be important to evaluate the timing of the initiation of LMWH treatment, especially its introduction in the first trimester, which recommendation is also in accordance with our results as the participants were recruited in the late first or early in the second trimester 17 .…”

Section: Discussionsupporting

confidence: 82%

Hereditary thrombophilia and low -molecular -weight heparin in women: useful determinants, including thyroid dysfunction, incorporating the management of treatment and outcomes of the entity

Dugalić¹,

Petronijević

Şengül

et al. 2023

Rev. Assoc. Med. Bras.

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OBJECTIVE: Our study purposed to examine the complex relationship between low-molecular-weight heparin therapy, multiple pregnancy determinants, and adverse pregnancy outcomes during the third trimester in women with inherited thrombophilia. METHODS: Patients were selected from a prospective cohort of 358 pregnant patients recruited between 2016 and 2018 at the Clinic for Obstetrics and Gynecology, University Clinical Centre of Serbia, Belgrade. RESULTS: Gestational age at delivery (β=-0.081, p=0.014), resistance index of the umbilical artery (β=0.601, p=0.039), and d-dimer (β=0.245, p<0.001) between 36th and 38th weeks of gestation presented the direct predictors for adverse pregnancy outcomes. The model fit was examined using the root mean square error of approximation 0.00 (95%CI 0.00-0.18), the goodness-of-fit index was 0.998, and the adjusted goodness-of-fit index was 0.966. CONCLUSION: There is a need for the introduction of more precise protocols for the assessment of hereditary thrombophilias and the need for the introduction of low-molecular-weight heparin.

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Section: Discussionsupporting

confidence: 82%

Hereditary thrombophilia and low -molecular -weight heparin in women: useful determinants, including thyroid dysfunction, incorporating the management of treatment and outcomes of the entity

Dugalić¹,

Petronijević

Şengül

et al. 2023

Rev. Assoc. Med. Bras.

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“…Of note, the thyroid hormones are essential and crucial for endochondral ossification, chondrocyte maturation, and matrix synthesis. In fact, the evaluation of the articular cartilage using sonographic and pre-osteoarthritic evaluation of the knees with ultrasound possesses a prognostic value 2,[21][22][23] . Devrimsel et al 4 observed thinner femoral cartilage measurements in hypothyroid cases compared to the healthy volunteers.…”

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confidence: 99%

Revisiting femoral cartilage thickness in cases with Hashimoto's thyroiditis in thyroidology: a single institute experience

Yavuz

Dikbaş

Kulaklı

et al. 2023

Rev. Assoc. Med. Bras.

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OBJECTIVE: Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis or autoimmune thyroiditis, is a considerable part of the spectrum of chronic autoimmune thyroid gland disorders which is pathologically associated with various degrees of lymphocytic infiltration. The purpose of the present study was to evaluate whether cartilage thickness is affected in patients with Hashimoto's thyroiditis or not in thyroidology. METHODS: A total of 61 individuals had been evaluated in this case-control study, including 32 euthyroid Hashimoto's thyroiditis patients and 29 healthy subjects comparable in age, sex, and body mass index. The patients with a history of knee trauma or knee surgery, an additional systemic disease such as diabetes mellitus, or an inflammatory disease like rheumatoid arthritis, systemic lupus erythematosus, and scleroderma had not been included in the study. The thickness of the femoral articular cartilage was measured using B-mode ultrasonography, and the right lateral condyle, right intercondylar area, right medial condyle, left medial condyle, left intercondylar area, and left lateral condyle were also measured. RESULTS: No statistically significant difference between patients with Hashimoto's thyroiditis diagnosis and healthy controls in terms of age, age groups, gender, and body mass index (p>0.05). CONCLUSION: As a consequence, no obvious connection between autoimmune markers and cartilage thickness in patients with Hashimoto's thyroiditis was recognized. Although the diverse manifestation of Hashimoto's thyroiditis could be observed, it seems to be no liaison between thyroid autoimmunity and cartilage thickness.

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Highlighting early detection of thyroid pathology and gestational diabetes effects on oxidative stress that provokes preterm delivery in thyroidology: Does that ring a bell?

Dugalic,

Todorovic,

Sengul

et al. 2023

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Repercussion of thyroid dysfunctions in thyroidology on the reproductive system: Conditio sine qua non?

Cited by 10 publications

References 13 publications

Hereditary thrombophilia and low -molecular -weight heparin in women: useful determinants, including thyroid dysfunction, incorporating the management of treatment and outcomes of the entity

Hereditary thrombophilia and low -molecular -weight heparin in women: useful determinants, including thyroid dysfunction, incorporating the management of treatment and outcomes of the entity

Revisiting femoral cartilage thickness in cases with Hashimoto's thyroiditis in thyroidology: a single institute experience

Highlighting early detection of thyroid pathology and gestational diabetes effects on oxidative stress that provokes preterm delivery in thyroidology: Does that ring a bell?

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