Effects of Oral Oxytetracycline-Therapy on Wound Progression and Healing Following Aeromonas caviae Infection in Nile Tilapia (Oreochromis niloticus L.)

Roy, Anwesha; Abraham, Thangapalam Jawahar; Namdeo, Meshram Supradhnya; Singha, Jasmine; Julinta, Roy Beryl; Boda, Satyanarayana

doi:10.1590/1678-4324-2019180766

Cited by 9 publications

(6 citation statements)

References 28 publications

(38 reference statements)

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“…Oxytetracycline is a natural broad-spectrum antibiotic extensively used in global aquaculture due to its limited side effects in the host and broad-spectrum activity against both Gram-negative and Gram-positive bacteria, through the inhibition of protein syn-thesis [11][12][13]. In tilapia, OTC has been shown to successfully treat a range of bacterial diseases including Francisellosis, motile Aeromonas septicemia, and Streptococcosis, which are significant disease challenges for this sector [14][15][16]. Across the global aquaculture industry, OTC is often administered orally in the diet during disease outbreaks, where doses range 50 to 250 mg/kg/day for typically between four and eight days, up to 21 days, depending on the fish species and farming country [17,18].…”

Section: Introductionmentioning

confidence: 99%

Investigating the Effect of an Oxytetracycline Treatment on the Gut Microbiome and Antimicrobial Resistance Gene Dynamics in Nile Tilapia (Oreochromis niloticus)

et al. 2021

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Antibiotics play a vital role in aquaculture where they are commonly used to treat bacterial diseases. However, the impact of antibiotic treatment on the gut microbiome and the development of antimicrobial resistance in Nile tilapia (Oreochromis niloticus) over time remains to be fully understood. In this study, fish were fed a single treatment of oxytetracycline (100 mg/kg/day) for eight days, followed by a 14-day withdrawal period. Changes in the distal gut microbiome were measured using 16S rRNA sequencing. In addition, the abundance of antimicrobial resistance genes was quantified using real-time qPCR methods. Overall, the gut microbiome community diversity and structure of Nile tilapia was resilient to oxytetracycline treatment. However, antibiotic treatment was associated with an enrichment in Plesiomonas, accompanied by a decline in other bacteria taxa. Oxytetracycline treatment increased the proportion of tetA in the distal gut of fish and tank biofilms of the treated group. Furthermore, the abundance of tetA along with other tetracycline resistance genes was strongly correlated with a number of microbiome members, including Plesiomonas. The findings from this study demonstrate that antibiotic treatment can exert selective pressures on the gut microbiome of fish in favour of resistant populations, which may have long-term impacts on fish health.

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Section: Introductionmentioning

confidence: 99%

Investigating the Effect of an Oxytetracycline Treatment on the Gut Microbiome and Antimicrobial Resistance Gene Dynamics in Nile Tilapia (Oreochromis niloticus)

et al. 2021

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“…Monogeneans cause several problems in freshwater fish culture in Brazil, whether to produce animal protein or for ornamental purposes (Mota Vicente et al, 2021;Steckert et al, 2021). Therapeutic baths are widely used for the prevention and/ or treatment of diseases in fish culture, including salt, formalin, and essential oils (Hashimoto et al, 2016;García-Magaña et al, 2019;Roy et al, 2019).…”

Section: Resultsmentioning

confidence: 99%

Therapeutic bath of mint hydrolate in the control of monogenea for four tilapia species

et al. 2023

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This work aimed to evaluate a therapeutic bath of mint (Mentha x villosa) hydrolate in the control of monogeneans for four tilapia species (Oreochromis niloticus, Oreochromis aureus, Oreochromis mossambicus, and Oreochromis hornorum) reared in the same environment (pond). After two months, 60 individuals of O. niloticus were divided into six groups of ten fish each. Three of them were submitted to a 1-hour therapeutic bath of mint hydrolate at the concentration of 20 mL·L-1, and the others were used as a control group. This process was repeated for O. aureus, O. mossambicus and O. hornorum. After that, mucus and gills were analyzed to determine parasitological indices (prevalence, mean abundance, and mean intensity) for monogeneans. The efficacy of mint hydrolate bath was set as 73.5, 79, 80.7, and 84.5% for O. hornorum, O. aureus, O. mossambicus and O. niloticus, respectively,against the monogeneans in the mucus. All species in this work demonstrated similar parasitic susceptibility when reared in the same environment. In addition, the use of mint therapeutic bath demonstrated efficacy in the control of monogeneans in mucus for all evaluated species.

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“…Oral administration of Oxytetracycline and Sulfadimethoxine/Ormetoprim was recommended for MAS treatment 107,108 . In recent studies, Oxytetracycline and Ciprofloxacin were applied orally to treat A. hydrophila , A. caviae in Nile tilapia and common carp, C. carpio 109–112 . Ciprofloxacin and Streptomycin are also used to treat A. hydrophila and A. sobria in the farming of black tiger shrimp, Penaeus monodon .…”

Section: Overview Of Motile Aeromonas Infections In Fish Aquaculturementioning

confidence: 99%

Non‐antibiotic approaches to combat motile Aeromonas infections in aquaculture: Current state of knowledge and future perspectives

Dien

Ngo²,

Nguyen

et al. 2022

Reviews in Aquaculture

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Inland aquaculture contributed by three major fish groups, including carps, tilapias, and catfish plays a vital role in global food security and nutrition, particularly in low and middle-income countries. However, the sustainable development of this sector is hampered by disease epidemics, especially those caused by bacteria such as Aeromonas species. At least eight pathogenic motile Aeromonas species (A. hydrophila, A. veronii, A. jandaei, A. caviae, A. sobria, A. bestiarum, A. dhakensis and A. schubertii) have been reported in aquaculture with some causing up to 100% mortality during disease outbreaks. Simultaneously, emerging multidrug-resistant Aeromonas due to a long-inappropriate use of antibiotics is alarming and highlights a global public health concern and negative socioeconomic impacts. Here, we provide a comprehensive overview of motile Aeromonas infections, antibiotic use and antimicrobial resistance of Aeromonas species. This contribution also highlights the non-antibiotic approaches (the solutions for preventing or treating of bacterial diseases without resorting to antibiotic use) to control motile Aeromonas infections. In addition to the current state of knowledge and limitations of each prophylaxis/therapy, perspectives for future research are discussed critically, including oral/immersion multivalent vaccines, microencapsulated synbiotics, exogenous metabolites, and novel lytic bacteriophage cocktails. Some emerging applicable nanotechnology themes such as nanovaccines, nanobioactive compounds, and nanobubbles are also included in this review. In

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Effects of Oral Oxytetracycline-Therapy on Wound Progression and Healing Following Aeromonas caviae Infection in Nile Tilapia (Oreochromis niloticus L.)

Cited by 9 publications

References 28 publications

Investigating the Effect of an Oxytetracycline Treatment on the Gut Microbiome and Antimicrobial Resistance Gene Dynamics in Nile Tilapia (Oreochromis niloticus)

Investigating the Effect of an Oxytetracycline Treatment on the Gut Microbiome and Antimicrobial Resistance Gene Dynamics in Nile Tilapia (Oreochromis niloticus)

Therapeutic bath of mint hydrolate in the control of monogenea for four tilapia species

Non‐antibiotic approaches to combat motile Aeromonas infections in aquaculture: Current state of knowledge and future perspectives

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