Ecofriendly Synthesis of Silver Nanoparticles Using Potato Steroidal Alkaloids and Their Activity Against Phytopathogenic Fungi

Almadiy, Abdulrhman A.; Nenaah, Gomah E.

doi:10.1590/1678-4324-2018180013

Cited by 18 publications

(4 citation statements)

References 44 publications

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“…Besides, pure flavonoids are said to be mainly compound for the transformation of metallic ions to their nanostructures with enhanced anti-microbial and anti-cancer activities (Jain and Mehata, 2017 ). Similarly, alkaloids, tannins, and saponins have also been reported as green reducing agents to develop novel nanomaterials with versatile applications (Ahmad, 2014 ; Almadiy and Nenanaah, 2018 ; Choi et al, 2018 ). The schematic of BP-AgNPs synthesis is shown in Figure 1 .…”

Section: Resultsmentioning

confidence: 99%

Cytotoxic, Antimitotic, DNA Binding, Photocatalytic, H2O2 Sensing, and Antioxidant Properties of Biofabricated Silver Nanoparticles Using Leaf Extract of Bryophyllum pinnatum (Lam.) Oken

Chandraker

Lal

Dhruve

et al. 2021

Front. Mol. Biosci.

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Bryophyllum pinnatum is a perennial herb traditionally used in ethnomedicine. In the present report, silver nanoparticles (AgNPs) were synthesized using B. pinnatum leaf extract. BP-AgNPs were confirmed following UV-Vis spectroscopy with SPR peak at 412 nm and further characterized by FTIR, XRD, SEM-EDX, and TEM. Microscopic images confirmed the spherical shape and ~15 nm average size of nanostructures. BP-AgNPs were evaluated for photocatalytic degradation of hazardous dyes (methylene blue and Rhodamine-B) and showed their complete reduction within 100 and 110 min., respectively. BP-AgNPs have emerged as a unique SPR-based novel sensor for the detection of H2O2, which may deliver exciting prospects in clinical and industrial areas. DPPH and ABTS free radical scavenging activity were studied with respective IC50 values of 89 and 259 μg/mL. A strong intercalating interaction of CT-DNA with BP-AgNPs was investigated. Observed chromosomal abnormalities confirm the antimitotic potential of BP-AgNPs in the meristematic root tip. The cytotoxicity of BP-AgNPs against B16F10 (melanoma cell line) and A431 (squamous cell carcinoma cell line), was assessed with respective IC50 values of 59.5 and 96.61 μg/ml after 24 h of treatment. The presented green synthetic approach provides a novel and new door for environmental, industrial, and biomedical applications.

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Section: Resultsmentioning

confidence: 99%

Cytotoxic, Antimitotic, DNA Binding, Photocatalytic, H2O2 Sensing, and Antioxidant Properties of Biofabricated Silver Nanoparticles Using Leaf Extract of Bryophyllum pinnatum (Lam.) Oken

Chandraker

Lal

Dhruve

et al. 2021

Front. Mol. Biosci.

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“…Potato steroidal alkaloids and their nanoparticles were also found to be able to control the mycelial growth of phytopathogenic fungi including A. alternate , R. solani , Botrytis cinerea , and F. oxysporum . In another study, the alkaloid 1-corydalmine suppressed spore germination of A. brassicae and F. udum ( Basha et al, 2007 ; Almadiy and Nenaah, 2018 ). Alkaloids have been found to be capable of destroying cell walls and the membrane structures of fungal cells, thus achieving fungal inhibition ( Moraes et al, 2015 ; Wei et al, 2020 ).…”

Section: Discussionmentioning

confidence: 93%

Changes in the Soil Fungal Community Mediated by a Peganum harmala Allelochemical

Shi

Shao

2022

Front. Microbiol.

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Plants can release phytotoxic allelochemicals into the environment, not only to suppress other plants’ growth, but also alter community structure of soil microbiota, however, the mechanism are often complicated. We designed a consecutive cultivation procedure to evaluate the allelopathic effect of harmaline, the major active allelochemical produced by the desert plant Peganum harmala, on soil microorganisms. Harmaline was added to the soil at 20 μg/g, and after five generations of cultivation, the Chao1, Pielou, Shannon and Simpon indexes changed significantly. In particular, the relative abundances of the dominant fungi, Alternaria sp. and Fusarium sp., declined drastically by 84.90 and 91.90%, respectively. Further in vitro bioassays confirmed that harmaline indeed suppressed growth of 6 Alternaria and Fusarium strains isolated from P. harmala rhizosphere soil. We thus suspect that P. harmala might produce harmaline as an effective carry-on pesticide to defend against general pathogens such as Alternaria sp. and Fusarium sp. and favor itself. Our consecutive cultivation procedure has successfully magnified the core signals from the chaotic data, implying that it can be applied to measure the effects of other allelochemicals on soil microbiota.

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“…The main glycoalkaloids in potato, α-solanine, and α-chaconine showed a potent antimicrobial activity to a wide range of organisms; for this reason, they are considered as defensive allelochemicals [ 45 ]. On the basis of their fungal control potential, they are also formulated in silver nanoparticles as ecofriendly alternatives to conventional fungicides against different phytopathogens, including R. solani [ 46 ]. Among them, α-chaconine demonstrated higher antifungal activity compared to α-solanine [ 47 , 48 ].…”

Section: Discussionmentioning

confidence: 99%

Managing Rhizoctonia Damping-Off of Rocket (Eruca sativa) Seedlings by Drench Application of Bioactive Potato Leaf Phytochemical Extracts

Pane

Caputo

Francese

et al. 2020

Biology

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Plants produce a huge array of secondary metabolites that play a key role in defense mechanisms against detrimental microorganisms and herbivores, and represent a suitable alternative to synthetic fungicides in sustainable agriculture. In this work, twelve crude hydroethanolic extracts derived from leaves of different potato cultivars were chemically characterized by LC/MS and their antioxidant properties were investigated in vitro. Furthermore, the biological activity against the fungal pathogen Rhizoctonia solani was evaluated both in vitro and in vivo. Extracts showed the ability to inhibit R. solani growth in vitro and significantly reduced damping-off incidence in in vivo experiments. Furthermore, R. solani mycelia exposed to the extracts showed an altered morphology (low translucency, irregular silhouette, and cytoplasmatic content coagulation) compared to the untreated control in light microscopy examination. Principal component analysis conducted on identified chemical compounds highlighted significant metabolic variations across the different extracts. In particular, those that inhibited most of the growth of the pathogen were found to be enriched in α-chaconine or α-solanine content, indicating that their biological activity is affected by the abundance of these metabolites. These results clearly indicated that plant-derived compounds represent a suitable alternative to chemicals and could lead to the development of new formulates for sustainable control of plant diseases.

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Ecofriendly Synthesis of Silver Nanoparticles Using Potato Steroidal Alkaloids and Their Activity Against Phytopathogenic Fungi

Cited by 18 publications

References 44 publications

Cytotoxic, Antimitotic, DNA Binding, Photocatalytic, H2O2 Sensing, and Antioxidant Properties of Biofabricated Silver Nanoparticles Using Leaf Extract of Bryophyllum pinnatum (Lam.) Oken

Cytotoxic, Antimitotic, DNA Binding, Photocatalytic, H2O2 Sensing, and Antioxidant Properties of Biofabricated Silver Nanoparticles Using Leaf Extract of Bryophyllum pinnatum (Lam.) Oken

Changes in the Soil Fungal Community Mediated by a Peganum harmala Allelochemical

Managing Rhizoctonia Damping-Off of Rocket (Eruca sativa) Seedlings by Drench Application of Bioactive Potato Leaf Phytochemical Extracts

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