EXTRACTION OF BIOACTIVE COMPOUNDS OF LEAVES OF Duguetia furfuracea (ANNONACEAE) USING GREEN AND ORGANIC SOLVENTS

Abstract

Duguetia furfuracea (Annonaceae) is a shrub found in the Brazilian Cerrado that is used in popular medicine as an antirheumatic, for wound healing, treatment of kidney pain and against pediculosis. The aim of this study was to analyze the extraction of leaves of Duguetia furfuracea, using supercritical CO 2 , ethanol and hexane as solvents. For the supercritical extraction, an experimental planning 2 3 with triplicates of the central point was used to evaluate the effects of temperature (313-333 K), pressure (15-23 MPa) and volumetric flow rate (3-6 mL min -1 ) on the extraction yield, total phenolic content and antioxidant activity compared with extracts obtained by Soxhlet extraction. The effects of the variables on the extraction yield were positive and the pressure had greater influence. However, the highest performances, total phenolic content and antioxidant activities were obtained by the Soxhlet method. The mathematical model based on the Brunauer-Emmett-Teller theory of adsorption correlated satisfactorily the experimental values of the supercritical extraction.

Produtos naturais no controle de Colletotrichum sp. associado a pimenta-de-cheiro (Capsicum chinense Jacq.)

“…Pesquisas mostram que algumas plantas têm seus metabólitos antimicrobianos extraídos com solventes polares, como a água, resultando em efeitos inibitórios no desenvolvimento de microrganismos patogênicos, no entanto, outras apresentam atividade inibitória dependente do solvente apolares ou de média polaridade utilizados na obtenção dos extratos e da concentração testada, (Mohsan, Ali, Shahbaz, Saeed, & Burhan, 2017;Ezeonu et al, 2019). Métodos como destilação a vapor ou extração com solventes orgânicos são muito utilizados para extração de metabolitos ativos (Abidin, Hayyan, Hayyan, & Jayakumar, 2017;Favareto et al, 2019), e que mostram respostas promissoras inibindo o desenvolvimento de fitopatógenos.…”