Estimated prevalence of COVID-19 in Brazil with probabilistic bias correction

Figueirêdo, Erik Alencar de; Polli, Démerson André; Andrade, Bernardo Borba de

doi:10.1590/0102-311x00290120

Cited by 5 publications

(4 citation statements)

References 11 publications

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“…However, indirect comparisons with other studies may suggest a higher risk attributed to OHCWs. In Brazil, for instance, the prevalence of SARS-CoV-2 infection in the same period studied was estimated about 15% in the general population, 54 meanwhile the study by Ferreira et al 41 included in our systematic review indicated the prevalence of 22% for OHCWs. However, none of the studies included in this study examined at the potential source of infection among OHCWs, limiting the possibility of assessing the impact of occupational versus community-acquired infection.…”

Section: F I G U R E 5 Bubble Plot For Meta-regression Of Human Devel...mentioning

confidence: 75%

Prevalence of SARS‐CoV‐2 infection among oral health care workers worldwide: A meta‐analysis

Bitencourt

Lia

Pauletto

et al. 2022

Comm Dent Oral Epid

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ObjectivesThis systematic review aimed to answer the following question ‘What are the worldwide prevalence of SARS‐CoV‐2 infection and associated factors among oral health‐care workers (OHCWs) before vaccination?’MethodsSeven databases and registers as well as three grey databases were searched for observational studies in the field. Paired reviewers independently screened studies, extracted data and assessed the methodological quality. Overall seroprevalence for SARS‐CoV‐2 infection was analysed using a random‐effect model subgrouped by professional category. Meta‐regression was used to explore whether the Human Development Index (HDI) influenced the heterogeneity of results. The associated factors were narratively evaluated, and the certainty of the evidence was assessed using the GRADE approach.ResultsSeventeen studies were included (five cohorts and twelve cross‐sectional studies), summing 73 935 participants (54 585 dentists and 19 350 dental assistants/technicians) from 14 countries. The overall estimated pooled prevalence of SARS‐CoV‐2 infection among OHCWs was 9.3% (95% CI, 5.0%–14.7%; I2 = 100%, p < .01), being 9.5% for dentists (95% CI, 5.1%–15.0%; I2 = 100%, p < .01) and 11.6% for dental assistants/technicians (95% CI, 1.6%–27.4%; I2 = 99.0%, p < .01). In the meta‐regression, countries with lower HDI showed higher prevalence of SARS‐CoV‐2 infection (p = .002). Age, comorbidities, gender, ethnicity, occupation, smoking, living in areas of greater deprivation, job role and location/municipalities, income and protective measures in dental settings were associated with positive serological SARS‐CoV‐2 test, with very low certainty of evidence.ConclusionsThe SARS‐CoV‐2 virus infected 9.3% of the OHCWs evaluated worldwide before vaccination. OHCWs should be included in policy considerations, continued research, monitoring and surveillance (PROSPERO CRD42021246520).

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Section: F I G U R E 5 Bubble Plot For Meta-regression Of Human Devel...mentioning

confidence: 75%

Prevalence of SARS‐CoV‐2 infection among oral health care workers worldwide: A meta‐analysis

Bitencourt

Lia

Pauletto

et al. 2022

Comm Dent Oral Epid

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“…For example, the prevalence of anti-S IgG antibodies for SARS-CoV-2 in an extremely socioeconomic vulnerable population in Rio de Janeiro and Salvador before vaccine implementation was higher than previous estimates for these cities, indicating the significant burden of COVID-19 in these communities 10 11. The unavailability of diagnostic tools is aggravated by the arrival of new SARS-CoV-2 variants, also contributing to under-reporting of cases 8 9…”

Section: Introductionmentioning

confidence: 95%

“…In this context, testing and diagnosis are still insufficient,5 6 mainly in areas with more significant socioeconomic disadvantages, such as low-income and middle-income countries. Low-income countries’ investments in public health are often insufficient in these settings,7 leading to increase in the number of under-reported cases 8 9. For example, the prevalence of anti-S IgG antibodies for SARS-CoV-2 in an extremely socioeconomic vulnerable population in Rio de Janeiro and Salvador before vaccine implementation was higher than previous estimates for these cities, indicating the significant burden of COVID-19 in these communities 10 11.…”

Section: Introductionmentioning

confidence: 98%

Expansion of testing, isolation, quarantine, e-health and telemonitoring strategies in socioeconomically vulnerable neighbourhoods at primary healthcare in the fight against COVID-19 in Brazil: a study protocol of a multisite testing intervention using a mixed method approach

et al. 2023

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IntroductionThe key tools for mitigating the impact of COVID-19 and reducing its transmission include testing, quarantine and isolation, as well as telemonitoring. Primary healthcare (PHC) can be essential in increasing access to these tools. Therefore, the primary objective of this study is to implement and expand an intervention consisting of COVID-19 testing, isolation, quarantine and telemonitoring (TQT) strategies and other prevention measures at PHC services in highly socioeconomically vulnerable neighbourhoods of Brazil.Methods and analysisThis study will implement and expand COVID-19 testing in PHC services in two large Brazilian capital cities: Salvador and Rio de Janeiro. Qualitative formative research was conducted to understand the testing context in the communities and at PCH services. The TQT strategy was structured in three subcomponents: (1) training and technical support for tailoring the work processes of health professional teams, (2) recruitment and demand creation strategies and (3) TQT. To evaluate this intervention, we will conduct an epidemiological study with two stages: (1) a cross-sectional sociobehavioural survey among individuals from these two communities covered by PHC services, presenting symptoms associated with COVID-19 or being a close contact of a patient with COVID-19, and (2) a cohort of those who tested positive, collecting clinical data.Ethics and disseminationThe WHO Ethics Research Committee (ERC) (#CERC.0128A and #CERC.0128B) and each city’s local ERC approved the study protocol (Salvador, ISC/UFBA: #53844121.4.1001.5030; and Rio de Janeiro, INI/Fiocruz: #53844121.4.3001.5240, ENSP/Fiocruz: #53844121.4.3001.5240 and SMS/RJ #53844121.4.3002.5279). Findings will be published in scientific journals and presented at meetings. In addition, informative flyers and online campaigns will be developed to communicate study findings to participants, members of communities and key stakeholders.

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“…In Brazil, in 2020, the seroprevalence of antibodies against SARS-CoV-2 was considered low, ranging from 3 to 15%, totaling approximately 212 million people infected before the start of vaccination against Covid-19, which in this country, began on January 17, 2021 [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of vaccination against Covid-19 one year after its introduction in Brazil

Pércio

Cabral

Fantinato

et al. 2022

Trop Dis Travel Med Vaccines

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Background Worldwide, several efforts have been made to develop, distribute and administer safe and effective vaccines to reduce morbidity and mortality and control the Covid-19 pandemic. This study aimed to analyze the effect of vaccination against Covid-19, one year after its introduction in Brazil. Methods An ecological study that analyzed the general effect of vaccination against Covid-19 on disease morbidity and mortality indicators among the Brazilian population aged 18 years or older per epidemiological week (EW), comparing the pre and postvaccination period. Morbidity and mortality indicators were calculated from secondary databases (hospitalization rate, severity, case fatality rate and mortality) and vaccination coverage by age groups (18 to 59 years and 60 years or older). Morbimortality trends were estimated using the JoinPoint model and their association with vaccine coverage using the Poisson model. Results The average weekly percentage change (AWPC) of morbidity and mortality indicators reduced after the introduction of Covid-19 vaccination: hospitalization rate (from 15.3% to -6.0%), severity (from 0.4% to -0.2%), case fatality rate (from 0.3% to -0.2%) and mortality (from 20.5% to -4.3%). The following indicators were inversely associated with the increase in vaccine coverage against Covid-19: hospitalization (IRR: 0.974), mortality (IRR: 0.975) and lethality for people aged 60 years or older (IRR: 0.997). Conclusions In spite of the three epidemic waves and the circulation of variants of concern, the general effect of vaccination against Covid-19 in reducing the trend of morbidity and mortality from the disease in Brazil was demonstrated. These findings contribute to a better understanding of the mass vaccination program against Covid-19 and may inform future public health policies.

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Estimated prevalence of COVID-19 in Brazil with probabilistic bias correction

Cited by 5 publications

References 11 publications

Prevalence of SARS‐CoV‐2 infection among oral health care workers worldwide: A meta‐analysis

Prevalence of SARS‐CoV‐2 infection among oral health care workers worldwide: A meta‐analysis

Expansion of testing, isolation, quarantine, e-health and telemonitoring strategies in socioeconomically vulnerable neighbourhoods at primary healthcare in the fight against COVID-19 in Brazil: a study protocol of a multisite testing intervention using a mixed method approach

Effect of vaccination against Covid-19 one year after its introduction in Brazil

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