Plasmacytoma of the trachea: a surprising diagnosis

Duarte, Márcio Luí­s; Brito, Mariana Carneiro Barbosa de; Traple, Fabricius André Lyrio; Prado, José Luiz Masson de Almeida; Scoppetta, Luiz Carlos Donoso

doi:10.1590/0100-3984.2015.0112

Cited by 2 publications

(1 citation statement)

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“…The most frequent clinical symptoms in UAD are airway obstruction, epistaxis, rhinorrhea, pain, and swelling of the soft tissue 5,8. When EMP occurs in the trachea, dyspnea is the most common symptom and becomes more severe when the tracheal lumen is narrowed by >75% 9,10. In our case, airway obstruction was the only clinical manifestation before diagnosis, although the laryngopharynx and oropharynx showed swelling of the mucosa, which was found accidentally in the subsequent examination.…”

Section: Discussionmentioning

confidence: 99%

<p>Multiple extramedullary plasmacytomas of the trachea and pharyngeal tissue: a case report and literature review</p>

Tang¹,

Wang²,

Liang³

et al. 2019

OTT

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Extramedullary plasmacytoma (EMP) is an infrequent form of plasma cell dyscrasia that presents as a mass of monoclonal plasma cells located in extramedullary soft tissues with no skeletal component. EMP constitutes ~4% of all plasma cell neoplasms and occurs mostly in the upper respiratory tract. Here, we report a rare case of multiple EMPs involving the trachea, laryngopharynx, and oropharynx, which caused symptoms of airway obstruction as the only clinical manifestation. The patient was diagnosed by histopathology of the tissue from bronchoscopic resection and successfully managed with bronchoscopic intervention to treat lesions in the trachea and radiotherapy combined with surgical resection to treat lesions in the pharynx. There was no recurrence after 14 months of follow-up. Endoscopic intervention plays a key role in the rapid diagnosis and treatment of EMP involving the central airways.

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Section: Discussionmentioning

confidence: 99%