Due to the complexity of human psychology, well-being depends on many factors, so it is helpful to consider different aspects in a multidisciplinary way. However, it is still unclear how these factors, which are the keys to a better life, will be affected by digital transformation. There are both challenges and opportunities in areas such as work-life balance, social connections, civic engagement, and governance. From this point of view, in this chapter, firstly the digitalization process, then the concepts of psychological adjustment and digital well-being, are mentioned.