Effect of FPZ, a total flavonoids ointment topical application from Pouzolzia zeylanica var. microphylla, on mice skin infections

Chen, Xian-Mei; Li, Zhihui; Tao, Shu-Hong; Chen, Yanfen; Chen, Zhuo-Han; Guo, Libing

doi:10.1016/j.bjp.2018.08.009

Cited by 3 publications

(4 citation statements)

References 13 publications

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“…More than sixty plants used for green AgNP synthesis were summarized [11,14], but Phyllanthus urinaria (P. urinaria), Pouzolzia zeylanica (P. zeylanica), and Scoparia dulcis (S. dulcis) are plants of interest that have not yet been explored. P. urinaria, P. zeylanica, and S. dulcis are traditional herbs distributed mainly in tropical countries [22][23][24][25][26][27]. In folk medicine, P. urinaria is well known as a remedy for treating many diseases, including diabetes, jaundice, malaria, cancer, infection, and liver diseases [24][25][26].…”

Section: Introductionmentioning

confidence: 99%

“…In folk medicine, P. urinaria is well known as a remedy for treating many diseases, including diabetes, jaundice, malaria, cancer, infection, and liver diseases [24][25][26]. P. zeylanica shows its effects in anti-bacteria, anti-inflammation, anti-allergic, antioxidant, anti-snake venom activities, antiasthma, and pain relief [22,23,28]. S. dulcis is also known for its medicinal functions in treatment of inflammation, hemorrhoids, bronchitis, urinary disorders, diabetes, hypertension, kidney stones, stomach ailments, hepatosis, insect bites, fever, diarrhea, cancer, and ulcers [29,30].…”

Section: Introductionmentioning

confidence: 99%

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Green Silver Nanoparticles Formed by Phyllanthus urinaria, Pouzolzia zeylanica, and Scoparia dulcis Leaf Extracts and the Antifungal Activity

et al. 2020

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Phytoconstituents presenting in herbal plant broths are the biocompatible, regenerative, and cost-effective sources that can be utilized for green synthesis of silver nanoparticles. Different plant extracts can form nanoparticles with specific sizes, shapes, and properties. In the study, we prepared silver nanoparticles (P.uri.AgNPs, P.zey.AgNPs, and S.dul.AgNPs) based on three kinds of leaf extracts (Phyllanthus urinaria, Pouzolzia zeylanica, and Scoparia dulcis, respectively) and demonstrated the antifungal capacity. The silver nanoparticles were simply formed by adding silver nitrate to leaf extracts without using any reducing agents or stabilizers. Formation and physicochemical properties of these silver nanoparticles were characterized by UV-vis, Fourier transforms infrared spectroscopy, scanning electron microscope, transmission electron microscope, and energy dispersive X-ray spectroscopy. P.uri.AgNPs were 28.3 nm and spherical. P.zey.AgNPs were 26.7 nm with hexagon or triangle morphologies. Spherical S.dul.AgNPs were formed and they were relatively smaller than others. P.uri.AgNPs, P.zey.AgNPs and S.dul.AgNPs exhibited the antifungal ability effective against Aspergillus niger, Aspergillus flavus, and Fusarium oxysporum, demonstrating their potentials as fungicides in the biomedical and agricultural applications.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Green Silver Nanoparticles Formed by Phyllanthus urinaria, Pouzolzia zeylanica, and Scoparia dulcis Leaf Extracts and the Antifungal Activity

et al. 2020

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“…Different plants for the formation of silver nanoparticles were previously investigated (Pulit-Prociak and Banach, 2016). Phyllanthus urinaria, Pouzolzia zeylanica, and Scoparia dulcis are herbs of great importance in the world, and have anti-bacteria, anti-inflammatory, anti-allergic, antioxidant, and many other potential activities (Hossain et al, 2017;Chen et al, 2018;Frezza et al, 2020). Under moderate conditions, three kinds of silver nanoparticles were actively biosynthesized (P.uri.AgNPs, P.zey.AgNPs, and S.dul.AgNPs), simply by applying silver (I) to these herbal plant minerals.…”

Section: Silver Nanoparticles Against Fungal Pathogensmentioning

confidence: 99%

Fabrication of Silver Nanoparticles Against Fungal Pathogens

Mansoor

Zahoor

Baba

et al. 2021

Front. Nanotechnol.

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The use of silver nanoparticles (AgNPs) against various pathogens is now being well recognized in the agriculture and health sector. Nanoparticles have been shown to exhibit various novel properties and these properties, on other hand, rely upon the size, shape, and morphology of these particles. Moreover, these physical characteristics enable them to interact with microbes, plants, and animals. Smaller-sized particles have shown more toxicity than larger-sized nanoparticles. AgNPs have shown growth inhibition of many fungi like Aspergillus fumigates, A. niger, A. flavus, Trichophyton rubrum, Candida albicans, and Penicillium species. According to the current hypothesis, AgNPs act by producing reactive oxygen species and free radicals, which cause protein denaturation, nucleic acid and proton pump damage, lipid peroxidation, and cell wall damage. Therefore, they alter the cell membrane permeability, causing cell death. This mini-review summarizes the use of silver nanoparticles against fungal pathogens and fungal biofilm in the agricultural sector.

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“…The water content of albumin ointment which has the highest value is 0.4% collagen concentration of 2.40%, and the lowest result is 0.8% concentration of 2.24%. The water content of the albumin ointment produced was lower than the water content of the ointment in the study of Chen, et al, (2018), which was 19.1%. According to Pratama, et al, (2014), the water content is influenced by the water content of the added material.…”

Section: Figure 5 the Results Of Water Contentmentioning

confidence: 57%

Effect of Addition of Tiger Grouper (Epinephelus fuscoguttatus) Skin Collagen to Cork Fish (Channa striata) Albumin Ointment on Closure of Cuts

Gunawan¹,

Suprayitno²

2021

IJSRP

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Ointments are semisolid preparations intended for topical application to the skin or mucous membranes. The ointment formulation requires the presence of an ointment base, the ointment base itself is an inactive carrier substance from topical preparations that can be in the form of liquid or solid which brings the active ingredient to contact with the skin. The ointment base used in an ointment formulation must be inert in other words not to damage or reduce the therapeutic effect of the drug it contains. The results of the first study showed that differences in collagen concentrations affected the quality of albumin ointment, namely pH, viscosity, protein content, fat content, and water content. The best albumin ointment was obtained at 0.8% collagen concentration with the following results pH 6.8, viscosity 27980 cP, protein content 1.34%, fat content 88.29%, and water content 2.24%. The results of the amino acid profile test showed that the highest result was Glycine 5618.18 mg/kg and the lowest was L-Tyrosine <66.93 mg/kg. Then continued in the second study, namely amino acid profile testing, zinc levels and experimental mice, the results of observations on day 3, day 5, and day 7 showed that the best concentration of albumin ointment treatment underwent a wound closure process. 75% on the 7th day.

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Effect of FPZ, a total flavonoids ointment topical application from Pouzolzia zeylanica var. microphylla, on mice skin infections

Cited by 3 publications

References 13 publications

Green Silver Nanoparticles Formed by Phyllanthus urinaria, Pouzolzia zeylanica, and Scoparia dulcis Leaf Extracts and the Antifungal Activity

Green Silver Nanoparticles Formed by Phyllanthus urinaria, Pouzolzia zeylanica, and Scoparia dulcis Leaf Extracts and the Antifungal Activity

Fabrication of Silver Nanoparticles Against Fungal Pathogens

Effect of Addition of Tiger Grouper (Epinephelus fuscoguttatus) Skin Collagen to Cork Fish (Channa striata) Albumin Ointment on Closure of Cuts

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