Multinucleate cell angiohistiocytoma: an uncommon cutaneous tumor

Costa, Anderson Alves; Wedy, Glaucia Ferreira; Belda, Walter; Criado, Paulo Ricardo

doi:10.1016/j.abd.2019.10.005

Cited by 3 publications

(6 citation statements)

References 10 publications

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“…There is usually a unilateral presentation, but bilateral and generalized forms have been reported. 2 Proliferation of vessels, fibroblasts, and angulated multinucleated cells are characteristic for MCAH. Roy and colleagues proposed 4 histologic criteria (Table 1) for diagnosing MCAH.…”

Section: Discussionmentioning

confidence: 99%

Multinucleate Cell Angiohistiocytoma Treated With a 650 Microsecond Nd:YAG 1064 Laser

Le¹,

Jacobson²,

Ros

2021

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through at any given time. 1 These microchannels additionally limit the depth to which the PLLA can penetrate, which likely affects the immune system's response and subsequent granulomatous processes. In contrast to typical injections using focal volumes of PLLA, LADD distributes very small volumes of PLLA throughout the treatment area. There are major differences in the amount of PLLA that is ultimately placed in the dermis.Although limited by its retrospective and single-center design, our study demonstrates the safety of fractional ablative laser-assisted delivery of topical PLLA. However, additional prospective, controlled studies would be beneficial to further confirm these results. Physicians who may be apprehensive of applying topical PLLA after ablative laser treatment should be reassured by these data.

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Section: Discussionmentioning

confidence: 99%

Multinucleate Cell Angiohistiocytoma Treated With a 650 Microsecond Nd:YAG 1064 Laser

Le¹,

Jacobson²,

Ros

2021

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“…4 The papules are mainly located on acral sites, usually unilateral, 4 but the face is also a common location. 5…”

Section: Introductionmentioning

confidence: 99%

“…4 The papules are mainly located on acral sites, usually unilateral, 4 but the face is also a common location. 5 The pathogenesis of this condition is complex, probably involving chronic inflammatory stimuli to which MCAH could be a reactive process. 3 Expression of estrogen receptor (ER) by the stromal ells in some cases of these lesions may partly explain its female preponderance.…”

Section: Introductionmentioning

confidence: 99%

Pigmented Multinucleate Cell Angiohistiocytoma: First Case

Fernández-Flores

2022

The American Journal of Dermatopathology

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Multinucleate cell angiohistiocytoma (MCAH) is a benign vascular and fibrohistiocytic (probably reactive) proliferation with peculiar multinucleate cells which most authors interpret as degenerated macrophages. Several clinical variants of MCAH have been described, some of them with brownish-appearing lesions clinically. However, no histologically identified pigment has been described in the cytoplasm of the multinucleate cells so far. We present a pigmented MCAH with cytoplasmic brownish pigment, which was positive with a Masson-Fontana stain and negative with an iron stain, consistent with melanin, in a 33-year-old woman with multiple papules and plaques on the right elbow, right jawline, and left flank.

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“…1 Aunque la patogenia de esta enfermedad es desconocida, la hipótesis que predomina sugiere que cowww.medigraphic.com/dermatologicopascua www.medigraphic.org.mx rresponde a un proceso reactivo más que neoplásico. 3 Lo anterior, tomando en cuenta que es una dermatosis benigna con comportamiento indolente, ausencia de involucro extracutáneo, sin transformación maligna y posibilidad de involución espontánea. 3 Desde el punto de vista clínico se distinguen dos variedades.…”

Section: Introductionunclassified

“…3 Lo anterior, tomando en cuenta que es una dermatosis benigna con comportamiento indolente, ausencia de involucro extracutáneo, sin transformación maligna y posibilidad de involución espontánea. 3 Desde el punto de vista clínico se distinguen dos variedades. La forma clásica o localizada es la que predomina, de evolución lenta (de meses a años) pero progresiva, más frecuente en mujeres (79%), 4 edad media 50 años, 5 común en las extremidades (manos, 30%) y cabeza (cara, 29%).…”

Section: Introductionunclassified

Angiohistiocitoma de células multinucleadas

Navarrete-Franco¹,

González-González²,

Ramos-Garibay³

et al. 2022

Revista Del Centro Dermatológico Pascua

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El angiohistiocitoma de células multinucleadas (AHCMN) es una proliferación vascular y fibrohistiocítica de origen aún incierto. Descrito por primera vez por Smith y Wilson-Jones en 1985, es una dermatosis poco frecuente; la forma clásica afecta sobre todo a mujeres de edad media y suele presentarse de forma unilateral, afectando con frecuencia regiones acrales y cara. Morfológicamente son neoformaciones numerosas, cupuliformes, de superficie lisa, eritematosas, eritematovioláceas y/o marrón, aisladas y/o confluentes, formando placas de forma y tamaño variable. Se han descrito casos diseminados con características epidemiológicas y morfológicas diferentes. El diagnóstico se basa en los hallazgos histopatológicos, que incluyen proliferación vascular capilar en la dermis superficial con presencia de células multinucleadas inmersas en un estroma fibroso. El cuadro evoluciona en forma lenta y tiende a ser persistente; aunque existen casos de involución espontánea. El tratamiento de elección es la extirpación quirúrgica, cuando es posible, y la vigilancia es una alternativa ante la naturaleza benigna de esta entidad.Palabras clave: angiohistiocitoma de células multinucleadas.

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Multinucleate cell angiohistiocytoma: an uncommon cutaneous tumor

Cited by 3 publications

References 10 publications

Multinucleate Cell Angiohistiocytoma Treated With a 650 Microsecond Nd:YAG 1064 Laser

Multinucleate Cell Angiohistiocytoma Treated With a 650 Microsecond Nd:YAG 1064 Laser

Pigmented Multinucleate Cell Angiohistiocytoma: First Case

Angiohistiocitoma de células multinucleadas

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