1-Benzoyl-2-thiobiuret: rearrangement and cyclization

Pro-apoptotic and pro-differentiation induction by 8-quinolinecarboxaldehyde selenosemicarbazone and its Co(iii) complex in human cancer cell lines

“…Selenosemicarbazones are Schiff bases obtained by the condensation reaction of carbonyl compounds and selenosemicarbazides. They showed antiparasitic, 1 antifungal, 2,3 antibacterial, [3][4][5][6] antimalarial, [7][8][9][10] anticancer, 3,7,10-23 antioxidant 3,14 and antidiabetic 14 activity. In order to obtain more active species, complexes of PtIJII), PdIJII), ZnIJII), CdIJII), AuIJI), NiIJII), CoIJIII), GaIJIII), SnIJIV) and CuIJII) have been prepared and tested against malaria 10,24,25 and microorganisms [3][4][5] as well as cancer cell lines.…”

Synthesis, Spectral, Antimicrobial and In vitro Antitumorous Studies of Copper based mulltidentate thiosemicarbazones

“…The already reported procedure was used to prepare compounds 4-methyl-4-phenyl-3-thiosemicarbazide and carboxymethyl-Nmethyl-N-phenyl dithiocarbamate. 15,16 Equimolar amounts of 4-methyl-4-phenyl-3-thiosemicarbazide (1 g, 5.52 mmol) dissolved in 5 mL hot methanol along with 2-benzoylpyridine (1.011 g, 5.52 mmol) and N-phenyl piperazine (0.84 mL, 5.52 mmol) separately dissolved in 10 mL methanol (99.9%) were refluxed for 45 min at 50°C. The resulting solution was left to chill which yielded 40% (0.160 g)yellow shining microcrystals of HL 2 .…”