1,2,3-Triazoles based 3-substituted 2-thioquinoxalines: Synthesis, anti-bacterial activities, and molecular docking studies

Nano nickel [1,2,4]‐triazole‐3‐thiones complex: Design, sonochemical synthesis, and antimicrobial evaluation

“…[13,14] 1,2,4-Triazoles chemistry are fascinating heterocycles and their derivatives specially they belong to isothiocyanates (ITCs) [15][16][17][18][19][20][21] class. Also, they possess significant pharmacological activities such as antitumor, [22] antifungal, [23] antiviral, [24] stimulants sedatives, [25][26] anti-inflammatory, [27] and antimycotic agents, [28] for example, 1 fluconazole, 2 voriconazole, 3 Fluconazole, 4 itraconazole, 5 Triazolam, 6 Alprazolam, and 7 Etizolam (Figure 1).…”

A Facile Environ-friendly One-pot Water-promoted Synthesis of Bis 1,2,3-triazole Linked Bis 2 - Aminopyrimidine Hybrids

“…Nitrogen-containing organic compounds play very vital roles in the research areas of organic chemistry, medicinal chemistry, and pesticidal chemistry. In recent times, the chemistry of heterocyclic triazole derivatives and 2-amino pyrimidine derivatives has attracted much attention owing to their versatile pharmacological properties 1,2,3 .…”

New Derivatives of 5-((1-Methyl-Pyrrol-2-yl) Methyl)-4-(Naphthalen-1-yl)-1,2,4-Triazoline-3-Thione and Its Coordination Compounds with Anticancer Activity

“…Important pharmacologicals of heterocyclic compounds include 1,2,4-triazoles and their derivatives, which have received much attention because of their interesting biological activities [ 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 ]. 1,2,4-Triazoles are present as a unit in a variety of drugs marketed as antineoplastic [ 44 ], antifungal [ 45 ], antiviral [ 46 ], sedative stimulants [ 46 , 47 , 48 ], anti-inflammatory [ 49 ] and antimycotics agents [ 50 ] Triazole-based drugs are shown in Figure 1 . The conception and tuning of ligand capabilities can ultimately lead to an innovative area of metal chemistry [ 51 , 52 , 53 ].…”