A 24-day-old boy was admitted to our hospital with fever. Three days after admission, his condition worsened, and he presented with reticular cyanosis. He was diagnosed with sepsis-like syndrome. Human parechovirus type 4 was detected in serum and stool samples by reverse transcription polymerase chain reaction and sequencing. His condition improved after intravenous gamma-globulin treatment. There are few reports of sepsis-like syndrome caused by human parechovirus type 4, and its clinical features and treatment have not been established, but immunoglobulin therapy may be effective in severe cases.
Patient was a 6-year-old boy, who was admitted to our hospital with fever persisting for more than 2 weeks. After admission, he had no clinical symptoms other than the fever. On the 24th day after the onset of fever, the patient developed bladder and bowel dysfunction and gait disturbance. Cerebrospinal fluid analysis showed pleocytosis, and the IgG index was elevated. From his clinical and laboratory findings, he was diagnosed with transverse myelitis. Two courses of methyl-prednisolone pulse therapy were administered. After treatment, his symptoms improved without neurological sequelae. Autoimmune neuropathy usually progresses rapidly, but our case shows that it can sometimes progress subacutely. Transverse myelitis should be considered as one of the causes for prolonged fever.
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