Effects of Euglena dry cells on the absorption and metabolism of cholesterol were studied with rats by comparing the Euglena-diet, in which 75% of total protein was replaced with Euglena dry cells, with a casein diet. No significant difference was found between the Euglena-diet and the casein-diet groups in body weight and relative weight of organs. Excretion of [14C]-labeled-cholesterol to feces was more in the Euglena-diet group than in the casein-diet group and retention time of cholesterol in digestive tract was shorter in the Euglena-diet group than in the casein-diet group, resulting in low tissue-distribution of cholesterol radioactivity in the Euglena-diet group. No significant difference was found between these two groups in tissue-distribution ratio of absorbed labeled-cholesterol radioactivity.
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